Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118047328> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2118047328 endingPage "24" @default.
- W2118047328 startingPage "619" @default.
- W2118047328 abstract "Baby boomers (BB) entering retirement represent a significant burden on medical resources. The unique lifestyle characteristics engendered by the BB may lead to different endometrial cancer characteristics that bear understanding. We sought to characterize BB with endometrioid carcinoma after hysterectomy and compare the results to those of prior to the baby boomers (PB).After reviewing our prospectively maintained database of 1,450 patients with endometrial cancer, we identified 595 patients who underwent hysterectomy for 1988 International Federation of Gynecologic Oncology (FIGO) stage I-II uterine endometrioid carcinomas, who were born between 1926 and 1964. Their medical records were reviewed in this Institutional review board (IRB)-approved study. Patients with non-endometrioid carcinoma and those who received preoperative therapy were excluded. Patients were defined as BB (born 1946-1964) or PB (born in 1926-1945). The two groups were compared regarding patients' demographics, tumor characteristics and survival. Following a univariate analysis, multivariable modeling was carried out using Cox regression analysis.All patients underwent hysterectomy with a minimum of two years' follow-up. There were 234 patients (39%) in the BB group and 361 patients (61%) in the PB group. Median follow-up for the study cohort was 56 months. BB had higher body mass index (p=0.027), lower tumor grade (p=0.002), earlier FIGO stage (p=0.023), higher number of dissected lymph nodes (p=0.008), less lymphvascular space involvement (p=<0.034), less utilization of adjuvant therapy (p=<0.001), and younger age at diagnosis (p=0.002). However, there was no significant difference found between the BB and PB in regards to local control, disease-specific survival and overall survival. For the study cohort, FIGO stage and tumor grade were independent predictors of recurrence-free and disease-specific survival. There was a trend towards shorter overall survival for the PB women (p=0.063).Although tumor characteristics were more favorable in the BB group of women, local control and survival end-points were not statistically different compared to those of the PB group. As more BB are diagnosed with endometrial carcinoma, further research is warranted to further elucidate the characteristic differences in endometrial carcinoma, if any, in this generation." @default.
- W2118047328 created "2016-06-24" @default.
- W2118047328 creator A5032295905 @default.
- W2118047328 creator A5042305745 @default.
- W2118047328 creator A5042690121 @default.
- W2118047328 creator A5051137475 @default.
- W2118047328 creator A5052638703 @default.
- W2118047328 creator A5060410262 @default.
- W2118047328 creator A5067479810 @default.
- W2118047328 date "2013-02-01" @default.
- W2118047328 modified "2023-09-26" @default.
- W2118047328 title "Endometrial carcinoma in the baby boomer generation. Tumor characteristics and clinical outcome." @default.
- W2118047328 cites W1964182344 @default.
- W2118047328 cites W1972685913 @default.
- W2118047328 cites W1984327851 @default.
- W2118047328 cites W2006426441 @default.
- W2118047328 cites W2031924971 @default.
- W2118047328 cites W2057046277 @default.
- W2118047328 cites W2068629674 @default.
- W2118047328 cites W2101076164 @default.
- W2118047328 cites W2103818125 @default.
- W2118047328 cites W2113017183 @default.
- W2118047328 cites W2147101451 @default.
- W2118047328 cites W2153383900 @default.
- W2118047328 cites W2155433338 @default.
- W2118047328 cites W3025735868 @default.
- W2118047328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23393357" @default.
- W2118047328 hasPublicationYear "2013" @default.
- W2118047328 type Work @default.
- W2118047328 sameAs 2118047328 @default.
- W2118047328 citedByCount "1" @default.
- W2118047328 countsByYear W21180473282013 @default.
- W2118047328 crossrefType "journal-article" @default.
- W2118047328 hasAuthorship W2118047328A5032295905 @default.
- W2118047328 hasAuthorship W2118047328A5042305745 @default.
- W2118047328 hasAuthorship W2118047328A5042690121 @default.
- W2118047328 hasAuthorship W2118047328A5051137475 @default.
- W2118047328 hasAuthorship W2118047328A5052638703 @default.
- W2118047328 hasAuthorship W2118047328A5060410262 @default.
- W2118047328 hasAuthorship W2118047328A5067479810 @default.
- W2118047328 hasConcept C121608353 @default.
- W2118047328 hasConcept C126322002 @default.
- W2118047328 hasConcept C141071460 @default.
- W2118047328 hasConcept C143998085 @default.
- W2118047328 hasConcept C144301174 @default.
- W2118047328 hasConcept C146357865 @default.
- W2118047328 hasConcept C151730666 @default.
- W2118047328 hasConcept C2777088508 @default.
- W2118047328 hasConcept C2777546739 @default.
- W2118047328 hasConcept C2777982462 @default.
- W2118047328 hasConcept C2779494336 @default.
- W2118047328 hasConcept C29456083 @default.
- W2118047328 hasConcept C38180746 @default.
- W2118047328 hasConcept C50382708 @default.
- W2118047328 hasConcept C71924100 @default.
- W2118047328 hasConcept C72563966 @default.
- W2118047328 hasConcept C86803240 @default.
- W2118047328 hasConceptScore W2118047328C121608353 @default.
- W2118047328 hasConceptScore W2118047328C126322002 @default.
- W2118047328 hasConceptScore W2118047328C141071460 @default.
- W2118047328 hasConceptScore W2118047328C143998085 @default.
- W2118047328 hasConceptScore W2118047328C144301174 @default.
- W2118047328 hasConceptScore W2118047328C146357865 @default.
- W2118047328 hasConceptScore W2118047328C151730666 @default.
- W2118047328 hasConceptScore W2118047328C2777088508 @default.
- W2118047328 hasConceptScore W2118047328C2777546739 @default.
- W2118047328 hasConceptScore W2118047328C2777982462 @default.
- W2118047328 hasConceptScore W2118047328C2779494336 @default.
- W2118047328 hasConceptScore W2118047328C29456083 @default.
- W2118047328 hasConceptScore W2118047328C38180746 @default.
- W2118047328 hasConceptScore W2118047328C50382708 @default.
- W2118047328 hasConceptScore W2118047328C71924100 @default.
- W2118047328 hasConceptScore W2118047328C72563966 @default.
- W2118047328 hasConceptScore W2118047328C86803240 @default.
- W2118047328 hasIssue "2" @default.
- W2118047328 hasLocation W21180473281 @default.
- W2118047328 hasOpenAccess W2118047328 @default.
- W2118047328 hasPrimaryLocation W21180473281 @default.
- W2118047328 hasRelatedWork W1758517966 @default.
- W2118047328 hasRelatedWork W2094236905 @default.
- W2118047328 hasRelatedWork W2118047328 @default.
- W2118047328 hasRelatedWork W2142606045 @default.
- W2118047328 hasRelatedWork W2734526255 @default.
- W2118047328 hasRelatedWork W2971574507 @default.
- W2118047328 hasRelatedWork W2993070192 @default.
- W2118047328 hasRelatedWork W3200592310 @default.
- W2118047328 hasRelatedWork W4200040154 @default.
- W2118047328 hasRelatedWork W4220702183 @default.
- W2118047328 hasVolume "33" @default.
- W2118047328 isParatext "false" @default.
- W2118047328 isRetracted "false" @default.
- W2118047328 magId "2118047328" @default.
- W2118047328 workType "article" @default.