Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118150303> ?p ?o ?g. }
- W2118150303 endingPage "20133236" @default.
- W2118150303 startingPage "20133236" @default.
- W2118150303 abstract "The evolutionary history of the Mycobacterium tuberculosis complex (MTBC) has previously been studied by analysis of sequence diversity in extant strains, but not addressed by direct examination of strain genotypes in archaeological remains. Here, we use ancient DNA sequencing to type 11 single nucleotide polymorphisms and two large sequence polymorphisms in the MTBC strains present in 10 archaeological samples from skeletons from Britain and Europe dating to the second–nineteenth centuries AD. The results enable us to assign the strains to groupings and lineages recognized in the extant MTBC. We show that at least during the eighteenth–nineteenth centuries AD, strains of M. tuberculosis belonging to different genetic groups were present in Britain at the same time, possibly even at a single location, and we present evidence for a mixed infection in at least one individual. Our study shows that ancient DNA typing applied to multiple samples can provide sufficiently detailed information to contribute to both archaeological and evolutionary knowledge of the history of tuberculosis." @default.
- W2118150303 created "2016-06-24" @default.
- W2118150303 creator A5032209447 @default.
- W2118150303 creator A5042138603 @default.
- W2118150303 creator A5073863927 @default.
- W2118150303 date "2014-04-22" @default.
- W2118150303 modified "2023-10-15" @default.
- W2118150303 title "Genotyping of ancient Mycobacterium tuberculosis strains reveals historic genetic diversity" @default.
- W2118150303 cites W1922405592 @default.
- W2118150303 cites W1966262033 @default.
- W2118150303 cites W1966717629 @default.
- W2118150303 cites W1969464199 @default.
- W2118150303 cites W1978631525 @default.
- W2118150303 cites W1985986410 @default.
- W2118150303 cites W1987017316 @default.
- W2118150303 cites W1991909065 @default.
- W2118150303 cites W1994580619 @default.
- W2118150303 cites W1997431423 @default.
- W2118150303 cites W2000705873 @default.
- W2118150303 cites W2002683556 @default.
- W2118150303 cites W2003025878 @default.
- W2118150303 cites W2021731418 @default.
- W2118150303 cites W2034029879 @default.
- W2118150303 cites W2034057002 @default.
- W2118150303 cites W2038776014 @default.
- W2118150303 cites W2044648876 @default.
- W2118150303 cites W2052515110 @default.
- W2118150303 cites W2065550694 @default.
- W2118150303 cites W2066321034 @default.
- W2118150303 cites W2071324884 @default.
- W2118150303 cites W2071490229 @default.
- W2118150303 cites W2072669929 @default.
- W2118150303 cites W2074511613 @default.
- W2118150303 cites W2081652203 @default.
- W2118150303 cites W2098157904 @default.
- W2118150303 cites W2100887397 @default.
- W2118150303 cites W2105341822 @default.
- W2118150303 cites W2106813347 @default.
- W2118150303 cites W2110484113 @default.
- W2118150303 cites W2113265821 @default.
- W2118150303 cites W2115689009 @default.
- W2118150303 cites W2118804480 @default.
- W2118150303 cites W2119222834 @default.
- W2118150303 cites W2119863420 @default.
- W2118150303 cites W2119943296 @default.
- W2118150303 cites W2122864781 @default.
- W2118150303 cites W2126568957 @default.
- W2118150303 cites W2127991349 @default.
- W2118150303 cites W2131858525 @default.
- W2118150303 cites W2132632499 @default.
- W2118150303 cites W2134558351 @default.
- W2118150303 cites W2135029894 @default.
- W2118150303 cites W2139803213 @default.
- W2118150303 cites W2142392294 @default.
- W2118150303 cites W2142620716 @default.
- W2118150303 cites W2142943401 @default.
- W2118150303 cites W2143520279 @default.
- W2118150303 cites W2144870032 @default.
- W2118150303 cites W2145407927 @default.
- W2118150303 cites W2146394261 @default.
- W2118150303 cites W2147932017 @default.
- W2118150303 cites W2152363872 @default.
- W2118150303 cites W2152434195 @default.
- W2118150303 cites W2154753506 @default.
- W2118150303 cites W2155557228 @default.
- W2118150303 cites W2156887574 @default.
- W2118150303 cites W2162371815 @default.
- W2118150303 cites W2165822919 @default.
- W2118150303 cites W2167472189 @default.
- W2118150303 cites W2225902861 @default.
- W2118150303 doi "https://doi.org/10.1098/rspb.2013.3236" @default.
- W2118150303 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3953847" @default.
- W2118150303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24573854" @default.
- W2118150303 hasPublicationYear "2014" @default.
- W2118150303 type Work @default.
- W2118150303 sameAs 2118150303 @default.
- W2118150303 citedByCount "42" @default.
- W2118150303 countsByYear W21181503032014 @default.
- W2118150303 countsByYear W21181503032015 @default.
- W2118150303 countsByYear W21181503032016 @default.
- W2118150303 countsByYear W21181503032017 @default.
- W2118150303 countsByYear W21181503032018 @default.
- W2118150303 countsByYear W21181503032019 @default.
- W2118150303 countsByYear W21181503032020 @default.
- W2118150303 countsByYear W21181503032021 @default.
- W2118150303 countsByYear W21181503032023 @default.
- W2118150303 crossrefType "journal-article" @default.
- W2118150303 hasAuthorship W2118150303A5032209447 @default.
- W2118150303 hasAuthorship W2118150303A5042138603 @default.
- W2118150303 hasAuthorship W2118150303A5073863927 @default.
- W2118150303 hasBestOaLocation W21181503031 @default.
- W2118150303 hasConcept C104317684 @default.
- W2118150303 hasConcept C135763542 @default.
- W2118150303 hasConcept C142724271 @default.
- W2118150303 hasConcept C144024400 @default.
- W2118150303 hasConcept C149923435 @default.
- W2118150303 hasConcept C178300618 @default.
- W2118150303 hasConcept C189338579 @default.