FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117490265> ?p ?o ?g. }

• W2117490265 endingPage "501" @default.
• W2117490265 startingPage "494" @default.
• W2117490265 abstract "Duchenne muscular dystrophy (DMD) is a lethal muscle disorder caused by mutations in the DMD gene for which no mutation‐targeted therapy has been available thus far. However, exon‐skipping mediated by antisense oligonucleotides (AOs), which are short single‐strand DNAs, has considerable potential for DMD therapy, and clinical trials in DMD patients are currently underway. This exon‐skipping therapy changes an out‐of‐frame mutation into an in‐frame mutation, aiming at conversion of a severe DMD phenotype into a mild phenotype by restoration of truncated dystrophin expression. Recently, stable and less‐toxic AOs have been developed, and their higher efficacy was confirmed in mice and dog models of DMD. In this review, we briefly summarize the genetic basis of DMD and the potential and perspectives of exon skipping as a promising therapy for this disease." @default.
• W2117490265 created "2016-06-24" @default.
• W2117490265 creator A5008975500 @default.
• W2117490265 creator A5074650312 @default.
• W2117490265 date "2009-07-15" @default.
• W2117490265 modified "2023-10-15" @default.
• W2117490265 title "Exon-skipping therapy for Duchenne muscular dystrophy" @default.
• W2117490265 cites W1594958231 @default.
• W2117490265 cites W1627116606 @default.
• W2117490265 cites W1963803693 @default.
• W2117490265 cites W1971377724 @default.
• W2117490265 cites W1983806612 @default.
• W2117490265 cites W1990084717 @default.
• W2117490265 cites W1992719791 @default.
• W2117490265 cites W1992867281 @default.
• W2117490265 cites W1996860050 @default.
• W2117490265 cites W1998385625 @default.
• W2117490265 cites W2008433836 @default.
• W2117490265 cites W2010757394 @default.
• W2117490265 cites W2011484654 @default.
• W2117490265 cites W2016256497 @default.
• W2117490265 cites W2022498257 @default.
• W2117490265 cites W2022736892 @default.
• W2117490265 cites W2028062434 @default.
• W2117490265 cites W2034273480 @default.
• W2117490265 cites W2035645019 @default.
• W2117490265 cites W2041137184 @default.
• W2117490265 cites W2047689734 @default.
• W2117490265 cites W2062442451 @default.
• W2117490265 cites W2063318299 @default.
• W2117490265 cites W2065834676 @default.
• W2117490265 cites W2066180106 @default.
• W2117490265 cites W2066950610 @default.
• W2117490265 cites W2083068052 @default.
• W2117490265 cites W2085811948 @default.
• W2117490265 cites W2085986454 @default.
• W2117490265 cites W2089229823 @default.
• W2117490265 cites W2090849645 @default.
• W2117490265 cites W2093794977 @default.
• W2117490265 cites W2094796370 @default.
• W2117490265 cites W2098051622 @default.
• W2117490265 cites W2098263284 @default.
• W2117490265 cites W2110154453 @default.
• W2117490265 cites W2134614924 @default.
• W2117490265 cites W2145661846 @default.
• W2117490265 cites W2149543855 @default.
• W2117490265 cites W2152060821 @default.
• W2117490265 cites W2168692744 @default.
• W2117490265 cites W2172085519 @default.
• W2117490265 doi "https://doi.org/10.1111/j.1440-1789.2009.01028.x" @default.
• W2117490265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19486303" @default.
• W2117490265 hasPublicationYear "2009" @default.
• W2117490265 type Work @default.
• W2117490265 sameAs 2117490265 @default.
• W2117490265 citedByCount "41" @default.
• W2117490265 countsByYear W21174902652012 @default.
• W2117490265 countsByYear W21174902652013 @default.
• W2117490265 countsByYear W21174902652014 @default.
• W2117490265 countsByYear W21174902652015 @default.
• W2117490265 countsByYear W21174902652016 @default.
• W2117490265 countsByYear W21174902652017 @default.
• W2117490265 countsByYear W21174902652018 @default.
• W2117490265 countsByYear W21174902652019 @default.
• W2117490265 countsByYear W21174902652020 @default.
• W2117490265 countsByYear W21174902652021 @default.
• W2117490265 countsByYear W21174902652022 @default.
• W2117490265 crossrefType "journal-article" @default.
• W2117490265 hasAuthorship W2117490265A5008975500 @default.
• W2117490265 hasAuthorship W2117490265A5074650312 @default.
• W2117490265 hasConcept C104317684 @default.
• W2117490265 hasConcept C111599444 @default.
• W2117490265 hasConcept C126322002 @default.
• W2117490265 hasConcept C127716648 @default.
• W2117490265 hasConcept C194583182 @default.
• W2117490265 hasConcept C2778776201 @default.
• W2117490265 hasConcept C2778943923 @default.
• W2117490265 hasConcept C2779030066 @default.
• W2117490265 hasConcept C2780394045 @default.
• W2117490265 hasConcept C36823959 @default.
• W2117490265 hasConcept C501734568 @default.
• W2117490265 hasConcept C54355233 @default.
• W2117490265 hasConcept C60644358 @default.
• W2117490265 hasConcept C71924100 @default.
• W2117490265 hasConcept C86803240 @default.
• W2117490265 hasConceptScore W2117490265C104317684 @default.
• W2117490265 hasConceptScore W2117490265C111599444 @default.
• W2117490265 hasConceptScore W2117490265C126322002 @default.
• W2117490265 hasConceptScore W2117490265C127716648 @default.
• W2117490265 hasConceptScore W2117490265C194583182 @default.
• W2117490265 hasConceptScore W2117490265C2778776201 @default.
• W2117490265 hasConceptScore W2117490265C2778943923 @default.
• W2117490265 hasConceptScore W2117490265C2779030066 @default.
• W2117490265 hasConceptScore W2117490265C2780394045 @default.
• W2117490265 hasConceptScore W2117490265C36823959 @default.
• W2117490265 hasConceptScore W2117490265C501734568 @default.
• W2117490265 hasConceptScore W2117490265C54355233 @default.
• W2117490265 hasConceptScore W2117490265C60644358 @default.
• W2117490265 hasConceptScore W2117490265C71924100 @default.

• next