Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118049964> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2118049964 endingPage "189" @default.
- W2118049964 startingPage "185" @default.
- W2118049964 abstract "1. The aim of the present study was to determine the modulatory effects of dipyridamole on purinergic and adrenergic transmission in the canine isolated, perfused splenic artery. 2. Periarterial nerve electrical stimulation readily induced a double-peaked vasoconstriction consisting of an initial transient, predominantly P2X receptor-mediated constriction followed by a prolonged, mainly alpha1-adrenoceptor-mediated response. 3. Exposure of tissues to dipyridamole (0.1-1 micro mol/L) dose-dependently inhibited both the first and second peaks of the vasoconstrictor response at a low frequency of stimulation (1 Hz), whereas at an intermediate frequency of stimulation (4 Hz), the first peak of the response was depressed without any significant effect being observed on the second peak of constriction. 4. At a higher dose (1 micro mol/L) dipyridamole potentiated vasoconstrictor responses to noradrenaline (0.03-1 nmol). At any doses used, dipyridamole had no effect on the vasoconstrictor responses to ATP (0.03-1 micro mol). 5. Tyramine (0.01-0.3 micro mol) induced vasoconstriction in a dose-dependent manner. The dose-response curves for tyramine were shifted to the right following treatment with dipyridamole (0.1-1 micro mol/L). 6. The present results indicate that dipyridamole may inhibit purinergic and adrenergic transmission presynaptically, whereas postsynaptically dipyridamole may potentiate the adrenergic vascular constriction by inhibition of transmitter uptake." @default.
- W2118049964 created "2016-06-24" @default.
- W2118049964 creator A5042316580 @default.
- W2118049964 creator A5055590397 @default.
- W2118049964 creator A5058860533 @default.
- W2118049964 date "2004-02-19" @default.
- W2118049964 modified "2023-10-15" @default.
- W2118049964 title "MODIFICATION OF TRANSMITTER RELEASE FROM PERIARTERIAL NERVE TERMINALS BY DIPYRIDAMOLE IN CANINE ISOLATED SPLENIC ARTERY" @default.
- W2118049964 cites W1947888345 @default.
- W2118049964 cites W1966453361 @default.
- W2118049964 cites W1967883006 @default.
- W2118049964 cites W1975224743 @default.
- W2118049964 cites W1985308160 @default.
- W2118049964 cites W1997411301 @default.
- W2118049964 cites W2007948756 @default.
- W2118049964 cites W2010171388 @default.
- W2118049964 cites W2023171075 @default.
- W2118049964 cites W2024103005 @default.
- W2118049964 cites W2026780812 @default.
- W2118049964 cites W2035316747 @default.
- W2118049964 cites W2041943111 @default.
- W2118049964 cites W2053225928 @default.
- W2118049964 cites W2053252257 @default.
- W2118049964 cites W2054262206 @default.
- W2118049964 cites W2054794736 @default.
- W2118049964 cites W2057607055 @default.
- W2118049964 cites W2066551451 @default.
- W2118049964 cites W2077733164 @default.
- W2118049964 cites W2081635279 @default.
- W2118049964 cites W2086213286 @default.
- W2118049964 cites W2087978298 @default.
- W2118049964 cites W2094388830 @default.
- W2118049964 cites W2097161324 @default.
- W2118049964 cites W2148815991 @default.
- W2118049964 cites W2085193842 @default.
- W2118049964 doi "https://doi.org/10.1111/j.1440-1681.2004.03969.x" @default.
- W2118049964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15008963" @default.
- W2118049964 hasPublicationYear "2004" @default.
- W2118049964 type Work @default.
- W2118049964 sameAs 2118049964 @default.
- W2118049964 citedByCount "4" @default.
- W2118049964 countsByYear W21180499642018 @default.
- W2118049964 crossrefType "journal-article" @default.
- W2118049964 hasAuthorship W2118049964A5042316580 @default.
- W2118049964 hasAuthorship W2118049964A5055590397 @default.
- W2118049964 hasAuthorship W2118049964A5058860533 @default.
- W2118049964 hasConcept C126322002 @default.
- W2118049964 hasConcept C134018914 @default.
- W2118049964 hasConcept C158453852 @default.
- W2118049964 hasConcept C170493617 @default.
- W2118049964 hasConcept C174940676 @default.
- W2118049964 hasConcept C185592680 @default.
- W2118049964 hasConcept C24998067 @default.
- W2118049964 hasConcept C2776077682 @default.
- W2118049964 hasConcept C2776890861 @default.
- W2118049964 hasConcept C2776991684 @default.
- W2118049964 hasConcept C2779961880 @default.
- W2118049964 hasConcept C42219234 @default.
- W2118049964 hasConcept C57306754 @default.
- W2118049964 hasConcept C71924100 @default.
- W2118049964 hasConcept C98274493 @default.
- W2118049964 hasConceptScore W2118049964C126322002 @default.
- W2118049964 hasConceptScore W2118049964C134018914 @default.
- W2118049964 hasConceptScore W2118049964C158453852 @default.
- W2118049964 hasConceptScore W2118049964C170493617 @default.
- W2118049964 hasConceptScore W2118049964C174940676 @default.
- W2118049964 hasConceptScore W2118049964C185592680 @default.
- W2118049964 hasConceptScore W2118049964C24998067 @default.
- W2118049964 hasConceptScore W2118049964C2776077682 @default.
- W2118049964 hasConceptScore W2118049964C2776890861 @default.
- W2118049964 hasConceptScore W2118049964C2776991684 @default.
- W2118049964 hasConceptScore W2118049964C2779961880 @default.
- W2118049964 hasConceptScore W2118049964C42219234 @default.
- W2118049964 hasConceptScore W2118049964C57306754 @default.
- W2118049964 hasConceptScore W2118049964C71924100 @default.
- W2118049964 hasConceptScore W2118049964C98274493 @default.
- W2118049964 hasIssue "3" @default.
- W2118049964 hasLocation W21180499641 @default.
- W2118049964 hasLocation W21180499642 @default.
- W2118049964 hasOpenAccess W2118049964 @default.
- W2118049964 hasPrimaryLocation W21180499641 @default.
- W2118049964 hasRelatedWork W202887539 @default.
- W2118049964 hasRelatedWork W2034716738 @default.
- W2118049964 hasRelatedWork W2057265329 @default.
- W2118049964 hasRelatedWork W2077834776 @default.
- W2118049964 hasRelatedWork W2353419483 @default.
- W2118049964 hasRelatedWork W2362510291 @default.
- W2118049964 hasRelatedWork W2368504782 @default.
- W2118049964 hasRelatedWork W2407726843 @default.
- W2118049964 hasRelatedWork W3147643987 @default.
- W2118049964 hasRelatedWork W2347468046 @default.
- W2118049964 hasVolume "31" @default.
- W2118049964 isParatext "false" @default.
- W2118049964 isRetracted "false" @default.
- W2118049964 magId "2118049964" @default.
- W2118049964 workType "article" @default.