Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117702958> ?p ?o ?g. }
- W2117702958 endingPage "606" @default.
- W2117702958 startingPage "601" @default.
- W2117702958 abstract "While it is known that non-steroidal anti-inflammatory drugs including selective cyclooxygenase-2 (COX-2) inhibitors influence BP, the exact relationship and underlying mechanisms are still unclear. We investigated the effect of etoricoxib, a selective COX-2 inhibitor on the antihypertensive efficacy of atenolol; beta-blocker, ramipril; angiotensin converting enzyme inhibitor and telmisartan; angiotensin receptor blocker in deoxycorticosterone acetate (DOCA)-salt hypertensive rats, a mineralocorticoid volume expansion model. Etoricoxib attenuated the antihypertensive-induced reduction of systolic (atenolol; P < .001, ramipril; P = .011, telmisartan; P = .003) and mean arterial pressure (atenolol; P < .001, ramipril; P = .032, telmisartan; P = .023). These results demonstrate that COX-2 dependent mechanisms play a significant role in blood pressure regulation, and etoricoxib-induced COX-2 inhibition blunts the therapeutic effect of different classes of antihypertensives in this mineralocorticoid volume expansion model of hypertension." @default.
- W2117702958 created "2016-06-24" @default.
- W2117702958 creator A5019131029 @default.
- W2117702958 creator A5029193472 @default.
- W2117702958 creator A5080016287 @default.
- W2117702958 creator A5080942991 @default.
- W2117702958 date "2013-03-14" @default.
- W2117702958 modified "2023-10-05" @default.
- W2117702958 title "Etoricoxib Attenuates Effect of Antihypertensives in a Rodent Model of DOCA-Salt Induced Hypertension" @default.
- W2117702958 cites W1762073497 @default.
- W2117702958 cites W1780627874 @default.
- W2117702958 cites W1966616313 @default.
- W2117702958 cites W1969064534 @default.
- W2117702958 cites W1974114127 @default.
- W2117702958 cites W1974673820 @default.
- W2117702958 cites W1976828693 @default.
- W2117702958 cites W1980835308 @default.
- W2117702958 cites W1983017385 @default.
- W2117702958 cites W1996044010 @default.
- W2117702958 cites W1998933608 @default.
- W2117702958 cites W2000252678 @default.
- W2117702958 cites W2001805133 @default.
- W2117702958 cites W2003295462 @default.
- W2117702958 cites W2003374359 @default.
- W2117702958 cites W2018035901 @default.
- W2117702958 cites W2018715887 @default.
- W2117702958 cites W2028892755 @default.
- W2117702958 cites W2030277350 @default.
- W2117702958 cites W2032194054 @default.
- W2117702958 cites W2036428336 @default.
- W2117702958 cites W2059469256 @default.
- W2117702958 cites W2060514620 @default.
- W2117702958 cites W2065836456 @default.
- W2117702958 cites W2066420869 @default.
- W2117702958 cites W2068128792 @default.
- W2117702958 cites W2069129483 @default.
- W2117702958 cites W2070530568 @default.
- W2117702958 cites W2071150276 @default.
- W2117702958 cites W2077359604 @default.
- W2117702958 cites W2082499830 @default.
- W2117702958 cites W2084347081 @default.
- W2117702958 cites W2088179332 @default.
- W2117702958 cites W2089500756 @default.
- W2117702958 cites W2090752797 @default.
- W2117702958 cites W2092198499 @default.
- W2117702958 cites W2093048739 @default.
- W2117702958 cites W2093157068 @default.
- W2117702958 cites W2101652320 @default.
- W2117702958 cites W2108840350 @default.
- W2117702958 cites W2109591901 @default.
- W2117702958 cites W2113493370 @default.
- W2117702958 cites W2114749347 @default.
- W2117702958 cites W2115785303 @default.
- W2117702958 cites W2120251900 @default.
- W2117702958 cites W2123175521 @default.
- W2117702958 cites W2123295634 @default.
- W2117702958 cites W2128104176 @default.
- W2117702958 cites W2131521192 @default.
- W2117702958 cites W2139130302 @default.
- W2117702958 cites W2144398034 @default.
- W2117702958 cites W2144506241 @default.
- W2117702958 cites W2146625461 @default.
- W2117702958 cites W2156443810 @default.
- W2117702958 cites W2157057477 @default.
- W2117702958 cites W2163137146 @default.
- W2117702958 cites W2321470395 @default.
- W2117702958 cites W2330209657 @default.
- W2117702958 cites W2330238464 @default.
- W2117702958 cites W2330821664 @default.
- W2117702958 cites W4238832237 @default.
- W2117702958 doi "https://doi.org/10.3109/10641963.2013.776567" @default.
- W2117702958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23489008" @default.
- W2117702958 hasPublicationYear "2013" @default.
- W2117702958 type Work @default.
- W2117702958 sameAs 2117702958 @default.
- W2117702958 citedByCount "4" @default.
- W2117702958 countsByYear W21177029582014 @default.
- W2117702958 countsByYear W21177029582015 @default.
- W2117702958 countsByYear W21177029582018 @default.
- W2117702958 countsByYear W21177029582021 @default.
- W2117702958 crossrefType "journal-article" @default.
- W2117702958 hasAuthorship W2117702958A5019131029 @default.
- W2117702958 hasAuthorship W2117702958A5029193472 @default.
- W2117702958 hasAuthorship W2117702958A5080016287 @default.
- W2117702958 hasAuthorship W2117702958A5080942991 @default.
- W2117702958 hasConcept C123915805 @default.
- W2117702958 hasConcept C126322002 @default.
- W2117702958 hasConcept C134018914 @default.
- W2117702958 hasConcept C181199279 @default.
- W2117702958 hasConcept C185592680 @default.
- W2117702958 hasConcept C189135053 @default.
- W2117702958 hasConcept C198710026 @default.
- W2117702958 hasConcept C27016395 @default.
- W2117702958 hasConcept C2776214540 @default.
- W2117702958 hasConcept C2776525901 @default.
- W2117702958 hasConcept C2778525890 @default.
- W2117702958 hasConcept C2779611605 @default.
- W2117702958 hasConcept C2779689624 @default.