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• W2118063923 abstract "Biomarkers reflective of disease activity in cystic fibrosis (CF) have the potential to improve patient care, particularly during CF pulmonary exacerbations (CFPEs). Although blood-based biomarkers have been studied in CFPE for nearly 3 decades, none have been integrated into routine clinical practice. To facilitate progress in this area, we performed a systematic review evaluating blood-based biomarkers during CFPE.MEDLINE, EMBASE, and CENTRAL were searched to identify relevant studies published from January 1995 to August 2012. We included all full-text studies examining systemic (blood-based) biomarkers to aid in the diagnosis of CFPE, predict outcomes of CFPE, and/or monitor the response to CFPE treatment.Seventy-eight unique blood-based biomarkers have been studied to date, mainly inflammatory cytokines, acute phase reactants, and markers of oxidative stress. C-reactive protein (CRP) consistently correlated with disease activity, with a statistically significant increase from stable to exacerbation state in five of six studies, and changes in response to CFPE treatment, with a statistically significant decrease from the beginning to the end of CFPE treatment in 18 of 20 studies. Other promising biomarkers of CFPE disease activity include neutrophil elastase antiproteinase complex, IL-6, myeloperoxidase (MPO), lactoferrin, and calprotectin.Although there are several blood-based biomarkers with evidence for application within the CFPE setting, CRP has been the most widely studied biomarker demonstrating the potential for clinical usefulness. Further validation studies and clinical trials are required to determine whether blood-based biomarkers can be used to ultimately improve health outcomes in the setting of a CFPE." @default.
• W2118063923 created "2016-06-24" @default.
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• W2118063923 creator A5073331581 @default.
• W2118063923 date "2013-11-01" @default.
• W2118063923 modified "2023-09-29" @default.
• W2118063923 title "Systematic Review of Blood Biomarkers in Cystic Fibrosis Pulmonary Exacerbations" @default.
• W2118063923 cites W1904652721 @default.
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• W2118063923 cites W1973996156 @default.
• W2118063923 cites W1979423827 @default.
• W2118063923 cites W1994733853 @default.
• W2118063923 cites W1994751767 @default.
• W2118063923 cites W1996565956 @default.
• W2118063923 cites W1996762073 @default.
• W2118063923 cites W1996804057 @default.
• W2118063923 cites W1999332213 @default.
• W2118063923 cites W2000410770 @default.
• W2118063923 cites W2001413741 @default.
• W2118063923 cites W2001587323 @default.
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• W2118063923 cites W2005501262 @default.
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• W2118063923 cites W2028341547 @default.
• W2118063923 cites W2031533581 @default.
• W2118063923 cites W2035532601 @default.
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• W2118063923 cites W2070896178 @default.
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• W2118063923 doi "https://doi.org/10.1378/chest.13-0693" @default.
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