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- W2117569785 abstract "In a recent issue of Annals, Lee et al1Lee J. Kirschner J. Pawa S. et al.Computed tomography use in the adult emergency department of an academic urban hospital from 2001 to 2007.Ann Emerg Med. 2010; 56: 591-596Abstract Full Text Full Text PDF PubMed Scopus (95) Google Scholar provides important information on the rate of computed tomography (CT) use in an academic emergency department (ED) and thoughtfully discuss the implications for carcinogenesis. I applaud their efforts to describe medical ionizing radiation exposures in the ED and to relate these to subsequent cancer risk. They nicely describe some uncertainties of risk assessment and place the risk from CT into context, emphasizing that the generally agreed-on risks are small. However, I believe their discussion may confuse readers about 2 features of risk associated with ionizing radiation exposure. First, Lee et al state that “radiation sensitivity and potential risk of cancer generally persist into adulthood, approximately until the age of 35 years,” citing work by Brenner and Hall.2Brenner D.J. Hall E.J. Computed tomography—an increasing source of radiation exposure.N Engl J Med. 2007; 357: 2277-2284Crossref PubMed Scopus (6394) Google Scholar Brenner and Hall's estimates of attributable mortality risk from medical radiation exposures do not suggest an upper age limit to radiation sensitivity; rather, they suggest that the attributable mortality risk from a single exposure plateaus but persists for exposures occurring after approximately age 35 years.2Brenner D.J. Hall E.J. Computed tomography—an increasing source of radiation exposure.N Engl J Med. 2007; 357: 2277-2284Crossref PubMed Scopus (6394) Google Scholar Although the attributable cancer risk from a single radiation exposure in older adults is small, the cumulative effects of multiple exposures over time should be considered because adults remain susceptible.3Griffey R.T. Sodickson A. Cumulative radiation exposure and cancer risk estimates in emergency department patients undergoing repeat or multiple CT.AJR Am J Roentgenol. 2009; 192: 887-892Crossref PubMed Scopus (169) Google Scholar Second, Lee et al describe that “the radiation dose from one CT [is] well within the range for increased cancer risk and increased mortality.”2Brenner D.J. Hall E.J. Computed tomography—an increasing source of radiation exposure.N Engl J Med. 2007; 357: 2277-2284Crossref PubMed Scopus (6394) Google Scholar This statement suggests that a threshold for carcinogenesis exists and that a safe level of exposure could be defined, below which no risk occurs. However, the model of radiation-related carcinogenesis endorsed by the National Academies in the Biological Effects of Ionizing Radiation VII report is the “linear-no-threshold” model.4Committee to Assess the Health Risks From Exposure to Low Levels of Ionizing Radiation; National Research Council (US)Health Risks From Exposure to Low Levels of Ionizing Radiation: BEIR VII, Phase 2. Washington, DC, 2006Google Scholar As the name implies, this model holds that no safe threshold exists and that a linear risk continues even with very low exposures. The importance of this to emergency physicians and their patients is that low exposures, although making a small contribution to cancer risk, cannot be discounted entirely and should be considered in the overall risk:benefit decision for each patient. Although it may be convenient shorthand in discussions with patients to describe a given radiation exposure as “safe,” it does not accurately depict the current scientific consensus. Competing theories for radiation carcinogenesis, including one that hypothesizes low-level exposures to be protective, are not endorsed by the National Academies.4Committee to Assess the Health Risks From Exposure to Low Levels of Ionizing Radiation; National Research Council (US)Health Risks From Exposure to Low Levels of Ionizing Radiation: BEIR VII, Phase 2. Washington, DC, 2006Google Scholar Emergency physicians must have an awareness and sophisticated understanding of the risks associated with diagnostic radiation. Patients will benefit most when physicians neither over- nor underestimate risks. Computed Tomography Use in the Adult Emergency Department of an Academic Urban Hospital From 2001 to 2007Annals of Emergency MedicineVol. 56Issue 6PreviewThere is both increasing recognition and growing scrutiny of the increased utilization of computed tomography (CT) in medicine. For our primary objective, we determine and quantify the CT utilization rate in our emergency department (ED) during the last 7 years. As a secondary objective, we compare trends in utilization for various types of CT scans. Full-Text PDF In replyAnnals of Emergency MedicineVol. 57Issue 3PreviewWe appreciate all the comments from Dr. Broder. The clarifications are helpful, and we agree wholeheartedly with the importance of emergency physicians being more thoughtful about radiation exposure to patients. As evidenced by our study and a number of others in the recent literature, emergency physicians are using and relying on imaging technology more than ever before. For the sake of our patients, we must consider not only the many benefits but also the risks. Full-Text PDF" @default.
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- W2117569785 title "Radiation Risks From Diagnostic Computed Tomography in the Emergency Department" @default.
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- W2117569785 doi "https://doi.org/10.1016/j.annemergmed.2010.09.022" @default.
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