FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117880227> ?p ?o ?g. }

• W2117880227 endingPage "1972" @default.
• W2117880227 startingPage "1962" @default.
• W2117880227 abstract "Acoustic sensors that exploit resonating quartz crystals directly detect the binding of an analyte to a receptor. Applications include detection of bacteria, viruses, and oligonucleotides and measurement of myoglobin, interleukin 1beta (IL-1beta), and enzyme cofactors.Resonant Acoustic Profiling was combined with a microfluidic lateral flow device incorporating an internal reference control, stable linker chemistry, and immobilized receptors on a disposable sensor chip. Analyte concentrations were determined by analyzing the rate of binding of the analyte to an appropriate receptor.The specificity and affinity of antibody-antigen and enzyme-cofactor interactions were determined without labeling of the receptor or the analyte. We measured protein concentrations (recombinant human IL-1beta and recombinant human myoglobin) and quantified binding of cofactors (NADP+ and NAD+) to the enzyme glucose dehydrogenase. Lower limits of detection were approximately 1 nmol/L (17 ng/mL) for both IL-1beta and human myoglobin. The equilibrium binding constant for NADP+ binding to glucose dehydrogenase was 2.8 mmol/L.Resonant Acoustic Profiling detects analytes in a relatively simple receptor-binding assay in <10 min. Potential applications include real-time immunoassays and biomarker detection. Combination of this technology platform with existing technologies for concentration and presentation of analytes may lead to simple, label-free, high-sensitivity methodologies for reagent and assay validation in clinical chemistry and, ultimately, for real-time in vitro diagnostics." @default.
• W2117880227 created "2016-06-24" @default.
• W2117880227 creator A5005928579 @default.
• W2117880227 creator A5027318408 @default.
• W2117880227 creator A5029384042 @default.
• W2117880227 creator A5031678632 @default.
• W2117880227 creator A5037212734 @default.
• W2117880227 creator A5055623764 @default.
• W2117880227 creator A5064210891 @default.
• W2117880227 creator A5067806181 @default.
• W2117880227 creator A5074910442 @default.
• W2117880227 creator A5086060801 @default.
• W2117880227 date "2005-10-01" @default.
• W2117880227 modified "2023-10-14" @default.
• W2117880227 title "Direct Quantification of Analyte Concentration by Resonant Acoustic Profiling" @default.
• W2117880227 cites W1524884189 @default.
• W2117880227 cites W1594214770 @default.
• W2117880227 cites W1968297070 @default.
• W2117880227 cites W1968613479 @default.
• W2117880227 cites W1969702506 @default.
• W2117880227 cites W1972017339 @default.
• W2117880227 cites W1976040806 @default.
• W2117880227 cites W1990539327 @default.
• W2117880227 cites W1992430761 @default.
• W2117880227 cites W1992612528 @default.
• W2117880227 cites W1994917917 @default.
• W2117880227 cites W1998226299 @default.
• W2117880227 cites W2006254525 @default.
• W2117880227 cites W2009692435 @default.
• W2117880227 cites W2015115704 @default.
• W2117880227 cites W2016833439 @default.
• W2117880227 cites W2019996137 @default.
• W2117880227 cites W2020536991 @default.
• W2117880227 cites W2020664256 @default.
• W2117880227 cites W2021869084 @default.
• W2117880227 cites W2024270686 @default.
• W2117880227 cites W2027129281 @default.
• W2117880227 cites W2028668586 @default.
• W2117880227 cites W2034040908 @default.
• W2117880227 cites W2042537980 @default.
• W2117880227 cites W2043026524 @default.
• W2117880227 cites W2044735980 @default.
• W2117880227 cites W2044973375 @default.
• W2117880227 cites W2047917567 @default.
• W2117880227 cites W2051584037 @default.
• W2117880227 cites W2054197076 @default.
• W2117880227 cites W2055439074 @default.
• W2117880227 cites W2055880637 @default.
• W2117880227 cites W2065593582 @default.
• W2117880227 cites W2067239407 @default.
• W2117880227 cites W2069927159 @default.
• W2117880227 cites W2072962010 @default.
• W2117880227 cites W2073576933 @default.
• W2117880227 cites W2075564560 @default.
• W2117880227 cites W2084028151 @default.
• W2117880227 cites W2090961436 @default.
• W2117880227 cites W2091611185 @default.
• W2117880227 cites W2092430526 @default.
• W2117880227 cites W2098382331 @default.
• W2117880227 cites W2112414534 @default.
• W2117880227 cites W2118725903 @default.
• W2117880227 cites W2119047282 @default.
• W2117880227 cites W2126572275 @default.
• W2117880227 cites W2128113908 @default.
• W2117880227 cites W2134207683 @default.
• W2117880227 cites W2137232736 @default.
• W2117880227 cites W2138248527 @default.
• W2117880227 cites W2149085554 @default.
• W2117880227 cites W2158560940 @default.
• W2117880227 cites W2178054941 @default.
• W2117880227 cites W2201334724 @default.
• W2117880227 cites W2328102298 @default.
• W2117880227 cites W2335132007 @default.
• W2117880227 cites W2599199563 @default.
• W2117880227 doi "https://doi.org/10.1373/clinchem.2005.053249" @default.
• W2117880227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16081504" @default.
• W2117880227 hasPublicationYear "2005" @default.
• W2117880227 type Work @default.
• W2117880227 sameAs 2117880227 @default.
• W2117880227 citedByCount "51" @default.
• W2117880227 countsByYear W21178802272012 @default.
• W2117880227 countsByYear W21178802272013 @default.
• W2117880227 countsByYear W21178802272015 @default.
• W2117880227 countsByYear W21178802272016 @default.
• W2117880227 countsByYear W21178802272017 @default.
• W2117880227 countsByYear W21178802272018 @default.
• W2117880227 countsByYear W21178802272022 @default.
• W2117880227 crossrefType "journal-article" @default.
• W2117880227 hasAuthorship W2117880227A5005928579 @default.
• W2117880227 hasAuthorship W2117880227A5027318408 @default.
• W2117880227 hasAuthorship W2117880227A5029384042 @default.
• W2117880227 hasAuthorship W2117880227A5031678632 @default.
• W2117880227 hasAuthorship W2117880227A5037212734 @default.
• W2117880227 hasAuthorship W2117880227A5055623764 @default.
• W2117880227 hasAuthorship W2117880227A5064210891 @default.
• W2117880227 hasAuthorship W2117880227A5067806181 @default.
• W2117880227 hasAuthorship W2117880227A5074910442 @default.
• W2117880227 hasAuthorship W2117880227A5086060801 @default.

• next