FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117673436> ?p ?o ?g. }

• W2117673436 endingPage "592" @default.
• W2117673436 startingPage "587" @default.
• W2117673436 abstract "Summary Major surgery in persons with haemophilia A and inhibitors is increasingly being performed. Both recombinant activated factor VII ( rFVII a) and activated prothrombin complex concentrate ( APCC ) are used to cover surgery but it remains unclear what the optimal dosing schedules are. We describe the use of a hybrid regimen in four inhibitor patients undergoing eight major surgical procedures using rFVII a in the initial 2–6 postoperative days followed by FEIBA ® for the remaining period. All patients were also treated with tranexamic acid while receiving rFVII a. We performed six major orthopaedic procedures, one emergency orchidectomy and one open appendectomy. The dosing schedules were at the higher end of those described in the literature but within the recommendations of the summary of product characteristics. Despite this, we encountered non‐surgical bleeding in four of eight episodes. Three of these occurred in one individual suggesting a patient factor. The overall outcome was good for all episodes. The hybrid regimen combines flexibility of dose and dosing frequency of rFVII a in the immediate postoperative setting with the advantage of a reduced dosing frequency with FEIBA ® in the subsequent days. This study also emphasizes that surgical procedures in this patient group remain a challenge." @default.
• W2117673436 created "2016-06-24" @default.
• W2117673436 creator A5018201908 @default.
• W2117673436 creator A5034546647 @default.
• W2117673436 creator A5046783421 @default.
• W2117673436 creator A5052873285 @default.
• W2117673436 creator A5063340633 @default.
• W2117673436 date "2014-02-11" @default.
• W2117673436 modified "2023-10-01" @default.
• W2117673436 title "Major surgery in severe haemophilia A with inhibitors using a recombinant factor VIIa and activated prothrombin complex concentrate hybrid regimen" @default.
• W2117673436 cites W1541829031 @default.
• W2117673436 cites W1589374174 @default.
• W2117673436 cites W1931952713 @default.
• W2117673436 cites W1954616286 @default.
• W2117673436 cites W1965760274 @default.
• W2117673436 cites W1974712886 @default.
• W2117673436 cites W1974914214 @default.
• W2117673436 cites W1981344254 @default.
• W2117673436 cites W1988157165 @default.
• W2117673436 cites W2000305246 @default.
• W2117673436 cites W2001506642 @default.
• W2117673436 cites W2008948236 @default.
• W2117673436 cites W2016955317 @default.
• W2117673436 cites W2018451693 @default.
• W2117673436 cites W2043566164 @default.
• W2117673436 cites W2045055421 @default.
• W2117673436 cites W2048435158 @default.
• W2117673436 cites W2051935188 @default.
• W2117673436 cites W2055450420 @default.
• W2117673436 cites W2061024262 @default.
• W2117673436 cites W2074602623 @default.
• W2117673436 cites W2081847102 @default.
• W2117673436 cites W2087783598 @default.
• W2117673436 cites W2098951552 @default.
• W2117673436 cites W2110834037 @default.
• W2117673436 cites W2123764760 @default.
• W2117673436 cites W2137653703 @default.
• W2117673436 cites W2148093289 @default.
• W2117673436 cites W2156626655 @default.
• W2117673436 cites W2162535497 @default.
• W2117673436 cites W4234858608 @default.
• W2117673436 doi "https://doi.org/10.1111/hae.12365" @default.
• W2117673436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24517157" @default.
• W2117673436 hasPublicationYear "2014" @default.
• W2117673436 type Work @default.
• W2117673436 sameAs 2117673436 @default.
• W2117673436 citedByCount "11" @default.
• W2117673436 countsByYear W21176734362016 @default.
• W2117673436 countsByYear W21176734362017 @default.
• W2117673436 countsByYear W21176734362018 @default.
• W2117673436 countsByYear W21176734362019 @default.
• W2117673436 countsByYear W21176734362020 @default.
• W2117673436 countsByYear W21176734362021 @default.
• W2117673436 countsByYear W21176734362022 @default.
• W2117673436 crossrefType "journal-article" @default.
• W2117673436 hasAuthorship W2117673436A5018201908 @default.
• W2117673436 hasAuthorship W2117673436A5034546647 @default.
• W2117673436 hasAuthorship W2117673436A5046783421 @default.
• W2117673436 hasAuthorship W2117673436A5052873285 @default.
• W2117673436 hasAuthorship W2117673436A5063340633 @default.
• W2117673436 hasConcept C126322002 @default.
• W2117673436 hasConcept C141071460 @default.
• W2117673436 hasConcept C186738567 @default.
• W2117673436 hasConcept C2776301958 @default.
• W2117673436 hasConcept C2777091921 @default.
• W2117673436 hasConcept C2777232031 @default.
• W2117673436 hasConcept C2777288759 @default.
• W2117673436 hasConcept C2778382381 @default.
• W2117673436 hasConcept C2778385053 @default.
• W2117673436 hasConcept C2778961111 @default.
• W2117673436 hasConcept C2779161974 @default.
• W2117673436 hasConcept C2779637338 @default.
• W2117673436 hasConcept C2781413609 @default.
• W2117673436 hasConcept C2908626413 @default.
• W2117673436 hasConcept C2909974469 @default.
• W2117673436 hasConcept C2991743468 @default.
• W2117673436 hasConcept C42219234 @default.
• W2117673436 hasConcept C71924100 @default.
• W2117673436 hasConceptScore W2117673436C126322002 @default.
• W2117673436 hasConceptScore W2117673436C141071460 @default.
• W2117673436 hasConceptScore W2117673436C186738567 @default.
• W2117673436 hasConceptScore W2117673436C2776301958 @default.
• W2117673436 hasConceptScore W2117673436C2777091921 @default.
• W2117673436 hasConceptScore W2117673436C2777232031 @default.
• W2117673436 hasConceptScore W2117673436C2777288759 @default.
• W2117673436 hasConceptScore W2117673436C2778382381 @default.
• W2117673436 hasConceptScore W2117673436C2778385053 @default.
• W2117673436 hasConceptScore W2117673436C2778961111 @default.
• W2117673436 hasConceptScore W2117673436C2779161974 @default.
• W2117673436 hasConceptScore W2117673436C2779637338 @default.
• W2117673436 hasConceptScore W2117673436C2781413609 @default.
• W2117673436 hasConceptScore W2117673436C2908626413 @default.
• W2117673436 hasConceptScore W2117673436C2909974469 @default.
• W2117673436 hasConceptScore W2117673436C2991743468 @default.
• W2117673436 hasConceptScore W2117673436C42219234 @default.
• W2117673436 hasConceptScore W2117673436C71924100 @default.
• W2117673436 hasIssue "4" @default.
• W2117673436 hasLocation W21176734361 @default.

• next