Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117672162> ?p ?o ?g. }
- W2117672162 endingPage "456" @default.
- W2117672162 startingPage "450" @default.
- W2117672162 abstract "Specific chemicals can prime the plant immune system for augmented defense. β-aminobutyric acid (BABA) is a priming agent that provides broad-spectrum disease protection. However, BABA also suppresses plant growth when applied in high doses, which has hampered its application as a crop defense activator. Here we describe a mutant of Arabidopsis thaliana that is impaired in BABA-induced disease immunity (ibi1) but is hypersensitive to BABA-induced growth repression. IBI1 encodes an aspartyl-tRNA synthetase. Enantiomer-specific binding of the R enantiomer of BABA to IBI1 primed the protein for noncanonical defense signaling in the cytoplasm after pathogen attack. This priming was associated with aspartic acid accumulation and tRNA-induced phosphorylation of translation initiation factor eIF2α. However, mutation of eIF2α-phosphorylating GCN2 kinase did not affect BABA-induced immunity but relieved BABA-induced growth repression. Hence, BABA-activated IBI1 controls plant immunity and growth via separate pathways. Our results open new opportunities to separate broad-spectrum disease resistance from the associated costs on plant growth." @default.
- W2117672162 created "2016-06-24" @default.
- W2117672162 creator A5002986834 @default.
- W2117672162 creator A5014351026 @default.
- W2117672162 creator A5020099630 @default.
- W2117672162 creator A5024960063 @default.
- W2117672162 creator A5025578515 @default.
- W2117672162 creator A5038302656 @default.
- W2117672162 creator A5041375820 @default.
- W2117672162 creator A5046674673 @default.
- W2117672162 creator A5054252220 @default.
- W2117672162 creator A5070193035 @default.
- W2117672162 creator A5071672311 @default.
- W2117672162 creator A5077756582 @default.
- W2117672162 creator A5079691335 @default.
- W2117672162 date "2014-04-28" @default.
- W2117672162 modified "2023-10-01" @default.
- W2117672162 title "Plant perception of β-aminobutyric acid is mediated by an aspartyl-tRNA synthetase" @default.
- W2117672162 cites W1239683436 @default.
- W2117672162 cites W1550225859 @default.
- W2117672162 cites W1557521720 @default.
- W2117672162 cites W1559903108 @default.
- W2117672162 cites W1920908115 @default.
- W2117672162 cites W1950941644 @default.
- W2117672162 cites W1978661900 @default.
- W2117672162 cites W1984668822 @default.
- W2117672162 cites W1987003587 @default.
- W2117672162 cites W2003623249 @default.
- W2117672162 cites W2018921016 @default.
- W2117672162 cites W2032588064 @default.
- W2117672162 cites W2032879466 @default.
- W2117672162 cites W2050299992 @default.
- W2117672162 cites W2050988968 @default.
- W2117672162 cites W2052676309 @default.
- W2117672162 cites W2069400421 @default.
- W2117672162 cites W2071647949 @default.
- W2117672162 cites W2072676978 @default.
- W2117672162 cites W2076018192 @default.
- W2117672162 cites W2081155164 @default.
- W2117672162 cites W2085448694 @default.
- W2117672162 cites W2086491289 @default.
- W2117672162 cites W2093477607 @default.
- W2117672162 cites W2098101457 @default.
- W2117672162 cites W2098445557 @default.
- W2117672162 cites W2104349253 @default.
- W2117672162 cites W2104824386 @default.
- W2117672162 cites W2116122104 @default.
- W2117672162 cites W2119412408 @default.
- W2117672162 cites W2119903492 @default.
- W2117672162 cites W2121572451 @default.
- W2117672162 cites W2133571293 @default.
- W2117672162 cites W2135487705 @default.
- W2117672162 cites W2140270616 @default.
- W2117672162 cites W2141429272 @default.
- W2117672162 cites W2143406295 @default.
- W2117672162 cites W2143983383 @default.
- W2117672162 cites W2148168088 @default.
- W2117672162 cites W2149836952 @default.
- W2117672162 cites W2151264346 @default.
- W2117672162 cites W2152002992 @default.
- W2117672162 cites W2152788853 @default.
- W2117672162 cites W2153477076 @default.
- W2117672162 cites W2155246535 @default.
- W2117672162 cites W2156053468 @default.
- W2117672162 cites W2165594421 @default.
- W2117672162 cites W2166069861 @default.
- W2117672162 cites W2168001171 @default.
- W2117672162 cites W2171788269 @default.
- W2117672162 cites W2318010841 @default.
- W2117672162 cites W3080215077 @default.
- W2117672162 cites W4241689729 @default.
- W2117672162 doi "https://doi.org/10.1038/nchembio.1520" @default.
- W2117672162 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4028204" @default.
- W2117672162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24776930" @default.
- W2117672162 hasPublicationYear "2014" @default.
- W2117672162 type Work @default.
- W2117672162 sameAs 2117672162 @default.
- W2117672162 citedByCount "126" @default.
- W2117672162 countsByYear W21176721622014 @default.
- W2117672162 countsByYear W21176721622015 @default.
- W2117672162 countsByYear W21176721622016 @default.
- W2117672162 countsByYear W21176721622017 @default.
- W2117672162 countsByYear W21176721622018 @default.
- W2117672162 countsByYear W21176721622019 @default.
- W2117672162 countsByYear W21176721622020 @default.
- W2117672162 countsByYear W21176721622021 @default.
- W2117672162 countsByYear W21176721622022 @default.
- W2117672162 countsByYear W21176721622023 @default.
- W2117672162 crossrefType "journal-article" @default.
- W2117672162 hasAuthorship W2117672162A5002986834 @default.
- W2117672162 hasAuthorship W2117672162A5014351026 @default.
- W2117672162 hasAuthorship W2117672162A5020099630 @default.
- W2117672162 hasAuthorship W2117672162A5024960063 @default.
- W2117672162 hasAuthorship W2117672162A5025578515 @default.
- W2117672162 hasAuthorship W2117672162A5038302656 @default.
- W2117672162 hasAuthorship W2117672162A5041375820 @default.
- W2117672162 hasAuthorship W2117672162A5046674673 @default.
- W2117672162 hasAuthorship W2117672162A5054252220 @default.