Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117477598> ?p ?o ?g. }
- W2117477598 endingPage "2397" @default.
- W2117477598 startingPage "2389" @default.
- W2117477598 abstract "Tumour necrosis factor (TNF) is a pleiotropic cytokine with a wide range of immunoregulatory effects. Variation in the promoter region of TNF and the neighbouring lymphotoxin alpha (LTA) gene might be associated with endometriosis.We examined the association between endometriosis and common single-nucleotide polymorphisms (SNPs) or haplotypes in the TNF/LTA region in an Australian sample by analysing 26 SNPs in 958 endometriosis cases and 959 unrelated controls. We selected functional SNPs in the coding and the promoter region of the TNF gene and HapMap tagging SNPs and typed them on a Sequenom MassARRAY platform. A key SNP (rs1800630) in the promoter region typed in previous studies did not give reliable results. Therefore, we also examined a statistically identical (r(2) = 1) SNP (siSNP) (rs2844482), identified using the web based program ssSNPer.Genotype completion rate was 99.5% for SNPs spanning a region of 15.5 kb across the TNF/LTA locus. There was no evidence for association between endometriosis and TNF/LTA SNPs or SNP haplotypes in our case-control study.Our data suggest both TNF and LTA genes are not major susceptibility genes for endometriosis." @default.
- W2117477598 created "2016-06-24" @default.
- W2117477598 creator A5007163374 @default.
- W2117477598 creator A5014281984 @default.
- W2117477598 creator A5014706177 @default.
- W2117477598 creator A5042709773 @default.
- W2117477598 creator A5052242429 @default.
- W2117477598 creator A5060726147 @default.
- W2117477598 creator A5064749062 @default.
- W2117477598 creator A5084368351 @default.
- W2117477598 date "2007-06-28" @default.
- W2117477598 modified "2023-09-27" @default.
- W2117477598 title "Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample" @default.
- W2117477598 cites W1453987920 @default.
- W2117477598 cites W1540374299 @default.
- W2117477598 cites W155846448 @default.
- W2117477598 cites W1603869185 @default.
- W2117477598 cites W1845556393 @default.
- W2117477598 cites W1968427910 @default.
- W2117477598 cites W1975548740 @default.
- W2117477598 cites W1975751977 @default.
- W2117477598 cites W1977927757 @default.
- W2117477598 cites W1978407857 @default.
- W2117477598 cites W1979363808 @default.
- W2117477598 cites W1981892938 @default.
- W2117477598 cites W1989278762 @default.
- W2117477598 cites W1991579675 @default.
- W2117477598 cites W1992372603 @default.
- W2117477598 cites W1993422257 @default.
- W2117477598 cites W2013139282 @default.
- W2117477598 cites W2019406753 @default.
- W2117477598 cites W2023102754 @default.
- W2117477598 cites W2030656664 @default.
- W2117477598 cites W2031178654 @default.
- W2117477598 cites W2031390952 @default.
- W2117477598 cites W2035261868 @default.
- W2117477598 cites W2043909203 @default.
- W2117477598 cites W2052904527 @default.
- W2117477598 cites W2054749660 @default.
- W2117477598 cites W2056382301 @default.
- W2117477598 cites W2058450394 @default.
- W2117477598 cites W2058769784 @default.
- W2117477598 cites W2059017909 @default.
- W2117477598 cites W2061542205 @default.
- W2117477598 cites W2062746747 @default.
- W2117477598 cites W2063028898 @default.
- W2117477598 cites W2074613170 @default.
- W2117477598 cites W2078073352 @default.
- W2117477598 cites W2081922436 @default.
- W2117477598 cites W2083096151 @default.
- W2117477598 cites W2084426473 @default.
- W2117477598 cites W2094882243 @default.
- W2117477598 cites W2095093944 @default.
- W2117477598 cites W2095950129 @default.
- W2117477598 cites W2097313599 @default.
- W2117477598 cites W2097396176 @default.
- W2117477598 cites W2098736824 @default.
- W2117477598 cites W2104838811 @default.
- W2117477598 cites W2105632542 @default.
- W2117477598 cites W2108178559 @default.
- W2117477598 cites W2109606512 @default.
- W2117477598 cites W2109989839 @default.
- W2117477598 cites W2110245889 @default.
- W2117477598 cites W2110821910 @default.
- W2117477598 cites W2111888974 @default.
- W2117477598 cites W2112165862 @default.
- W2117477598 cites W2118094114 @default.
- W2117477598 cites W2118170461 @default.
- W2117477598 cites W2120508672 @default.
- W2117477598 cites W2123838494 @default.
- W2117477598 cites W2126781562 @default.
- W2117477598 cites W2140615092 @default.
- W2117477598 cites W2141367788 @default.
- W2117477598 cites W2147351691 @default.
- W2117477598 cites W2148169408 @default.
- W2117477598 cites W2150548455 @default.
- W2117477598 cites W2152370637 @default.
- W2117477598 cites W2152664025 @default.
- W2117477598 cites W2156409723 @default.
- W2117477598 cites W2161247040 @default.
- W2117477598 cites W2162175917 @default.
- W2117477598 cites W2162530578 @default.
- W2117477598 cites W2164527973 @default.
- W2117477598 cites W2167412836 @default.
- W2117477598 cites W2169080417 @default.
- W2117477598 cites W2171416772 @default.
- W2117477598 cites W2181009182 @default.
- W2117477598 cites W2285800750 @default.
- W2117477598 cites W2406765481 @default.
- W2117477598 cites W2412565930 @default.
- W2117477598 cites W2412782982 @default.
- W2117477598 cites W299854676 @default.
- W2117477598 cites W98713221 @default.
- W2117477598 cites W2424639514 @default.
- W2117477598 doi "https://doi.org/10.1093/humrep/dem182" @default.
- W2117477598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17595314" @default.
- W2117477598 hasPublicationYear "2007" @default.
- W2117477598 type Work @default.