Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117939876> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2117939876 endingPage "678" @default.
- W2117939876 startingPage "672" @default.
- W2117939876 abstract "Lung cancer and tuberculosis cause significant morbidity and mortality worldwide. Tuberculosis may increase lung cancer risk through substantial and prolonged pulmonary inflammation. However, prospective data on tuberculosis and lung cancer risk are limited.Our study included 29,133 Finnish male smokers followed prospectively in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (1985-2005). Lung cancers were identified through linkage with the Finnish Cancer Registry, and hospital-treated tuberculosis cases were ascertained from the National Hospital Discharge Register. We assessed the association between tuberculosis and lung cancer risk with proportional hazards regression models, adjusting for age and cigarette smoking.Forty-four lung cancer cases occurred among 273 men with tuberculosis (incidence rate = 1,786 per 100,000 person-years). Tuberculosis was associated with a two-fold elevation in lung cancer risk (HR = 1.97; 95% CI = 1.46-2.65) with significant associations observed for both incident (HR = 2.05; 95% CI = 1.42-2.96) and prevalent tuberculosis (HR = 1.82; 95% CI = 1.09-3.02). Lung cancer risk was greatest in the 2-year window after tuberculosis diagnosis (HR = 5.01; 95% CI = 2.96-8.48) but remained elevated at longer latencies (HR = 1.53; 95% CI = 1.07-2.20). Though tuberculosis was associated with an increased risk of squamous cell carcinoma (HR = 3.71), adenocarcinoma (HR = 1.71), small cell carcinoma (HR = 1.72), and lung cancer of other (HR = 1.23) and unknown histologies (HR = 1.35), only the association for squamous cell carcinoma was statistically significant.Tuberculosis is associated with increased lung cancer risk in male smokers.Our results add to the growing body of evidence implicating chronic inflammation and pulmonary scarring in the etiology of lung cancer." @default.
- W2117939876 created "2016-06-24" @default.
- W2117939876 creator A5027838123 @default.
- W2117939876 creator A5035778053 @default.
- W2117939876 creator A5041592688 @default.
- W2117939876 creator A5068249093 @default.
- W2117939876 date "2011-03-31" @default.
- W2117939876 modified "2023-10-10" @default.
- W2117939876 title "Increased Risk of Lung Cancer in Men with Tuberculosis in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study" @default.
- W2117939876 cites W1525444530 @default.
- W2117939876 cites W1963712255 @default.
- W2117939876 cites W2003453766 @default.
- W2117939876 cites W2009766515 @default.
- W2117939876 cites W2020830322 @default.
- W2117939876 cites W2029555558 @default.
- W2117939876 cites W2038157812 @default.
- W2117939876 cites W2060509240 @default.
- W2117939876 cites W2062888602 @default.
- W2117939876 cites W2069477240 @default.
- W2117939876 cites W2069665972 @default.
- W2117939876 cites W2081286349 @default.
- W2117939876 cites W2140760195 @default.
- W2117939876 cites W2146385699 @default.
- W2117939876 cites W2153772720 @default.
- W2117939876 cites W2155962828 @default.
- W2117939876 cites W2158338067 @default.
- W2117939876 cites W2170346609 @default.
- W2117939876 cites W2188800693 @default.
- W2117939876 cites W4237426518 @default.
- W2117939876 doi "https://doi.org/10.1158/1055-9965.epi-10-1166" @default.
- W2117939876 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3076700" @default.
- W2117939876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21335509" @default.
- W2117939876 hasPublicationYear "2011" @default.
- W2117939876 type Work @default.
- W2117939876 sameAs 2117939876 @default.
- W2117939876 citedByCount "85" @default.
- W2117939876 countsByYear W21179398762012 @default.
- W2117939876 countsByYear W21179398762013 @default.
- W2117939876 countsByYear W21179398762014 @default.
- W2117939876 countsByYear W21179398762015 @default.
- W2117939876 countsByYear W21179398762016 @default.
- W2117939876 countsByYear W21179398762017 @default.
- W2117939876 countsByYear W21179398762018 @default.
- W2117939876 countsByYear W21179398762019 @default.
- W2117939876 countsByYear W21179398762020 @default.
- W2117939876 countsByYear W21179398762021 @default.
- W2117939876 countsByYear W21179398762022 @default.
- W2117939876 countsByYear W21179398762023 @default.
- W2117939876 crossrefType "journal-article" @default.
- W2117939876 hasAuthorship W2117939876A5027838123 @default.
- W2117939876 hasAuthorship W2117939876A5035778053 @default.
- W2117939876 hasAuthorship W2117939876A5041592688 @default.
- W2117939876 hasAuthorship W2117939876A5068249093 @default.
- W2117939876 hasBestOaLocation W21179398761 @default.
- W2117939876 hasConcept C121608353 @default.
- W2117939876 hasConcept C126322002 @default.
- W2117939876 hasConcept C142724271 @default.
- W2117939876 hasConcept C143998085 @default.
- W2117939876 hasConcept C188816634 @default.
- W2117939876 hasConcept C2776256026 @default.
- W2117939876 hasConcept C2778527826 @default.
- W2117939876 hasConcept C2781069245 @default.
- W2117939876 hasConcept C71924100 @default.
- W2117939876 hasConcept C90924648 @default.
- W2117939876 hasConceptScore W2117939876C121608353 @default.
- W2117939876 hasConceptScore W2117939876C126322002 @default.
- W2117939876 hasConceptScore W2117939876C142724271 @default.
- W2117939876 hasConceptScore W2117939876C143998085 @default.
- W2117939876 hasConceptScore W2117939876C188816634 @default.
- W2117939876 hasConceptScore W2117939876C2776256026 @default.
- W2117939876 hasConceptScore W2117939876C2778527826 @default.
- W2117939876 hasConceptScore W2117939876C2781069245 @default.
- W2117939876 hasConceptScore W2117939876C71924100 @default.
- W2117939876 hasConceptScore W2117939876C90924648 @default.
- W2117939876 hasIssue "4" @default.
- W2117939876 hasLocation W21179398761 @default.
- W2117939876 hasLocation W21179398762 @default.
- W2117939876 hasLocation W21179398763 @default.
- W2117939876 hasLocation W21179398764 @default.
- W2117939876 hasOpenAccess W2117939876 @default.
- W2117939876 hasPrimaryLocation W21179398761 @default.
- W2117939876 hasRelatedWork W2160144478 @default.
- W2117939876 hasRelatedWork W2367214875 @default.
- W2117939876 hasRelatedWork W2390152934 @default.
- W2117939876 hasRelatedWork W2442450740 @default.
- W2117939876 hasRelatedWork W2463337194 @default.
- W2117939876 hasRelatedWork W2605235755 @default.
- W2117939876 hasRelatedWork W2650715939 @default.
- W2117939876 hasRelatedWork W2778158817 @default.
- W2117939876 hasRelatedWork W2884171184 @default.
- W2117939876 hasRelatedWork W2908507668 @default.
- W2117939876 hasVolume "20" @default.
- W2117939876 isParatext "false" @default.
- W2117939876 isRetracted "false" @default.
- W2117939876 magId "2117939876" @default.
- W2117939876 workType "article" @default.