Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117429194> ?p ?o ?g. }
- W2117429194 endingPage "e12337" @default.
- W2117429194 startingPage "e12337" @default.
- W2117429194 abstract "A major maternal adaptation in pregnancy is the large increase in uteroplacental blood flow that supplies the growing fetus with oxygen and nutrients. The impact of gestation on the dynamic uterine vasoconstrictor response to exercise in the rat, a common model for pathophysiological disorders in pregnancy remains unknown. We hypothesized that rats exhibit a robust uterine vasoconstrictor response to acute exercise that is attenuated in late pregnancy. Pregnant (P, N = 12) and nonpregnant (NP, N = 8) rats were instrumented chronically with a ultrasonic transit-time flowprobe and carotid arterial catheter to directly measure uterine artery blood flow (UtBF) and blood pressure (BP), respectively, at day 20 of gestation for 5 min of treadmill exercise (7 m/min; 6% grade). Preexercise UtBF [P, 2.1 (SD1.6) vs. NP, 0.5 (SD0.3) mL/min P < 0.01) and uterine artery conductance (UtC) [P, 2.1(SD1.7) vs. NP, 0.4 (SD0.2) mL/min × mmHg−1 × 10−2, P < 0.01] were higher in pregnant rats, whereas preexercise BP was lower in the pregnant rats [P, 111 (SD13) vs. NP, 126 (SD13) mmHg, P = 0.02]. Preexercise heart rate was similar [P, 457 (SD30) vs. NP, 454 (SD42), P = 0.3]. Exercise initiated rapid and sustained decreases in UtBF [Δ−47% (SD12)] and UtC [Δ−49% (SD12)] that were attenuated in the pregnant rats [UtBF, Δ−25% (SD20) and UtC, Δ−30% (SD20), P = 0.02]. The BP and heart rate responses to exercise were unaffected in late pregnancy (interaction term, P = 0.3). In rats, dynamic exercise induces a uterine vasoconstrictor response that is blunted during late gestation, a response that we observed previously in pregnant rabbits." @default.
- W2117429194 created "2016-06-24" @default.
- W2117429194 creator A5001253434 @default.
- W2117429194 creator A5008169198 @default.
- W2117429194 creator A5014471805 @default.
- W2117429194 creator A5037964325 @default.
- W2117429194 creator A5072991101 @default.
- W2117429194 date "2015-03-01" @default.
- W2117429194 modified "2023-09-27" @default.
- W2117429194 title "Effect of pregnancy on the uterine vasoconstrictor response to exercise in rats" @default.
- W2117429194 cites W122661615 @default.
- W2117429194 cites W1566969346 @default.
- W2117429194 cites W1966036045 @default.
- W2117429194 cites W1968360736 @default.
- W2117429194 cites W1984312907 @default.
- W2117429194 cites W1988770726 @default.
- W2117429194 cites W1989203508 @default.
- W2117429194 cites W1990184142 @default.
- W2117429194 cites W2004460893 @default.
- W2117429194 cites W2014486451 @default.
- W2117429194 cites W2016542437 @default.
- W2117429194 cites W2024277700 @default.
- W2117429194 cites W2032845384 @default.
- W2117429194 cites W2035930508 @default.
- W2117429194 cites W2042597390 @default.
- W2117429194 cites W2046784860 @default.
- W2117429194 cites W2052464660 @default.
- W2117429194 cites W2057275207 @default.
- W2117429194 cites W2057313063 @default.
- W2117429194 cites W2058227592 @default.
- W2117429194 cites W2063891196 @default.
- W2117429194 cites W2069786471 @default.
- W2117429194 cites W2073244888 @default.
- W2117429194 cites W2078156206 @default.
- W2117429194 cites W2080587290 @default.
- W2117429194 cites W2086554023 @default.
- W2117429194 cites W2097531156 @default.
- W2117429194 cites W2100108339 @default.
- W2117429194 cites W2102328645 @default.
- W2117429194 cites W2123104626 @default.
- W2117429194 cites W2124639769 @default.
- W2117429194 cites W2124899538 @default.
- W2117429194 cites W2139395599 @default.
- W2117429194 cites W2143396987 @default.
- W2117429194 cites W2149763792 @default.
- W2117429194 cites W2151389745 @default.
- W2117429194 cites W2155587127 @default.
- W2117429194 cites W2161783739 @default.
- W2117429194 cites W2164435318 @default.
- W2117429194 cites W2169139909 @default.
- W2117429194 cites W2170551672 @default.
- W2117429194 cites W2206522579 @default.
- W2117429194 cites W2215979228 @default.
- W2117429194 cites W2234785818 @default.
- W2117429194 cites W2262501216 @default.
- W2117429194 cites W2268371450 @default.
- W2117429194 cites W2269161383 @default.
- W2117429194 cites W2274028569 @default.
- W2117429194 cites W2325746420 @default.
- W2117429194 cites W2336913226 @default.
- W2117429194 cites W2345035982 @default.
- W2117429194 cites W2395463709 @default.
- W2117429194 cites W2411317300 @default.
- W2117429194 cites W2414350874 @default.
- W2117429194 cites W2416110170 @default.
- W2117429194 cites W2424820749 @default.
- W2117429194 cites W2469522916 @default.
- W2117429194 cites W4255981410 @default.
- W2117429194 cites W610983830 @default.
- W2117429194 doi "https://doi.org/10.14814/phy2.12337" @default.
- W2117429194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4393170" @default.
- W2117429194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25804264" @default.
- W2117429194 hasPublicationYear "2015" @default.
- W2117429194 type Work @default.
- W2117429194 sameAs 2117429194 @default.
- W2117429194 citedByCount "8" @default.
- W2117429194 countsByYear W21174291942015 @default.
- W2117429194 countsByYear W21174291942017 @default.
- W2117429194 countsByYear W21174291942019 @default.
- W2117429194 countsByYear W21174291942021 @default.
- W2117429194 countsByYear W21174291942022 @default.
- W2117429194 crossrefType "journal-article" @default.
- W2117429194 hasAuthorship W2117429194A5001253434 @default.
- W2117429194 hasAuthorship W2117429194A5008169198 @default.
- W2117429194 hasAuthorship W2117429194A5014471805 @default.
- W2117429194 hasAuthorship W2117429194A5037964325 @default.
- W2117429194 hasAuthorship W2117429194A5072991101 @default.
- W2117429194 hasBestOaLocation W21174291941 @default.
- W2117429194 hasConcept C126322002 @default.
- W2117429194 hasConcept C134018914 @default.
- W2117429194 hasConcept C172680121 @default.
- W2117429194 hasConcept C2777953023 @default.
- W2117429194 hasConcept C2779066055 @default.
- W2117429194 hasConcept C2779234561 @default.
- W2117429194 hasConcept C2781207646 @default.
- W2117429194 hasConcept C46973012 @default.
- W2117429194 hasConcept C54355233 @default.
- W2117429194 hasConcept C71924100 @default.