FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117917103> ?p ?o ?g. }

• W2117917103 endingPage "46" @default.
• W2117917103 startingPage "37" @default.
• W2117917103 abstract "Sulfa-antibiotics (sulfonamides) are widely used in veterinary medicine. Meat and milk from treated animals can be contaminated with sulfa residues. Current sulfonamide assays are unfit for screening of food, because they are either too laborious, insensitive or specific for a few sulfa compounds only. An immunoassay for detection of all sulfas in a single reaction would be useful for screening. Previously we have improved the broad specificity sulfa binding of antibody 27G3 with random mutagenesis and phage display. In order to improve the properties of this antibody further, mutants from the previous study were recombined and more mutations introduced. These new libraries were enriched with phage display and several different mutant antibodies were isolated. The cross-reaction profile of the best mutant was better than that of the wild-type antibody and the mutants of the previous study: it was capable of binding 10 of the tested 13 sulfonamides within a narrow concentration range and also bound the rest of the sulfas 5- to 11-fold better than the mutants of the previous study." @default.
• W2117917103 created "2016-06-24" @default.
• W2117917103 creator A5007556125 @default.
• W2117917103 creator A5019373658 @default.
• W2117917103 creator A5022388298 @default.
• W2117917103 creator A5034469014 @default.
• W2117917103 creator A5082300574 @default.
• W2117917103 creator A5084076358 @default.
• W2117917103 date "2003-01-01" @default.
• W2117917103 modified "2023-10-14" @default.
• W2117917103 title "Further improvement of broad specificity hapten recognition with protein engineering" @default.
• W2117917103 cites W1519011873 @default.
• W2117917103 cites W1965960192 @default.
• W2117917103 cites W1973366536 @default.
• W2117917103 cites W1976044380 @default.
• W2117917103 cites W1977224888 @default.
• W2117917103 cites W1990496227 @default.
• W2117917103 cites W1996192954 @default.
• W2117917103 cites W2012820552 @default.
• W2117917103 cites W2034287217 @default.
• W2117917103 cites W2035914589 @default.
• W2117917103 cites W2047379934 @default.
• W2117917103 cites W2051319705 @default.
• W2117917103 cites W2063417559 @default.
• W2117917103 cites W2064541635 @default.
• W2117917103 cites W2071086763 @default.
• W2117917103 cites W2075465451 @default.
• W2117917103 cites W2077566364 @default.
• W2117917103 cites W2083177539 @default.
• W2117917103 cites W2087393272 @default.
• W2117917103 cites W2092894270 @default.
• W2117917103 cites W2114446676 @default.
• W2117917103 cites W2136188860 @default.
• W2117917103 cites W2140677913 @default.
• W2117917103 cites W2161020397 @default.
• W2117917103 cites W2168729887 @default.
• W2117917103 cites W2328340343 @default.
• W2117917103 doi "https://doi.org/10.1093/proeng/gzg010" @default.
• W2117917103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12646691" @default.
• W2117917103 hasPublicationYear "2003" @default.
• W2117917103 type Work @default.
• W2117917103 sameAs 2117917103 @default.
• W2117917103 citedByCount "43" @default.
• W2117917103 countsByYear W21179171032012 @default.
• W2117917103 countsByYear W21179171032013 @default.
• W2117917103 countsByYear W21179171032014 @default.
• W2117917103 countsByYear W21179171032015 @default.
• W2117917103 countsByYear W21179171032016 @default.
• W2117917103 countsByYear W21179171032017 @default.
• W2117917103 countsByYear W21179171032018 @default.
• W2117917103 countsByYear W21179171032022 @default.
• W2117917103 crossrefType "journal-article" @default.
• W2117917103 hasAuthorship W2117917103A5007556125 @default.
• W2117917103 hasAuthorship W2117917103A5019373658 @default.
• W2117917103 hasAuthorship W2117917103A5022388298 @default.
• W2117917103 hasAuthorship W2117917103A5034469014 @default.
• W2117917103 hasAuthorship W2117917103A5082300574 @default.
• W2117917103 hasAuthorship W2117917103A5084076358 @default.
• W2117917103 hasBestOaLocation W21179171031 @default.
• W2117917103 hasConcept C104317684 @default.
• W2117917103 hasConcept C143065580 @default.
• W2117917103 hasConcept C147816474 @default.
• W2117917103 hasConcept C153911025 @default.
• W2117917103 hasConcept C159654299 @default.
• W2117917103 hasConcept C16318435 @default.
• W2117917103 hasConcept C181199279 @default.
• W2117917103 hasConcept C185592680 @default.
• W2117917103 hasConcept C186268636 @default.
• W2117917103 hasConcept C2780420688 @default.
• W2117917103 hasConcept C2781039511 @default.
• W2117917103 hasConcept C29144244 @default.
• W2117917103 hasConcept C54355233 @default.
• W2117917103 hasConcept C55493867 @default.
• W2117917103 hasConcept C71240020 @default.
• W2117917103 hasConcept C86803240 @default.
• W2117917103 hasConceptScore W2117917103C104317684 @default.
• W2117917103 hasConceptScore W2117917103C143065580 @default.
• W2117917103 hasConceptScore W2117917103C147816474 @default.
• W2117917103 hasConceptScore W2117917103C153911025 @default.
• W2117917103 hasConceptScore W2117917103C159654299 @default.
• W2117917103 hasConceptScore W2117917103C16318435 @default.
• W2117917103 hasConceptScore W2117917103C181199279 @default.
• W2117917103 hasConceptScore W2117917103C185592680 @default.
• W2117917103 hasConceptScore W2117917103C186268636 @default.
• W2117917103 hasConceptScore W2117917103C2780420688 @default.
• W2117917103 hasConceptScore W2117917103C2781039511 @default.
• W2117917103 hasConceptScore W2117917103C29144244 @default.
• W2117917103 hasConceptScore W2117917103C54355233 @default.
• W2117917103 hasConceptScore W2117917103C55493867 @default.
• W2117917103 hasConceptScore W2117917103C71240020 @default.
• W2117917103 hasConceptScore W2117917103C86803240 @default.
• W2117917103 hasIssue "1" @default.
• W2117917103 hasLocation W21179171031 @default.
• W2117917103 hasLocation W21179171032 @default.
• W2117917103 hasOpenAccess W2117917103 @default.
• W2117917103 hasPrimaryLocation W21179171031 @default.
• W2117917103 hasRelatedWork W1517487682 @default.
• W2117917103 hasRelatedWork W1976832055 @default.

• next