Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118123721> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2118123721 endingPage "2082" @default.
- W2118123721 startingPage "2080" @default.
- W2118123721 abstract "Positron emission tomography (PET) was used to examine whether the dose of pindolol used to augment antidepressant medication achieves a significant occupancy of the serotonin type 1A (5-HT(1A)) autoreceptor in depressed patients receiving medication.The authors examined eight depressed patients on one of two regimes of pindolol (2.5 mg t.i.d. and 5.0 mg t.i.d.) with PET and [11C]WAY-100635.The 5-mg t.i.d. regime achieved a modest (19%) but significant occupancy of the 5-HT(1A) autoreceptor, while the regime used in the vast majority of clinical trials (2.5 mg t.i.d.) did not achieve a significant occupancy.The dose of pindolol used in clinical trials is suboptimal and may explain the inconsistent results. Therefore, a thorough test of pindolol's efficacy will necessitate doses higher than those used in present clinical trials." @default.
- W2118123721 created "2016-06-24" @default.
- W2118123721 creator A5000083094 @default.
- W2118123721 creator A5005098704 @default.
- W2118123721 creator A5022071408 @default.
- W2118123721 creator A5023209431 @default.
- W2118123721 creator A5065874626 @default.
- W2118123721 creator A5073354341 @default.
- W2118123721 creator A5081837367 @default.
- W2118123721 date "2001-12-01" @default.
- W2118123721 modified "2023-09-25" @default.
- W2118123721 title "Pindolol Augmentation of Selective Serotonin Reuptake Inhibitors: PET Evidence That the Dose Used in Clinical Trials Is Too Low" @default.
- W2118123721 cites W1955126748 @default.
- W2118123721 cites W2004852769 @default.
- W2118123721 cites W2037003575 @default.
- W2118123721 cites W2072341886 @default.
- W2118123721 cites W2072367288 @default.
- W2118123721 cites W2138538218 @default.
- W2118123721 cites W2155132989 @default.
- W2118123721 cites W2160325982 @default.
- W2118123721 doi "https://doi.org/10.1176/appi.ajp.158.12.2080" @default.
- W2118123721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11729033" @default.
- W2118123721 hasPublicationYear "2001" @default.
- W2118123721 type Work @default.
- W2118123721 sameAs 2118123721 @default.
- W2118123721 citedByCount "76" @default.
- W2118123721 countsByYear W21181237212012 @default.
- W2118123721 countsByYear W21181237212013 @default.
- W2118123721 countsByYear W21181237212014 @default.
- W2118123721 countsByYear W21181237212015 @default.
- W2118123721 countsByYear W21181237212019 @default.
- W2118123721 countsByYear W21181237212021 @default.
- W2118123721 crossrefType "journal-article" @default.
- W2118123721 hasAuthorship W2118123721A5000083094 @default.
- W2118123721 hasAuthorship W2118123721A5005098704 @default.
- W2118123721 hasAuthorship W2118123721A5022071408 @default.
- W2118123721 hasAuthorship W2118123721A5023209431 @default.
- W2118123721 hasAuthorship W2118123721A5065874626 @default.
- W2118123721 hasAuthorship W2118123721A5073354341 @default.
- W2118123721 hasAuthorship W2118123721A5081837367 @default.
- W2118123721 hasConcept C126322002 @default.
- W2118123721 hasConcept C15744967 @default.
- W2118123721 hasConcept C170493617 @default.
- W2118123721 hasConcept C2775864247 @default.
- W2118123721 hasConcept C2777828372 @default.
- W2118123721 hasConcept C2778499207 @default.
- W2118123721 hasConcept C2779177272 @default.
- W2118123721 hasConcept C2780092697 @default.
- W2118123721 hasConcept C2781161787 @default.
- W2118123721 hasConcept C31487548 @default.
- W2118123721 hasConcept C535046627 @default.
- W2118123721 hasConcept C71924100 @default.
- W2118123721 hasConcept C8439214 @default.
- W2118123721 hasConcept C98274493 @default.
- W2118123721 hasConceptScore W2118123721C126322002 @default.
- W2118123721 hasConceptScore W2118123721C15744967 @default.
- W2118123721 hasConceptScore W2118123721C170493617 @default.
- W2118123721 hasConceptScore W2118123721C2775864247 @default.
- W2118123721 hasConceptScore W2118123721C2777828372 @default.
- W2118123721 hasConceptScore W2118123721C2778499207 @default.
- W2118123721 hasConceptScore W2118123721C2779177272 @default.
- W2118123721 hasConceptScore W2118123721C2780092697 @default.
- W2118123721 hasConceptScore W2118123721C2781161787 @default.
- W2118123721 hasConceptScore W2118123721C31487548 @default.
- W2118123721 hasConceptScore W2118123721C535046627 @default.
- W2118123721 hasConceptScore W2118123721C71924100 @default.
- W2118123721 hasConceptScore W2118123721C8439214 @default.
- W2118123721 hasConceptScore W2118123721C98274493 @default.
- W2118123721 hasIssue "12" @default.
- W2118123721 hasLocation W21181237211 @default.
- W2118123721 hasLocation W21181237212 @default.
- W2118123721 hasOpenAccess W2118123721 @default.
- W2118123721 hasPrimaryLocation W21181237211 @default.
- W2118123721 hasRelatedWork W1984341364 @default.
- W2118123721 hasRelatedWork W1986897561 @default.
- W2118123721 hasRelatedWork W2004131847 @default.
- W2118123721 hasRelatedWork W2039724589 @default.
- W2118123721 hasRelatedWork W2047476622 @default.
- W2118123721 hasRelatedWork W2076884106 @default.
- W2118123721 hasRelatedWork W2080412550 @default.
- W2118123721 hasRelatedWork W2103745296 @default.
- W2118123721 hasRelatedWork W2118123721 @default.
- W2118123721 hasRelatedWork W2168720943 @default.
- W2118123721 hasVolume "158" @default.
- W2118123721 isParatext "false" @default.
- W2118123721 isRetracted "false" @default.
- W2118123721 magId "2118123721" @default.
- W2118123721 workType "article" @default.