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• W2117820862 abstract "The development of proteomic and metabolomic technologies holds the promise to significantly impact patient management by improving diagnosis, unraveling more appropriate therapeutic targets, and enabling more precise prognosis of disease development. Proteomics and metabolomics have been applied with the aim of improving dialysis, defining uremic toxins, and unraveling their origin. Ideally, these technologies should inform us which proteomic or metabolomic compounds are subject to significant alterations of concentration or structure as a result of failing kidney function, and thus can be considered as potential uremic toxins. After a few years of applying these technologies in the area of uremic toxicity studies we are now in a position where we can estimate how and what they can contribute to the field. In this review we critically examine the current literature on the application of proteomics and metabolomics in the context of dialysis and uremic toxins. We highlight the most promising findings, indicate where we see the current need, and which future developments consequently are to be expected, given the technological constraints that undoubtedly exist. The development of proteomic and metabolomic technologies holds the promise to significantly impact patient management by improving diagnosis, unraveling more appropriate therapeutic targets, and enabling more precise prognosis of disease development. Proteomics and metabolomics have been applied with the aim of improving dialysis, defining uremic toxins, and unraveling their origin. Ideally, these technologies should inform us which proteomic or metabolomic compounds are subject to significant alterations of concentration or structure as a result of failing kidney function, and thus can be considered as potential uremic toxins. After a few years of applying these technologies in the area of uremic toxicity studies we are now in a position where we can estimate how and what they can contribute to the field. In this review we critically examine the current literature on the application of proteomics and metabolomics in the context of dialysis and uremic toxins. We highlight the most promising findings, indicate where we see the current need, and which future developments consequently are to be expected, given the technological constraints that undoubtedly exist." @default.
• W2117820862 created "2016-06-24" @default.
• W2117820862 creator A5042966344 @default.
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• W2117820862 creator A5061627231 @default.
• W2117820862 date "2014-03-01" @default.
• W2117820862 modified "2023-09-26" @default.
• W2117820862 title "Proteomics and Metabolomics as Tools to Unravel Novel Culprits and Mechanisms of Uremic Toxicity: Instrument or Hype?" @default.
• W2117820862 cites W1482354611 @default.
• W2117820862 cites W1967321148 @default.
• W2117820862 cites W1968460061 @default.
• W2117820862 cites W1971606140 @default.
• W2117820862 cites W1973529232 @default.
• W2117820862 cites W1973577355 @default.
• W2117820862 cites W1974398249 @default.
• W2117820862 cites W1975579196 @default.
• W2117820862 cites W1980783900 @default.
• W2117820862 cites W1984359045 @default.
• W2117820862 cites W1986562177 @default.
• W2117820862 cites W1987012335 @default.
• W2117820862 cites W1987992135 @default.
• W2117820862 cites W1994397833 @default.
• W2117820862 cites W1994773119 @default.
• W2117820862 cites W1996031455 @default.
• W2117820862 cites W1997847649 @default.
• W2117820862 cites W2002396315 @default.
• W2117820862 cites W2003524197 @default.
• W2117820862 cites W2004799239 @default.
• W2117820862 cites W2006141598 @default.
• W2117820862 cites W2006786034 @default.
• W2117820862 cites W2014372468 @default.
• W2117820862 cites W2019290952 @default.
• W2117820862 cites W2023535481 @default.
• W2117820862 cites W2025623225 @default.
• W2117820862 cites W2027554308 @default.
• W2117820862 cites W2028176752 @default.
• W2117820862 cites W2036601168 @default.
• W2117820862 cites W2042418561 @default.
• W2117820862 cites W2043332056 @default.
• W2117820862 cites W2043903304 @default.
• W2117820862 cites W2056903366 @default.
• W2117820862 cites W2057824539 @default.
• W2117820862 cites W2063957132 @default.
• W2117820862 cites W2066440553 @default.
• W2117820862 cites W2068655235 @default.
• W2117820862 cites W2069436214 @default.
• W2117820862 cites W2071095150 @default.
• W2117820862 cites W2071534982 @default.
• W2117820862 cites W2075373098 @default.
• W2117820862 cites W2078075875 @default.
• W2117820862 cites W2079083489 @default.
• W2117820862 cites W2081266083 @default.
• W2117820862 cites W2084020015 @default.
• W2117820862 cites W2092274825 @default.
• W2117820862 cites W2095884885 @default.
• W2117820862 cites W2096606258 @default.
• W2117820862 cites W2097422761 @default.
• W2117820862 cites W2099000521 @default.
• W2117820862 cites W2104854233 @default.
• W2117820862 cites W2105130711 @default.
• W2117820862 cites W2107363389 @default.
• W2117820862 cites W2108070450 @default.
• W2117820862 cites W2113297279 @default.
• W2117820862 cites W2115498556 @default.
• W2117820862 cites W2116977954 @default.
• W2117820862 cites W2117925356 @default.
• W2117820862 cites W2121509432 @default.
• W2117820862 cites W2122259188 @default.
• W2117820862 cites W2122460910 @default.
• W2117820862 cites W2122825204 @default.
• W2117820862 cites W2123047997 @default.
• W2117820862 cites W2124861786 @default.
• W2117820862 cites W2125770956 @default.
• W2117820862 cites W2133850955 @default.
• W2117820862 cites W2137274797 @default.
• W2117820862 cites W2140351394 @default.
• W2117820862 cites W2143113016 @default.
• W2117820862 cites W2143616363 @default.
• W2117820862 cites W2145073188 @default.
• W2117820862 cites W2146840017 @default.
• W2117820862 cites W2158047247 @default.
• W2117820862 cites W2159759437 @default.
• W2117820862 cites W2166711199 @default.
• W2117820862 cites W2168518104 @default.
• W2117820862 cites W2171201400 @default.
• W2117820862 cites W2398299273 @default.
• W2117820862 cites W9675476 @default.
• W2117820862 doi "https://doi.org/10.1016/j.semnephrol.2014.02.009" @default.
• W2117820862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24780472" @default.
• W2117820862 hasPublicationYear "2014" @default.
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