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• W2117316805 abstract "In order to achieve a better understanding of multiple infections and long latency in the dynamics of Mycobacterium tuberculosis infection, we analyze a simple model. Since backward bifurcation is well documented in the literature with respect to the model we are considering, our aim is to illustrate this behavior in terms of the range of variations of the model's parameters. We show that backward bifurcation disappears (and forward bifurcation occurs) if: (a) the latent period is shortened below a critical value; and (b) the rates of super-infection and re-infection are decreased. This result shows that among immunosuppressed individuals, super-infection and/or changes in the latent period could act to facilitate the onset of tuberculosis. When we decrease the incubation period below the critical value, we obtain the curve of the incidence of tuberculosis following forward bifurcation; however, this curve envelops that obtained from the backward bifurcation diagram." @default.
• W2117316805 created "2016-06-24" @default.
• W2117316805 creator A5018106439 @default.
• W2117316805 creator A5071684157 @default.
• W2117316805 date "2010-11-08" @default.
• W2117316805 modified "2023-10-17" @default.
• W2117316805 title "Assessing the effects of multiple infections and long latency in the dynamics of tuberculosis" @default.
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• W2117316805 doi "https://doi.org/10.1186/1742-4682-7-41" @default.
• W2117316805 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2995482" @default.
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