FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117524741> ?p ?o ?g. }

• W2117524741 endingPage "1753" @default.
• W2117524741 startingPage "1746" @default.
• W2117524741 abstract "In contrast to the hsp70 gene, whose expression is normally at a very low level and increases by more than 2 orders of magnitude during heat shock, the hsp83 gene in Drosophila melanogaster is expressed at high levels during normal development and increases only severalfold in response to heat shock. Developmental expression of the hsp83 gene consists of a high level of tissue-general, basal expression and a very high level of expression in ovaries. We identified regions upstream of the hsp83 gene that were required for its developmental and heat shock-induced expression by assaying beta-galactosidase activity and mRNA levels in transgenic animals containing a series of 5' deletion and insertion mutations of an hsp83-lacZ fusion gene. Deletion of sequences upstream of the overlapping array of a previously defined heat shock consensus (HSC) sequence eliminated both forms of developmental expression of the hsp83 gene. As a result, the hsp83 gene with this deletion mutation was regulated like that of the hsp70 gene. Moreover, an in vivo polymer competition assay revealed that the overlapping HSC sequences of the hsp83 gene and the nonoverlapping HSC sequences of the hsp70 gene had similar affinities for the factor required for heat induction of the two heat shock genes. We discuss the functional similarity of hsp70 and hsp83 heat shock regulation in terms of a revised view of the heat shock-regulatory sequence." @default.
• W2117524741 created "2016-06-24" @default.
• W2117524741 creator A5016053889 @default.
• W2117524741 creator A5060183257 @default.
• W2117524741 date "1989-04-01" @default.
• W2117524741 modified "2023-10-11" @default.
• W2117524741 title "Heat shock and developmental regulation of the Drosophila melanogaster hsp83 gene." @default.
• W2117524741 cites W1433025566 @default.
• W2117524741 cites W1487747051 @default.
• W2117524741 cites W1871616970 @default.
• W2117524741 cites W1949490448 @default.
• W2117524741 cites W1955892023 @default.
• W2117524741 cites W1968102722 @default.
• W2117524741 cites W1976296304 @default.
• W2117524741 cites W1988198388 @default.
• W2117524741 cites W1994528729 @default.
• W2117524741 cites W1999382048 @default.
• W2117524741 cites W2001369720 @default.
• W2117524741 cites W2008651229 @default.
• W2117524741 cites W2009968835 @default.
• W2117524741 cites W2012015460 @default.
• W2117524741 cites W2018184392 @default.
• W2117524741 cites W2019273140 @default.
• W2117524741 cites W2019486354 @default.
• W2117524741 cites W2019542866 @default.
• W2117524741 cites W2024113281 @default.
• W2117524741 cites W2025060557 @default.
• W2117524741 cites W2042543706 @default.
• W2117524741 cites W2048213411 @default.
• W2117524741 cites W2056463259 @default.
• W2117524741 cites W2063450941 @default.
• W2117524741 cites W2077165667 @default.
• W2117524741 cites W2078481082 @default.
• W2117524741 cites W2080024031 @default.
• W2117524741 cites W2080567269 @default.
• W2117524741 cites W2089240756 @default.
• W2117524741 cites W2109664605 @default.
• W2117524741 cites W2112638355 @default.
• W2117524741 cites W2144634347 @default.
• W2117524741 cites W2147102123 @default.
• W2117524741 cites W2159271990 @default.
• W2117524741 cites W2165113979 @default.
• W2117524741 cites W2169058508 @default.
• W2117524741 cites W2179349974 @default.
• W2117524741 cites W2216688057 @default.
• W2117524741 cites W2262431368 @default.
• W2117524741 cites W35142187 @default.
• W2117524741 cites W64551962 @default.
• W2117524741 doi "https://doi.org/10.1128/mcb.9.4.1746" @default.
• W2117524741 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/362593" @default.
• W2117524741 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2471067" @default.
• W2117524741 hasPublicationYear "1989" @default.
• W2117524741 type Work @default.
• W2117524741 sameAs 2117524741 @default.
• W2117524741 citedByCount "78" @default.
• W2117524741 countsByYear W21175247412012 @default.
• W2117524741 countsByYear W21175247412013 @default.
• W2117524741 countsByYear W21175247412014 @default.
• W2117524741 countsByYear W21175247412016 @default.
• W2117524741 countsByYear W21175247412017 @default.
• W2117524741 countsByYear W21175247412018 @default.
• W2117524741 countsByYear W21175247412019 @default.
• W2117524741 countsByYear W21175247412020 @default.
• W2117524741 countsByYear W21175247412022 @default.
• W2117524741 countsByYear W21175247412023 @default.
• W2117524741 crossrefType "journal-article" @default.
• W2117524741 hasAuthorship W2117524741A5016053889 @default.
• W2117524741 hasAuthorship W2117524741A5060183257 @default.
• W2117524741 hasBestOaLocation W21175247411 @default.
• W2117524741 hasConcept C102230213 @default.
• W2117524741 hasConcept C103474985 @default.
• W2117524741 hasConcept C104317684 @default.
• W2117524741 hasConcept C111829193 @default.
• W2117524741 hasConcept C137984847 @default.
• W2117524741 hasConcept C150194340 @default.
• W2117524741 hasConcept C153911025 @default.
• W2117524741 hasConcept C165864922 @default.
• W2117524741 hasConcept C205260736 @default.
• W2117524741 hasConcept C21592294 @default.
• W2117524741 hasConcept C2777379243 @default.
• W2117524741 hasConcept C2780104201 @default.
• W2117524741 hasConcept C52981337 @default.
• W2117524741 hasConcept C54355233 @default.
• W2117524741 hasConcept C68991219 @default.
• W2117524741 hasConcept C86803240 @default.
• W2117524741 hasConceptScore W2117524741C102230213 @default.
• W2117524741 hasConceptScore W2117524741C103474985 @default.
• W2117524741 hasConceptScore W2117524741C104317684 @default.
• W2117524741 hasConceptScore W2117524741C111829193 @default.
• W2117524741 hasConceptScore W2117524741C137984847 @default.
• W2117524741 hasConceptScore W2117524741C150194340 @default.
• W2117524741 hasConceptScore W2117524741C153911025 @default.
• W2117524741 hasConceptScore W2117524741C165864922 @default.
• W2117524741 hasConceptScore W2117524741C205260736 @default.
• W2117524741 hasConceptScore W2117524741C21592294 @default.
• W2117524741 hasConceptScore W2117524741C2777379243 @default.
• W2117524741 hasConceptScore W2117524741C2780104201 @default.
• W2117524741 hasConceptScore W2117524741C52981337 @default.

• next