FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117630424> ?p ?o ?g. }

• W2117630424 endingPage "L147" @default.
• W2117630424 startingPage "L139" @default.
• W2117630424 abstract "Prenatal ethanol exposure increases collagen deposition and alters surfactant protein (SP) expression and immune status in lungs of near-term fetal sheep. Our objectives were to determine 1) whether these prenatal effects of repeated gestational ethanol exposure persist after birth and 2) whether surfactant phospholipid composition is altered following prenatal ethanol exposure. Pregnant ewes were chronically catheterized at 90 days of gestational age (DGA) and given a 1-h daily infusion of ethanol (0.75 g/kg, n = 9) or saline ( n = 7) from 95 to 135 DGA; ethanol administration ceased after 135 DGA. Lambs were born naturally at full term (146 ± 0.5 DGA). Lung tissue was examined at 9 wk postnatal age for alterations in structure, SP expression, and inflammation; bronchoalveolar lavage fluid was examined for alterations in surfactant phospholipid composition. At 134 DGA, surfactant phospholipid concentration in amniotic fluid was significantly reduced ( P < 0.05) by ethanol exposure, and the composition was altered. In postnatal lambs, there were no significant differences between treatment groups in birth weight, postnatal growth, blood gas parameters, and lung weight, volume, tissue fraction, mean linear intercept, collagen content, proinflammatory cytokine gene expression, and bronchoalveolar lavage fluid surfactant phospholipid composition. Although SP-A, SP-B, and SP-C mRNA levels were not significantly different between treatment groups, SP-D mRNA levels were significantly greater ( P < 0.05) in ethanol-treated animals; as SP-D has immunomodulatory roles, innate immunity may be altered. The adverse effects of daily ethanol exposure during late gestation on the fetal lung do not persist to 2 mo after birth, indicating that the developing lung is capable of repair." @default.
• W2117630424 created "2016-06-24" @default.
• W2117630424 creator A5010188514 @default.
• W2117630424 creator A5025940519 @default.
• W2117630424 creator A5026217744 @default.
• W2117630424 creator A5031693224 @default.
• W2117630424 creator A5038738550 @default.
• W2117630424 creator A5045451689 @default.
• W2117630424 creator A5056580928 @default.
• W2117630424 creator A5086923376 @default.
• W2117630424 creator A5087250475 @default.
• W2117630424 creator A5087502351 @default.
• W2117630424 date "2011-01-01" @default.
• W2117630424 modified "2023-10-01" @default.
• W2117630424 title "Effects of prenatal ethanol exposure on the lungs of postnatal lambs" @default.
• W2117630424 cites W1725804876 @default.
• W2117630424 cites W1759556627 @default.
• W2117630424 cites W1861035746 @default.
• W2117630424 cites W1970334770 @default.
• W2117630424 cites W1973076790 @default.
• W2117630424 cites W1976192406 @default.
• W2117630424 cites W1979349993 @default.
• W2117630424 cites W1994375510 @default.
• W2117630424 cites W1995888662 @default.
• W2117630424 cites W1998174651 @default.
• W2117630424 cites W2000071831 @default.
• W2117630424 cites W2001214757 @default.
• W2117630424 cites W2004732671 @default.
• W2117630424 cites W2004903962 @default.
• W2117630424 cites W2016995746 @default.
• W2117630424 cites W2024667007 @default.
• W2117630424 cites W2026455557 @default.
• W2117630424 cites W2029160589 @default.
• W2117630424 cites W2042207199 @default.
• W2117630424 cites W2043114730 @default.
• W2117630424 cites W2050906980 @default.
• W2117630424 cites W2052603928 @default.
• W2117630424 cites W2056711257 @default.
• W2117630424 cites W2059453466 @default.
• W2117630424 cites W2066072238 @default.
• W2117630424 cites W2069604128 @default.
• W2117630424 cites W2079525293 @default.
• W2117630424 cites W2079756474 @default.
• W2117630424 cites W2089571230 @default.
• W2117630424 cites W2093489232 @default.
• W2117630424 cites W2099768219 @default.
• W2117630424 cites W2119040178 @default.
• W2117630424 cites W2132895437 @default.
• W2117630424 cites W2151320720 @default.
• W2117630424 cites W2158884587 @default.
• W2117630424 cites W2161157806 @default.
• W2117630424 cites W2275293999 @default.
• W2117630424 cites W2398992563 @default.
• W2117630424 cites W2417049436 @default.
• W2117630424 cites W4248065725 @default.
• W2117630424 cites W51804427 @default.
• W2117630424 doi "https://doi.org/10.1152/ajplung.00195.2010" @default.
• W2117630424 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3023283" @default.
• W2117630424 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21036920" @default.
• W2117630424 hasPublicationYear "2011" @default.
• W2117630424 type Work @default.
• W2117630424 sameAs 2117630424 @default.
• W2117630424 citedByCount "23" @default.
• W2117630424 countsByYear W21176304242012 @default.
• W2117630424 countsByYear W21176304242013 @default.
• W2117630424 countsByYear W21176304242014 @default.
• W2117630424 countsByYear W21176304242015 @default.
• W2117630424 countsByYear W21176304242016 @default.
• W2117630424 countsByYear W21176304242017 @default.
• W2117630424 crossrefType "journal-article" @default.
• W2117630424 hasAuthorship W2117630424A5010188514 @default.
• W2117630424 hasAuthorship W2117630424A5025940519 @default.
• W2117630424 hasAuthorship W2117630424A5026217744 @default.
• W2117630424 hasAuthorship W2117630424A5031693224 @default.
• W2117630424 hasAuthorship W2117630424A5038738550 @default.
• W2117630424 hasAuthorship W2117630424A5045451689 @default.
• W2117630424 hasAuthorship W2117630424A5056580928 @default.
• W2117630424 hasAuthorship W2117630424A5086923376 @default.
• W2117630424 hasAuthorship W2117630424A5087250475 @default.
• W2117630424 hasAuthorship W2117630424A5087502351 @default.
• W2117630424 hasBestOaLocation W21176304242 @default.
• W2117630424 hasConcept C126322002 @default.
• W2117630424 hasConcept C134018914 @default.
• W2117630424 hasConcept C16685009 @default.
• W2117630424 hasConcept C172680121 @default.
• W2117630424 hasConcept C185592680 @default.
• W2117630424 hasConcept C2777714996 @default.
• W2117630424 hasConcept C2777961210 @default.
• W2117630424 hasConcept C2778194526 @default.
• W2117630424 hasConcept C2778918659 @default.
• W2117630424 hasConcept C2779234561 @default.
• W2117630424 hasConcept C41625074 @default.
• W2117630424 hasConcept C46973012 @default.
• W2117630424 hasConcept C54355233 @default.
• W2117630424 hasConcept C55493867 @default.
• W2117630424 hasConcept C58226133 @default.
• W2117630424 hasConcept C71924100 @default.
• W2117630424 hasConcept C86803240 @default.

• next