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- W2118079678 abstract "Chronic inflammation of the vascular endothelium produces endothelial dysfunction and ultimately atherogenesis. Postprandial hyperlipidaemia is an independent risk factor for cardiovascular disease. Recent studies show that the magnitude of postprandial lipaemia following a single fatty meal is negatively related to vascular function. This is associated with a transient increase in the concentrations of pro-inflammatory cytokines and soluble adhesion molecules and in pro-oxidant activity. One possible interpretation is that repeated exposure of the blood vessel wall to the activities of pro-inflammatory cytokines and pro-oxidants may damage the vascular endothelium and promote atherogenesis. Based on these results, we propose a model of a causal mechanism to explain how consumption of a fatty meal may impair vascular dysfunction." @default.
- W2118079678 created "2016-06-24" @default.
- W2118079678 creator A5074645101 @default.
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- W2118079678 date "2005-01-01" @default.
- W2118079678 modified "2023-10-18" @default.
- W2118079678 title "Plasma cytokine response during the postprandial period: a potential causal process in vascular disease?" @default.
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- W2118079678 doi "https://doi.org/10.1079/bjn20041282" @default.
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