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• W2117624973 startingPage "470" @default.
• W2117624973 abstract "Tendons are dense, fibrous connective tissues that are responsible for transmitting mechanical forces from skeletal muscle to bone. From a clinical perspective, tendinopathy (defined as a syndrome of tendon pain, tenderness and swelling that affects function) is very common, both within the sporting arena and in the workplace. Importantly, proteoglycans are essential components of the tendon extracellular matrix (ECM) and changes in their expression and metabolism/turnover have been associated with tendinopathy. Within tendons, the small leucine-rich proteoglycans (SLPRs), decorin, fibromodulin, lumican and keratocan predominate within tensional regions, while in tendon fibrocartilage, increased concentrations of proteoglycans common to the articular cartilage phenotype are present, including aggrecan, biglycan and proteoglycan 4. However, the rate of proteoglycan turnover within tendon is markedly higher than that of cartilage, mediated via the “aggrecanases,” which are constitutively active in the tendon matrix. Data suggest that this increased proteoglycan turnover is likely to be required to maintain normal tendon homeostasis, with perturbations in proteoglycan metabolism contributing to tissue dysfunction. Thus, future studies aimed at furthering our fundamental knowledge of tendon proteoglycan metabolism in health and disease are important in the development of improved treatments for tendon disorders." @default.
• W2117624973 created "2016-06-24" @default.
• W2117624973 creator A5006447462 @default.
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• W2117624973 date "2009-08-01" @default.
• W2117624973 modified "2023-09-24" @default.
• W2117624973 title "Metabolism of proteoglycans in tendon" @default.
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• W2117624973 cites W1558943498 @default.
• W2117624973 cites W1580797189 @default.
• W2117624973 cites W1667085792 @default.
• W2117624973 cites W1895946034 @default.
• W2117624973 cites W192842500 @default.
• W2117624973 cites W1970572008 @default.
• W2117624973 cites W1974828804 @default.
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• W2117624973 cites W1990008900 @default.
• W2117624973 cites W1990677902 @default.
• W2117624973 cites W1991675109 @default.
• W2117624973 cites W1993316980 @default.
• W2117624973 cites W1994659756 @default.
• W2117624973 cites W1997927100 @default.
• W2117624973 cites W1998884693 @default.
• W2117624973 cites W2001344856 @default.
• W2117624973 cites W2002509647 @default.
• W2117624973 cites W2006213750 @default.
• W2117624973 cites W2009292693 @default.
• W2117624973 cites W2014269839 @default.
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• W2117624973 cites W2022812881 @default.
• W2117624973 cites W2028277256 @default.
• W2117624973 cites W2030246164 @default.
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• W2117624973 cites W2033677211 @default.
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• W2117624973 cites W2054159938 @default.
• W2117624973 cites W2055972025 @default.
• W2117624973 cites W2057896496 @default.
• W2117624973 cites W2064944758 @default.
• W2117624973 cites W2066258997 @default.
• W2117624973 cites W2066728562 @default.
• W2117624973 cites W2070013317 @default.
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• W2117624973 cites W2150236653 @default.
• W2117624973 cites W2151621078 @default.
• W2117624973 cites W2153461264 @default.
• W2117624973 cites W2154390735 @default.
• W2117624973 cites W2155323644 @default.
• W2117624973 cites W2156763800 @default.
• W2117624973 cites W2157467821 @default.
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• W2117624973 doi "https://doi.org/10.1111/j.1600-0838.2009.00938.x" @default.
• W2117624973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19422635" @default.
• W2117624973 hasPublicationYear "2009" @default.
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