FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117447777> ?p ?o ?g. }

• W2117447777 endingPage "964.e6" @default.
• W2117447777 startingPage "964.e1" @default.
• W2117447777 abstract "To investigate the expression and distribution of phosphodiesterase (PDE) isoenzymes PDE1A, PDE2A, PDE4A, PDE4B, and PDE5A in human urethral tissue.Specimens of penile urethra were obtained from male subjects who had undergone male-to-female sex reassignment surgery. Using immunohistochemistry (immunofluorescence), the occurrence of PDE1A, PDE2A, PDE4A, PDE4B, and PDE5A, the neuronal nitric oxide synthase, calcitonin gene-related peptide, and vasoactive intestinal polypeptide was examined in urethral sections. Cytosolic supernatants prepared from isolated human urethral tissue were subjected to Western blot analysis using specific anti-PDE antibodies.Immunosignals specific for PDE1A, 4A, 4B, and 5A were observed in the urethral smooth musculature. The smooth muscle bundles were seen innervated by slender nerve fibers, characterized by the expression of the neuronal nitric oxide synthase, calcitonin gene-related peptide, and vasoactive intestinal polypeptide. The expression of the PDE isoenzymes mentioned was confirmed by Western blotting.The results provide evidence for a significance of both the cyclic adenosine monophosphate and cyclic guanosine monophosphate signaling in the control of human urethral smooth muscle. The selective inhibition of PDE isoenzymes might represent a pharmacologic option to influence the function of smooth musculature in the human outflow region." @default.
• W2117447777 created "2016-06-24" @default.
• W2117447777 creator A5041727274 @default.
• W2117447777 creator A5043068037 @default.
• W2117447777 creator A5050421886 @default.
• W2117447777 creator A5074132849 @default.
• W2117447777 creator A5080116321 @default.
• W2117447777 creator A5081261070 @default.
• W2117447777 creator A5089325412 @default.
• W2117447777 date "2015-04-01" @default.
• W2117447777 modified "2023-09-23" @default.
• W2117447777 title "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra" @default.
• W2117447777 cites W1516971631 @default.
• W2117447777 cites W1964683861 @default.
• W2117447777 cites W1968248192 @default.
• W2117447777 cites W1997669045 @default.
• W2117447777 cites W2012067681 @default.
• W2117447777 cites W2013458624 @default.
• W2117447777 cites W2015050915 @default.
• W2117447777 cites W2020345266 @default.
• W2117447777 cites W2023252283 @default.
• W2117447777 cites W2032427139 @default.
• W2117447777 cites W2046727636 @default.
• W2117447777 cites W2115613725 @default.
• W2117447777 cites W2130346500 @default.
• W2117447777 cites W2139127970 @default.
• W2117447777 cites W2254204947 @default.
• W2117447777 cites W3161709700 @default.
• W2117447777 doi "https://doi.org/10.1016/j.urology.2014.12.030" @default.
• W2117447777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25704994" @default.
• W2117447777 hasPublicationYear "2015" @default.
• W2117447777 type Work @default.
• W2117447777 sameAs 2117447777 @default.
• W2117447777 citedByCount "7" @default.
• W2117447777 countsByYear W21174477772015 @default.
• W2117447777 countsByYear W21174477772016 @default.
• W2117447777 countsByYear W21174477772018 @default.
• W2117447777 countsByYear W21174477772019 @default.
• W2117447777 countsByYear W21174477772020 @default.
• W2117447777 countsByYear W21174477772021 @default.
• W2117447777 crossrefType "journal-article" @default.
• W2117447777 hasAuthorship W2117447777A5041727274 @default.
• W2117447777 hasAuthorship W2117447777A5043068037 @default.
• W2117447777 hasAuthorship W2117447777A5050421886 @default.
• W2117447777 hasAuthorship W2117447777A5074132849 @default.
• W2117447777 hasAuthorship W2117447777A5080116321 @default.
• W2117447777 hasAuthorship W2117447777A5081261070 @default.
• W2117447777 hasAuthorship W2117447777A5089325412 @default.
• W2117447777 hasConcept C104317684 @default.
• W2117447777 hasConcept C105702510 @default.
• W2117447777 hasConcept C118303440 @default.
• W2117447777 hasConcept C119795356 @default.
• W2117447777 hasConcept C126322002 @default.
• W2117447777 hasConcept C134018914 @default.
• W2117447777 hasConcept C150194340 @default.
• W2117447777 hasConcept C163170386 @default.
• W2117447777 hasConcept C170493617 @default.
• W2117447777 hasConcept C177707886 @default.
• W2117447777 hasConcept C181199279 @default.
• W2117447777 hasConcept C204232928 @default.
• W2117447777 hasConcept C2776415932 @default.
• W2117447777 hasConcept C2776668983 @default.
• W2117447777 hasConcept C2776991684 @default.
• W2117447777 hasConcept C2777085111 @default.
• W2117447777 hasConcept C2777622882 @default.
• W2117447777 hasConcept C2779627488 @default.
• W2117447777 hasConcept C2780994212 @default.
• W2117447777 hasConcept C519581460 @default.
• W2117447777 hasConcept C55493867 @default.
• W2117447777 hasConcept C62826618 @default.
• W2117447777 hasConcept C71924100 @default.
• W2117447777 hasConcept C8330315 @default.
• W2117447777 hasConcept C85265743 @default.
• W2117447777 hasConcept C86803240 @default.
• W2117447777 hasConceptScore W2117447777C104317684 @default.
• W2117447777 hasConceptScore W2117447777C105702510 @default.
• W2117447777 hasConceptScore W2117447777C118303440 @default.
• W2117447777 hasConceptScore W2117447777C119795356 @default.
• W2117447777 hasConceptScore W2117447777C126322002 @default.
• W2117447777 hasConceptScore W2117447777C134018914 @default.
• W2117447777 hasConceptScore W2117447777C150194340 @default.
• W2117447777 hasConceptScore W2117447777C163170386 @default.
• W2117447777 hasConceptScore W2117447777C170493617 @default.
• W2117447777 hasConceptScore W2117447777C177707886 @default.
• W2117447777 hasConceptScore W2117447777C181199279 @default.
• W2117447777 hasConceptScore W2117447777C204232928 @default.
• W2117447777 hasConceptScore W2117447777C2776415932 @default.
• W2117447777 hasConceptScore W2117447777C2776668983 @default.
• W2117447777 hasConceptScore W2117447777C2776991684 @default.
• W2117447777 hasConceptScore W2117447777C2777085111 @default.
• W2117447777 hasConceptScore W2117447777C2777622882 @default.
• W2117447777 hasConceptScore W2117447777C2779627488 @default.
• W2117447777 hasConceptScore W2117447777C2780994212 @default.
• W2117447777 hasConceptScore W2117447777C519581460 @default.
• W2117447777 hasConceptScore W2117447777C55493867 @default.
• W2117447777 hasConceptScore W2117447777C62826618 @default.
• W2117447777 hasConceptScore W2117447777C71924100 @default.
• W2117447777 hasConceptScore W2117447777C8330315 @default.

• next