FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117323415> ?p ?o ?g. }

• W2117323415 endingPage "639" @default.
• W2117323415 startingPage "633" @default.
• W2117323415 abstract "ABSTRACT The surface-associated glycopeptides gp40, one of the most polymorphic Cryptosporidium antigens, and gp15, one of the most immunodominant Cryptosporidium antigens, are putative vaccine candidates because they mediate infection in vitro and induce immune responses in vivo . We evaluated antibody responses to these antigens before and after the first episode of symptomatic cryptosporidiosis in 51 children from a birth cohort study in an area in South India where Cryptosporidium is endemic and a major cause of parasitic diarrhea. IgG levels to gp15 and to homotypic and heterotypic gp40 antigens were measured in pre- and postdiarrheal sera by enzyme-linked immunosorbent assay (ELISA). There was a significant IgG response to gp15 ( P < 0.001) following the first episode of cryptosporidial diarrhea. Using a general additive model, we determined the estimated time of the peak IgG response to gp15 to be 9.3 weeks (confidence interval, 5.2 to 13.4) following the diarrheal episode. In a subset of 30 children infected with Cryptosporidium hominis subtype Ia, there was a significant difference in IgG responses to homotypic C. hominis Ia and to heterotypic Cryptosporidium parvum II gp40 antigens ( P = 0.035). However, there was also a significant correlation ( P = 0.001) in the responses to both antigens in individual children, suggesting that while responses are in part subtype specific, there is significant cross-reactivity to both antigens. This is the first report of the characterization of immune responses to cryptosporidiosis in Indian children and the first study to investigate human immune responses to the polymorphic gp40 antigen. However, further studies are needed to determine whether immune responses to these antigens are protective against subsequent infections." @default.
• W2117323415 created "2016-06-24" @default.
• W2117323415 creator A5013890881 @default.
• W2117323415 creator A5038574950 @default.
• W2117323415 creator A5041578848 @default.
• W2117323415 creator A5061371711 @default.
• W2117323415 creator A5063260881 @default.
• W2117323415 creator A5063588260 @default.
• W2117323415 creator A5073174184 @default.
• W2117323415 creator A5078621129 @default.
• W2117323415 creator A5079371724 @default.
• W2117323415 date "2011-02-02" @default.
• W2117323415 modified "2023-10-14" @default.
• W2117323415 title "Serum IgG Response to Cryptosporidium Immunodominant Antigen gp15 and Polymorphic Antigen gp40 in Children with Cryptosporidiosis in South India" @default.
• W2117323415 cites W1983455118 @default.
• W2117323415 cites W1985976201 @default.
• W2117323415 cites W1990946936 @default.
• W2117323415 cites W1993192822 @default.
• W2117323415 cites W1996360869 @default.
• W2117323415 cites W1997464175 @default.
• W2117323415 cites W1999597481 @default.
• W2117323415 cites W2004593749 @default.
• W2117323415 cites W2005595540 @default.
• W2117323415 cites W2011932515 @default.
• W2117323415 cites W2017787837 @default.
• W2117323415 cites W2030611594 @default.
• W2117323415 cites W2038996517 @default.
• W2117323415 cites W2066452586 @default.
• W2117323415 cites W2068828166 @default.
• W2117323415 cites W2069647214 @default.
• W2117323415 cites W2090258240 @default.
• W2117323415 cites W2092917217 @default.
• W2117323415 cites W2092962144 @default.
• W2117323415 cites W2093960377 @default.
• W2117323415 cites W2096031010 @default.
• W2117323415 cites W2102833327 @default.
• W2117323415 cites W2103855849 @default.
• W2117323415 cites W2105145412 @default.
• W2117323415 cites W2106229951 @default.
• W2117323415 cites W2110947778 @default.
• W2117323415 cites W2113443519 @default.
• W2117323415 cites W2124500212 @default.
• W2117323415 cites W2125749896 @default.
• W2117323415 cites W2125883778 @default.
• W2117323415 cites W2128907164 @default.
• W2117323415 cites W2130258672 @default.
• W2117323415 cites W2135298445 @default.
• W2117323415 cites W2137143868 @default.
• W2117323415 cites W2142878401 @default.
• W2117323415 cites W2145092370 @default.
• W2117323415 cites W2146712078 @default.
• W2117323415 cites W2149682137 @default.
• W2117323415 cites W2154321650 @default.
• W2117323415 cites W2154456880 @default.
• W2117323415 cites W2154812117 @default.
• W2117323415 cites W2154888748 @default.
• W2117323415 cites W2164931560 @default.
• W2117323415 cites W2171054939 @default.
• W2117323415 cites W2171400837 @default.
• W2117323415 cites W2324308863 @default.
• W2117323415 cites W4298870098 @default.
• W2117323415 doi "https://doi.org/10.1128/cvi.00464-10" @default.
• W2117323415 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3122581" @default.
• W2117323415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21288997" @default.
• W2117323415 hasPublicationYear "2011" @default.
• W2117323415 type Work @default.
• W2117323415 sameAs 2117323415 @default.
• W2117323415 citedByCount "25" @default.
• W2117323415 countsByYear W21173234152012 @default.
• W2117323415 countsByYear W21173234152013 @default.
• W2117323415 countsByYear W21173234152014 @default.
• W2117323415 countsByYear W21173234152015 @default.
• W2117323415 countsByYear W21173234152016 @default.
• W2117323415 countsByYear W21173234152017 @default.
• W2117323415 countsByYear W21173234152018 @default.
• W2117323415 countsByYear W21173234152020 @default.
• W2117323415 countsByYear W21173234152021 @default.
• W2117323415 countsByYear W21173234152022 @default.
• W2117323415 countsByYear W21173234152023 @default.
• W2117323415 crossrefType "journal-article" @default.
• W2117323415 hasAuthorship W2117323415A5013890881 @default.
• W2117323415 hasAuthorship W2117323415A5038574950 @default.
• W2117323415 hasAuthorship W2117323415A5041578848 @default.
• W2117323415 hasAuthorship W2117323415A5061371711 @default.
• W2117323415 hasAuthorship W2117323415A5063260881 @default.
• W2117323415 hasAuthorship W2117323415A5063588260 @default.
• W2117323415 hasAuthorship W2117323415A5073174184 @default.
• W2117323415 hasAuthorship W2117323415A5078621129 @default.
• W2117323415 hasAuthorship W2117323415A5079371724 @default.
• W2117323415 hasBestOaLocation W21173234151 @default.
• W2117323415 hasConcept C126322002 @default.
• W2117323415 hasConcept C147483822 @default.
• W2117323415 hasConcept C159047783 @default.
• W2117323415 hasConcept C159654299 @default.
• W2117323415 hasConcept C203014093 @default.
• W2117323415 hasConcept C2777795018 @default.
• W2117323415 hasConcept C2778877831 @default.
• W2117323415 hasConcept C2779802037 @default.

• next