FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117746504> ?p ?o ?g. }

• W2117746504 endingPage "1152" @default.
• W2117746504 startingPage "1146" @default.
• W2117746504 abstract "Thymic stromal lymphopoietin (TSLP) is a novel cytokine that triggers the dendritic cell-mediated T(H)2 response and regulatory T cell expansion. The aim of this study is to evaluate whether TSLP and TSLP receptor (TSLPR) are expressed in primary human extravillous trophoblast (EVT), how proimflammatory cytokines (tumor necrosis factor (TNF)-alpha, IL-1beta), T(H)2 and T(H)3 cytokines (IL-4, TGF-beta) and pregnancy-associated hormones regulate TSLP production by EVT and whether the SLP-TSLPR interaction affects the biological behavior of trophoblsts.We assessed TSLP mRNA and protein expression by real-time RT-PCR, ELISA and immunochemistry, respectively. We further investigated effects of TSLP on the proliferation and invasion of trophoblast cells in vitro.The primary EVTs constitutively expressed TSLP and TSLPR. IL-4 and TNF-alpha or pregnancy-associated hormones result in a significant increase in TSLP mRNA expression and protein release from EVT, and TSLP promotes primary EVT proliferation and invasion in vitro.This study has demonstrated that the first-trimester human trophoblast cells express TSLP and TSLPR, that cytokine milieu which mimics the maternal-fetal interface modulates expression of TSLP in trophoblast and that TSLP stimulates trophoblast proliferation and invasion. This suggests that TSLP plays an important role in human EVT invasion and placentation in human early pregnancy." @default.
• W2117746504 created "2016-06-24" @default.
• W2117746504 creator A5001977967 @default.
• W2117746504 creator A5006230341 @default.
• W2117746504 creator A5019377130 @default.
• W2117746504 creator A5031433768 @default.
• W2117746504 creator A5060415586 @default.
• W2117746504 date "2010-03-13" @default.
• W2117746504 modified "2023-09-27" @default.
• W2117746504 title "Functional regulation of thymic stromal lymphopoietin on proliferation and invasion of trophoblasts in human first-trimester pregnancy" @default.
• W2117746504 cites W1570212613 @default.
• W2117746504 cites W1822726093 @default.
• W2117746504 cites W1975438745 @default.
• W2117746504 cites W1979026253 @default.
• W2117746504 cites W2046318425 @default.
• W2117746504 cites W2067919290 @default.
• W2117746504 cites W2089752733 @default.
• W2117746504 cites W2091886117 @default.
• W2117746504 cites W2098386576 @default.
• W2117746504 cites W2109909774 @default.
• W2117746504 cites W2111097663 @default.
• W2117746504 cites W2113465151 @default.
• W2117746504 cites W2136810169 @default.
• W2117746504 cites W2137465231 @default.
• W2117746504 cites W2142233952 @default.
• W2117746504 cites W2146473386 @default.
• W2117746504 cites W2160762126 @default.
• W2117746504 cites W2168026517 @default.
• W2117746504 cites W2170948066 @default.
• W2117746504 cites W4256214420 @default.
• W2117746504 doi "https://doi.org/10.1093/humrep/deq051" @default.
• W2117746504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20228393" @default.
• W2117746504 hasPublicationYear "2010" @default.
• W2117746504 type Work @default.
• W2117746504 sameAs 2117746504 @default.
• W2117746504 citedByCount "24" @default.
• W2117746504 countsByYear W21177465042012 @default.
• W2117746504 countsByYear W21177465042013 @default.
• W2117746504 countsByYear W21177465042014 @default.
• W2117746504 countsByYear W21177465042015 @default.
• W2117746504 countsByYear W21177465042016 @default.
• W2117746504 countsByYear W21177465042021 @default.
• W2117746504 countsByYear W21177465042022 @default.
• W2117746504 crossrefType "journal-article" @default.
• W2117746504 hasAuthorship W2117746504A5001977967 @default.
• W2117746504 hasAuthorship W2117746504A5006230341 @default.
• W2117746504 hasAuthorship W2117746504A5019377130 @default.
• W2117746504 hasAuthorship W2117746504A5031433768 @default.
• W2117746504 hasAuthorship W2117746504A5060415586 @default.
• W2117746504 hasBestOaLocation W21177465041 @default.
• W2117746504 hasConcept C16685009 @default.
• W2117746504 hasConcept C16930146 @default.
• W2117746504 hasConcept C172680121 @default.
• W2117746504 hasConcept C17991360 @default.
• W2117746504 hasConcept C203014093 @default.
• W2117746504 hasConcept C2776953305 @default.
• W2117746504 hasConcept C2777495146 @default.
• W2117746504 hasConcept C2778070265 @default.
• W2117746504 hasConcept C2778690821 @default.
• W2117746504 hasConcept C2779234561 @default.
• W2117746504 hasConcept C45167389 @default.
• W2117746504 hasConcept C502942594 @default.
• W2117746504 hasConcept C54355233 @default.
• W2117746504 hasConcept C71924100 @default.
• W2117746504 hasConcept C86803240 @default.
• W2117746504 hasConcept C95444343 @default.
• W2117746504 hasConceptScore W2117746504C16685009 @default.
• W2117746504 hasConceptScore W2117746504C16930146 @default.
• W2117746504 hasConceptScore W2117746504C172680121 @default.
• W2117746504 hasConceptScore W2117746504C17991360 @default.
• W2117746504 hasConceptScore W2117746504C203014093 @default.
• W2117746504 hasConceptScore W2117746504C2776953305 @default.
• W2117746504 hasConceptScore W2117746504C2777495146 @default.
• W2117746504 hasConceptScore W2117746504C2778070265 @default.
• W2117746504 hasConceptScore W2117746504C2778690821 @default.
• W2117746504 hasConceptScore W2117746504C2779234561 @default.
• W2117746504 hasConceptScore W2117746504C45167389 @default.
• W2117746504 hasConceptScore W2117746504C502942594 @default.
• W2117746504 hasConceptScore W2117746504C54355233 @default.
• W2117746504 hasConceptScore W2117746504C71924100 @default.
• W2117746504 hasConceptScore W2117746504C86803240 @default.
• W2117746504 hasConceptScore W2117746504C95444343 @default.
• W2117746504 hasIssue "5" @default.
• W2117746504 hasLocation W21177465041 @default.
• W2117746504 hasLocation W21177465042 @default.
• W2117746504 hasOpenAccess W2117746504 @default.
• W2117746504 hasPrimaryLocation W21177465041 @default.
• W2117746504 hasRelatedWork W2038011147 @default.
• W2117746504 hasRelatedWork W2042642675 @default.
• W2117746504 hasRelatedWork W2069935301 @default.
• W2117746504 hasRelatedWork W2077917566 @default.
• W2117746504 hasRelatedWork W2117746504 @default.
• W2117746504 hasRelatedWork W2120131335 @default.
• W2117746504 hasRelatedWork W2151034375 @default.
• W2117746504 hasRelatedWork W2398878426 @default.
• W2117746504 hasRelatedWork W2488939801 @default.
• W2117746504 hasRelatedWork W2991178971 @default.
• W2117746504 hasVolume "25" @default.

• next