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- W2117883524 endingPage "293" @default.
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- W2117883524 abstract "An exquisite interplay of developmental cues, transcription factors, and coregulatory and signaling proteins support formation of skeletal elements of the jaw during embryogenesis and dynamic remodeling of alveolar bone in postnatal life. These molecules promote initial condensation of the mesenchyme, commitment of the mesenchymal progenitor to osteogenic lineage cells, and differentiation of committed osteoblasts to mature osteocytes within mineralized bone. Parallel regulatory networks promote formation of the functional osteoclast from mononuclear cells to support continuous bone remodeling within the alveolar bone. With an ever expanding list of new regulatory factors, the complexities of the molecular mechanisms that control gene expression in skeletal cells are being further appreciated. This article examines the multifunctional roles of prominent nuclear proteins, cytokines, hormones, and paracrine factors that control osteogenesis." @default.
- W2117883524 created "2016-06-24" @default.
- W2117883524 creator A5031313195 @default.
- W2117883524 creator A5063850442 @default.
- W2117883524 creator A5078034342 @default.
- W2117883524 date "2010-08-01" @default.
- W2117883524 modified "2023-10-13" @default.
- W2117883524 title "Genetic and Transcriptional Control of Bone Formation" @default.
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- W2117883524 doi "https://doi.org/10.1016/j.coms.2010.05.001" @default.
- W2117883524 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2923651" @default.
- W2117883524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20713262" @default.
- W2117883524 hasPublicationYear "2010" @default.
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