Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117367996> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2117367996 endingPage "2876" @default.
- W2117367996 startingPage "2863" @default.
- W2117367996 abstract "This study investigates (1) the effect of modifying the design of a dry powder inhaler on the device performance, and (2) which design features significantly contribute to overall inhaler performance. Computational Fluid Dynamics (CFD) analysis was performed to determine how the flowfield generated in an Aerolizer at 60 l min(-1) varied when the inhaler grid and mouthpiece were modified. The computational models were validated by Laser Doppler Velocimetry (LDV). Dispersion performance of the modified inhalers was measured with a mannitol powder using a multistage liquid impinger at 60 l min(-1). The inhaler grid was found to significantly affect the performance of the Aerolizer. As the grid voidage was increased, the amount of powder retained in the device doubled (due to increased tangential flow of particles in the inhaler mouthpiece) and the FPF(Loaded) was reduced from 57 to 44% (due to increased mouthpiece retention). The length of the mouthpiece played a lesser role on the inhaler performance, having no significant effect on the flowfield generated in the devices. In summary, the performance of a dry powder inhaler can be affected by simple design changes. CFD, coupled with experimental results, provides a rational basis for understanding the performance difference." @default.
- W2117367996 created "2016-06-24" @default.
- W2117367996 creator A5006213939 @default.
- W2117367996 creator A5022147961 @default.
- W2117367996 creator A5026411984 @default.
- W2117367996 creator A5026820693 @default.
- W2117367996 date "2004-11-01" @default.
- W2117367996 modified "2023-10-14" @default.
- W2117367996 title "Effect of Design on the Performance of a Dry Powder Inhaler Using Computational Fluid Dynamics. Part 1: Grid Structure and Mouthpiece Length" @default.
- W2117367996 cites W1503822147 @default.
- W2117367996 cites W1969619918 @default.
- W2117367996 cites W1974097079 @default.
- W2117367996 cites W1980803266 @default.
- W2117367996 cites W2003457369 @default.
- W2117367996 cites W2041601011 @default.
- W2117367996 cites W2042235503 @default.
- W2117367996 cites W2046036641 @default.
- W2117367996 cites W2046800088 @default.
- W2117367996 cites W2091415901 @default.
- W2117367996 cites W2107798013 @default.
- W2117367996 cites W271468622 @default.
- W2117367996 doi "https://doi.org/10.1002/jps.20201" @default.
- W2117367996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15389665" @default.
- W2117367996 hasPublicationYear "2004" @default.
- W2117367996 type Work @default.
- W2117367996 sameAs 2117367996 @default.
- W2117367996 citedByCount "166" @default.
- W2117367996 countsByYear W21173679962012 @default.
- W2117367996 countsByYear W21173679962013 @default.
- W2117367996 countsByYear W21173679962014 @default.
- W2117367996 countsByYear W21173679962015 @default.
- W2117367996 countsByYear W21173679962016 @default.
- W2117367996 countsByYear W21173679962017 @default.
- W2117367996 countsByYear W21173679962018 @default.
- W2117367996 countsByYear W21173679962019 @default.
- W2117367996 countsByYear W21173679962020 @default.
- W2117367996 countsByYear W21173679962021 @default.
- W2117367996 countsByYear W21173679962022 @default.
- W2117367996 countsByYear W21173679962023 @default.
- W2117367996 crossrefType "journal-article" @default.
- W2117367996 hasAuthorship W2117367996A5006213939 @default.
- W2117367996 hasAuthorship W2117367996A5022147961 @default.
- W2117367996 hasAuthorship W2117367996A5026411984 @default.
- W2117367996 hasAuthorship W2117367996A5026820693 @default.
- W2117367996 hasConcept C121332964 @default.
- W2117367996 hasConcept C126322002 @default.
- W2117367996 hasConcept C136229726 @default.
- W2117367996 hasConcept C1633027 @default.
- W2117367996 hasConcept C192562407 @default.
- W2117367996 hasConcept C199343813 @default.
- W2117367996 hasConcept C2776042228 @default.
- W2117367996 hasConcept C2777419714 @default.
- W2117367996 hasConcept C2780261241 @default.
- W2117367996 hasConcept C2780955776 @default.
- W2117367996 hasConcept C57879066 @default.
- W2117367996 hasConcept C71924100 @default.
- W2117367996 hasConceptScore W2117367996C121332964 @default.
- W2117367996 hasConceptScore W2117367996C126322002 @default.
- W2117367996 hasConceptScore W2117367996C136229726 @default.
- W2117367996 hasConceptScore W2117367996C1633027 @default.
- W2117367996 hasConceptScore W2117367996C192562407 @default.
- W2117367996 hasConceptScore W2117367996C199343813 @default.
- W2117367996 hasConceptScore W2117367996C2776042228 @default.
- W2117367996 hasConceptScore W2117367996C2777419714 @default.
- W2117367996 hasConceptScore W2117367996C2780261241 @default.
- W2117367996 hasConceptScore W2117367996C2780955776 @default.
- W2117367996 hasConceptScore W2117367996C57879066 @default.
- W2117367996 hasConceptScore W2117367996C71924100 @default.
- W2117367996 hasIssue "11" @default.
- W2117367996 hasLocation W21173679961 @default.
- W2117367996 hasLocation W21173679962 @default.
- W2117367996 hasOpenAccess W2117367996 @default.
- W2117367996 hasPrimaryLocation W21173679961 @default.
- W2117367996 hasRelatedWork W1552942501 @default.
- W2117367996 hasRelatedWork W1950566777 @default.
- W2117367996 hasRelatedWork W2050491411 @default.
- W2117367996 hasRelatedWork W2056840755 @default.
- W2117367996 hasRelatedWork W2058632936 @default.
- W2117367996 hasRelatedWork W2117367996 @default.
- W2117367996 hasRelatedWork W2138582447 @default.
- W2117367996 hasRelatedWork W2416171562 @default.
- W2117367996 hasRelatedWork W4281656742 @default.
- W2117367996 hasRelatedWork W2185565026 @default.
- W2117367996 hasVolume "93" @default.
- W2117367996 isParatext "false" @default.
- W2117367996 isRetracted "false" @default.
- W2117367996 magId "2117367996" @default.
- W2117367996 workType "article" @default.