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- W2117770051 abstract "The main ionotropic receptors (GABAA, NMDA and AMPA) display a sequential participation in neuronal excitation in the neonatal hippocampus. GABA, the principal inhibitory transmitter in the adult CNS, acts as an excitatory transmitter in early postnatal stage. Glutamatergic synaptic transmission is first purely NMDA-receptor based and lacks functional AMPA receptors. Therefore, initially glutamatergic synapses are 'silent' at resting membrane potential, NMDA channels being blocked by Mg2+. However, when GABA and glutamatergic synapses are coactivated during the physiological patterns of activity, GABAA receptors can facilitate the activation of NMDA receptors, playing the role conferred to AMPA receptors later on in development. Determining the mechanisms underlying the development of this 'ménage à trois' will shed light not only on the wide range of trophic roles of glutamate and GABA in the developing brain, but also on the significance of the transition from neonatal to adult forms of plasticity." @default.
- W2117770051 created "2016-06-24" @default.
- W2117770051 creator A5001980807 @default.
- W2117770051 date "1997-11-01" @default.
- W2117770051 modified "2023-09-30" @default.
- W2117770051 title "GABAA, NMDA and AMPA receptors: a developmentally regulated 'ménage à trois'" @default.
- W2117770051 cites W110129881 @default.
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- W2117770051 cites W1484279823 @default.
- W2117770051 cites W1537179351 @default.
- W2117770051 cites W1563576581 @default.
- W2117770051 cites W1589807970 @default.
- W2117770051 cites W1671227548 @default.
- W2117770051 cites W1856380311 @default.
- W2117770051 cites W1955575446 @default.
- W2117770051 cites W1963895777 @default.
- W2117770051 cites W1964418945 @default.
- W2117770051 cites W1967475203 @default.
- W2117770051 cites W1971931358 @default.
- W2117770051 cites W1972829230 @default.
- W2117770051 cites W1976416612 @default.
- W2117770051 cites W1983628676 @default.
- W2117770051 cites W1984994314 @default.
- W2117770051 cites W1986240433 @default.
- W2117770051 cites W1990712757 @default.
- W2117770051 cites W1991905988 @default.
- W2117770051 cites W1992665201 @default.
- W2117770051 cites W1992735831 @default.
- W2117770051 cites W1992792117 @default.
- W2117770051 cites W1998305119 @default.
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- W2117770051 cites W2017213222 @default.
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- W2117770051 cites W2025388015 @default.
- W2117770051 cites W2026708081 @default.
- W2117770051 cites W2030014404 @default.
- W2117770051 cites W2031130044 @default.
- W2117770051 cites W2034137241 @default.
- W2117770051 cites W2035289053 @default.
- W2117770051 cites W2035803576 @default.
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- W2117770051 cites W2106452927 @default.
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- W2117770051 doi "https://doi.org/10.1016/s0166-2236(97)01147-8" @default.
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