FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118049614> ?p ?o ?g. }

• W2118049614 endingPage "488" @default.
• W2118049614 startingPage "482" @default.
• W2118049614 abstract "p16 immunostaining has been examined to detect high-grade cervical intraepithelial neoplasia grade (CIN2+) in Pap cytology specimens. However, the utility of p16 in predicting CIN2+ in Pap specimens with atypical squamous cells of undetermined significance (ASC-US) or atypical squamous cells, cannot exclude high-grade squamous intraepithelial neoplasm (ASC-H), is controversial. In this study, we evaluated the utility of p16 immunostaining for predicting CIN2+ in 78 Pap specimens with ASC-US/ASC-H and compared the results in high-risk HPV DNA and the follow-up biopsies. p16 immunostaining was positive in 47% (37/78) of the Pap specimens. Of the 13 Pap specimens with follow-up biopsy results of CIN2+, 7 (54%) were positive for p16. p16 positivity in the Pap specimens was not significantly associated with a CIN2+ biopsy result (P = 0.76). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of p16 immunostaining for predicting CIN2+ were 54%, 52%, 19%, and 85%, respectively. High-risk HPV DNA was detected in 40% (31/78) of the Pap specimens. The sensitivity, specificity, PPV, and NPV of HPV DNA for predicting CIN2+ were 100%, 72%, 42%, and 100%, respectively. High-risk HPV genotypes were detected in six p16-negative specimens with follow-up biopsy results of CIN2+. Our findings suggest that the utility of p16 immunostaining for predicting CIN2+ in Pap specimens with ASC-US/ASC-H is limited. Scant abnormal cells in Pap specimens with ASC-US/ASC-H may have contributed to the low p16 sensitivity. Diagn. Cytopathol., 2011. © 2010 Wiley-Liss, Inc." @default.
• W2118049614 created "2016-06-24" @default.
• W2118049614 creator A5005818396 @default.
• W2118049614 creator A5009021249 @default.
• W2118049614 creator A5032779202 @default.
• W2118049614 creator A5045409917 @default.
• W2118049614 creator A5046003382 @default.
• W2118049614 creator A5060592779 @default.
• W2118049614 creator A5088293773 @default.
• W2118049614 date "2010-07-06" @default.
• W2118049614 modified "2023-09-27" @default.
• W2118049614 title "Evaluation of p16 immunostaining to predict high-grade cervical intraepithelial neoplasia in women with Pap results of atypical squamous cells of undetermined significance" @default.
• W2118049614 cites W1575780694 @default.
• W2118049614 cites W1965734326 @default.
• W2118049614 cites W1971998054 @default.
• W2118049614 cites W1983231924 @default.
• W2118049614 cites W1987072732 @default.
• W2118049614 cites W1988021002 @default.
• W2118049614 cites W1988558796 @default.
• W2118049614 cites W1998218812 @default.
• W2118049614 cites W1999160921 @default.
• W2118049614 cites W2000012702 @default.
• W2118049614 cites W2008106081 @default.
• W2118049614 cites W2014846342 @default.
• W2118049614 cites W2020171800 @default.
• W2118049614 cites W2028750854 @default.
• W2118049614 cites W2033316661 @default.
• W2118049614 cites W2035348064 @default.
• W2118049614 cites W2037082184 @default.
• W2118049614 cites W2038845680 @default.
• W2118049614 cites W2038986660 @default.
• W2118049614 cites W2066834338 @default.
• W2118049614 cites W2070070984 @default.
• W2118049614 cites W2073439462 @default.
• W2118049614 cites W2077139988 @default.
• W2118049614 cites W2077418511 @default.
• W2118049614 cites W2088430806 @default.
• W2118049614 cites W2093339404 @default.
• W2118049614 cites W2115240529 @default.
• W2118049614 cites W2117775808 @default.
• W2118049614 cites W2133765716 @default.
• W2118049614 cites W2155863717 @default.
• W2118049614 cites W2159632074 @default.
• W2118049614 cites W2167450170 @default.
• W2118049614 cites W4237801062 @default.
• W2118049614 doi "https://doi.org/10.1002/dc.21415" @default.
• W2118049614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20607682" @default.
• W2118049614 hasPublicationYear "2010" @default.
• W2118049614 type Work @default.
• W2118049614 sameAs 2118049614 @default.
• W2118049614 citedByCount "14" @default.
• W2118049614 countsByYear W21180496142012 @default.
• W2118049614 countsByYear W21180496142013 @default.
• W2118049614 countsByYear W21180496142014 @default.
• W2118049614 countsByYear W21180496142015 @default.
• W2118049614 countsByYear W21180496142016 @default.
• W2118049614 countsByYear W21180496142017 @default.
• W2118049614 countsByYear W21180496142019 @default.
• W2118049614 countsByYear W21180496142020 @default.
• W2118049614 crossrefType "journal-article" @default.
• W2118049614 hasAuthorship W2118049614A5005818396 @default.
• W2118049614 hasAuthorship W2118049614A5009021249 @default.
• W2118049614 hasAuthorship W2118049614A5032779202 @default.
• W2118049614 hasAuthorship W2118049614A5045409917 @default.
• W2118049614 hasAuthorship W2118049614A5046003382 @default.
• W2118049614 hasAuthorship W2118049614A5060592779 @default.
• W2118049614 hasAuthorship W2118049614A5088293773 @default.
• W2118049614 hasConcept C121608353 @default.
• W2118049614 hasConcept C126322002 @default.
• W2118049614 hasConcept C142724271 @default.
• W2118049614 hasConcept C18823058 @default.
• W2118049614 hasConcept C204232928 @default.
• W2118049614 hasConcept C2775934546 @default.
• W2118049614 hasConcept C2777343196 @default.
• W2118049614 hasConcept C2778220009 @default.
• W2118049614 hasConcept C29456083 @default.
• W2118049614 hasConcept C4224716 @default.
• W2118049614 hasConcept C71924100 @default.
• W2118049614 hasConceptScore W2118049614C121608353 @default.
• W2118049614 hasConceptScore W2118049614C126322002 @default.
• W2118049614 hasConceptScore W2118049614C142724271 @default.
• W2118049614 hasConceptScore W2118049614C18823058 @default.
• W2118049614 hasConceptScore W2118049614C204232928 @default.
• W2118049614 hasConceptScore W2118049614C2775934546 @default.
• W2118049614 hasConceptScore W2118049614C2777343196 @default.
• W2118049614 hasConceptScore W2118049614C2778220009 @default.
• W2118049614 hasConceptScore W2118049614C29456083 @default.
• W2118049614 hasConceptScore W2118049614C4224716 @default.
• W2118049614 hasConceptScore W2118049614C71924100 @default.
• W2118049614 hasIssue "7" @default.
• W2118049614 hasLocation W21180496141 @default.
• W2118049614 hasOpenAccess W2118049614 @default.
• W2118049614 hasPrimaryLocation W21180496141 @default.
• W2118049614 hasRelatedWork W1964517198 @default.
• W2118049614 hasRelatedWork W2022498945 @default.
• W2118049614 hasRelatedWork W202920663 @default.
• W2118049614 hasRelatedWork W2079153990 @default.
• W2118049614 hasRelatedWork W2084136175 @default.

• next