Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117907904> ?p ?o ?g. }
- W2117907904 endingPage "2129" @default.
- W2117907904 startingPage "2129" @default.
- W2117907904 abstract "We present a graphene oxide (GO) integrated disposable electrochemical sensor for the enhanced detection of nucleic acids and the sensitive monitoring of the surface-confined interactions between the anticancer drug mitomycin C (MC) and DNA. Interfacial interactions between immobilized calf thymus double-stranded (dsDNA) and anticancer drug MC were investigated using differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) techniques. Based on three repetitive voltammetric measurements of 120 μg mL−1 DNA immobilized on GO-modified electrodes, the RSD % (n = 3) was calculated as 10.47% and the detection limit (DL) for dsDNA was found to be 9.06 μg mL−1. EIS studies revealed that the binding of the drug MC to dsDNA leads to a gradual decrease of its negative charge. As a consequence of this interaction, the negative redox species were allowed to approach the electrode, and thus increase the charge transfer kinetics. On the other hand, DPV studies exploited the decrease of the guanine signal due to drug binding as the basis for specifically probing the biointeraction process between MC and dsDNA." @default.
- W2117907904 created "2016-06-24" @default.
- W2117907904 creator A5009906839 @default.
- W2117907904 creator A5025045822 @default.
- W2117907904 creator A5032916618 @default.
- W2117907904 creator A5045150413 @default.
- W2117907904 creator A5053286687 @default.
- W2117907904 creator A5055763793 @default.
- W2117907904 creator A5064837487 @default.
- W2117907904 date "2012-01-01" @default.
- W2117907904 modified "2023-10-15" @default.
- W2117907904 title "Graphene oxide integrated sensor for electrochemical monitoring of mitomycin C–DNA interaction" @default.
- W2117907904 cites W1773832525 @default.
- W2117907904 cites W1916948239 @default.
- W2117907904 cites W1966300235 @default.
- W2117907904 cites W1971186261 @default.
- W2117907904 cites W1976081241 @default.
- W2117907904 cites W1982857557 @default.
- W2117907904 cites W1982904490 @default.
- W2117907904 cites W1987550714 @default.
- W2117907904 cites W1987917516 @default.
- W2117907904 cites W1988976176 @default.
- W2117907904 cites W1993413761 @default.
- W2117907904 cites W1996028780 @default.
- W2117907904 cites W1996517624 @default.
- W2117907904 cites W1998693685 @default.
- W2117907904 cites W1999923597 @default.
- W2117907904 cites W2000693658 @default.
- W2117907904 cites W2000834373 @default.
- W2117907904 cites W2009539111 @default.
- W2117907904 cites W2014180683 @default.
- W2117907904 cites W2014935324 @default.
- W2117907904 cites W2018809718 @default.
- W2117907904 cites W2023711677 @default.
- W2117907904 cites W2030198190 @default.
- W2117907904 cites W2031394361 @default.
- W2117907904 cites W2036939480 @default.
- W2117907904 cites W2038401336 @default.
- W2117907904 cites W2041858177 @default.
- W2117907904 cites W2045483092 @default.
- W2117907904 cites W2046858005 @default.
- W2117907904 cites W2050226266 @default.
- W2117907904 cites W2052976411 @default.
- W2117907904 cites W2056523172 @default.
- W2117907904 cites W2057219487 @default.
- W2117907904 cites W2060512241 @default.
- W2117907904 cites W2061982359 @default.
- W2117907904 cites W2070945608 @default.
- W2117907904 cites W2072335788 @default.
- W2117907904 cites W2074502541 @default.
- W2117907904 cites W2087321667 @default.
- W2117907904 cites W2088986321 @default.
- W2117907904 cites W2091666349 @default.
- W2117907904 cites W2093540374 @default.
- W2117907904 cites W2110622269 @default.
- W2117907904 cites W2119373267 @default.
- W2117907904 cites W2157046295 @default.
- W2117907904 cites W2161823114 @default.
- W2117907904 cites W4251751762 @default.
- W2117907904 doi "https://doi.org/10.1039/c2an16011k" @default.
- W2117907904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22439135" @default.
- W2117907904 hasPublicationYear "2012" @default.
- W2117907904 type Work @default.
- W2117907904 sameAs 2117907904 @default.
- W2117907904 citedByCount "71" @default.
- W2117907904 countsByYear W21179079042012 @default.
- W2117907904 countsByYear W21179079042013 @default.
- W2117907904 countsByYear W21179079042014 @default.
- W2117907904 countsByYear W21179079042015 @default.
- W2117907904 countsByYear W21179079042016 @default.
- W2117907904 countsByYear W21179079042017 @default.
- W2117907904 countsByYear W21179079042018 @default.
- W2117907904 countsByYear W21179079042019 @default.
- W2117907904 countsByYear W21179079042020 @default.
- W2117907904 countsByYear W21179079042021 @default.
- W2117907904 countsByYear W21179079042022 @default.
- W2117907904 countsByYear W21179079042023 @default.
- W2117907904 crossrefType "journal-article" @default.
- W2117907904 hasAuthorship W2117907904A5009906839 @default.
- W2117907904 hasAuthorship W2117907904A5025045822 @default.
- W2117907904 hasAuthorship W2117907904A5032916618 @default.
- W2117907904 hasAuthorship W2117907904A5045150413 @default.
- W2117907904 hasAuthorship W2117907904A5053286687 @default.
- W2117907904 hasAuthorship W2117907904A5055763793 @default.
- W2117907904 hasAuthorship W2117907904A5064837487 @default.
- W2117907904 hasBestOaLocation W21179079042 @default.
- W2117907904 hasConcept C104317684 @default.
- W2117907904 hasConcept C113196181 @default.
- W2117907904 hasConcept C119128265 @default.
- W2117907904 hasConcept C141071460 @default.
- W2117907904 hasConcept C147789679 @default.
- W2117907904 hasConcept C171250308 @default.
- W2117907904 hasConcept C17525397 @default.
- W2117907904 hasConcept C178790620 @default.
- W2117907904 hasConcept C179104552 @default.
- W2117907904 hasConcept C185592680 @default.
- W2117907904 hasConcept C188095982 @default.
- W2117907904 hasConcept C192562407 @default.