Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118158396> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2118158396 endingPage "625" @default.
- W2118158396 startingPage "625" @default.
- W2118158396 abstract "Pathologic changes in the growth plate remain unknown in Legg-Calvé-Perthes (LCP) disease. Spontaneously hypertensive rats have proven to be a good model for studying LCP disease. This study investigated the histopathologic changes and the expression of vascular endothelial growth factor in the growth plate of spontaneously hypertensive rats (SHR).Sixty SHR rats were divided into two groups: those showing osteonecrosis (SHR+n group: 32), and those showing normal ossification (SHR-n group: 28). Thirty Wister Kyoto rats served as a control. For histomorphological measurement, the length of each zone of the growth plate was measured. Cell kinetics was measured by 5-bromo-2'-deoxyuridin (BrdU) immunohistochemistry and transferase-mediated deoxyuridine triphosphate-biotin nick end labeling (TUNEL) assays. Vascular endothelial growth factor (VEGF) immunohistochemistry was used to identify of expression of VEGF.The lengths of growth plates of the SHR+n group were significantly shorter in the initial growth period than those of the other groups. The lowest proliferative rate and the highest apoptosis rate were observed in the SHR+n group at the initial growth period. The expression of VEGF in the growth plate of the SHR group was lower than the control group, and it was lower in the SHR+n group than in the SHR-n group.The growth plate of the SHR+n group was found to be affected by disease process of ischemic necrosis of the femoral head, and this might explain the relative overgrowth of the greater trochanter in the later stages of LCP disease." @default.
- W2118158396 created "2016-06-24" @default.
- W2118158396 creator A5032088387 @default.
- W2118158396 creator A5032752383 @default.
- W2118158396 creator A5073569128 @default.
- W2118158396 date "2012-01-01" @default.
- W2118158396 modified "2023-09-25" @default.
- W2118158396 title "Altered Cellular Kinetics in the Growth Plate of the Femoral Head of Spontaneously Hypertensive Rats" @default.
- W2118158396 cites W1583699618 @default.
- W2118158396 cites W1789975724 @default.
- W2118158396 cites W1966550670 @default.
- W2118158396 cites W1966654377 @default.
- W2118158396 cites W1988589417 @default.
- W2118158396 cites W1990714728 @default.
- W2118158396 cites W2020548763 @default.
- W2118158396 cites W2024168071 @default.
- W2118158396 cites W2041176431 @default.
- W2118158396 cites W2044466696 @default.
- W2118158396 cites W2044785514 @default.
- W2118158396 cites W2051737747 @default.
- W2118158396 cites W2070736285 @default.
- W2118158396 cites W2080380127 @default.
- W2118158396 cites W2081291060 @default.
- W2118158396 cites W2090565690 @default.
- W2118158396 cites W2096231727 @default.
- W2118158396 cites W2129330575 @default.
- W2118158396 cites W2130607173 @default.
- W2118158396 cites W2140923644 @default.
- W2118158396 cites W2154406884 @default.
- W2118158396 cites W2326344100 @default.
- W2118158396 doi "https://doi.org/10.3349/ymj.2012.53.3.625" @default.
- W2118158396 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3343426" @default.
- W2118158396 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22477009" @default.
- W2118158396 hasPublicationYear "2012" @default.
- W2118158396 type Work @default.
- W2118158396 sameAs 2118158396 @default.
- W2118158396 citedByCount "0" @default.
- W2118158396 crossrefType "journal-article" @default.
- W2118158396 hasAuthorship W2118158396A5032088387 @default.
- W2118158396 hasAuthorship W2118158396A5032752383 @default.
- W2118158396 hasAuthorship W2118158396A5073569128 @default.
- W2118158396 hasBestOaLocation W21181583961 @default.
- W2118158396 hasConcept C126322002 @default.
- W2118158396 hasConcept C134018914 @default.
- W2118158396 hasConcept C141071460 @default.
- W2118158396 hasConcept C167734588 @default.
- W2118158396 hasConcept C170493617 @default.
- W2118158396 hasConcept C185592680 @default.
- W2118158396 hasConcept C190283241 @default.
- W2118158396 hasConcept C196795494 @default.
- W2118158396 hasConcept C204232928 @default.
- W2118158396 hasConcept C2775960820 @default.
- W2118158396 hasConcept C2777025900 @default.
- W2118158396 hasConcept C2779100257 @default.
- W2118158396 hasConcept C55493867 @default.
- W2118158396 hasConcept C71924100 @default.
- W2118158396 hasConceptScore W2118158396C126322002 @default.
- W2118158396 hasConceptScore W2118158396C134018914 @default.
- W2118158396 hasConceptScore W2118158396C141071460 @default.
- W2118158396 hasConceptScore W2118158396C167734588 @default.
- W2118158396 hasConceptScore W2118158396C170493617 @default.
- W2118158396 hasConceptScore W2118158396C185592680 @default.
- W2118158396 hasConceptScore W2118158396C190283241 @default.
- W2118158396 hasConceptScore W2118158396C196795494 @default.
- W2118158396 hasConceptScore W2118158396C204232928 @default.
- W2118158396 hasConceptScore W2118158396C2775960820 @default.
- W2118158396 hasConceptScore W2118158396C2777025900 @default.
- W2118158396 hasConceptScore W2118158396C2779100257 @default.
- W2118158396 hasConceptScore W2118158396C55493867 @default.
- W2118158396 hasConceptScore W2118158396C71924100 @default.
- W2118158396 hasIssue "3" @default.
- W2118158396 hasLocation W21181583961 @default.
- W2118158396 hasLocation W21181583962 @default.
- W2118158396 hasLocation W21181583963 @default.
- W2118158396 hasLocation W21181583964 @default.
- W2118158396 hasOpenAccess W2118158396 @default.
- W2118158396 hasPrimaryLocation W21181583961 @default.
- W2118158396 hasRelatedWork W1553598265 @default.
- W2118158396 hasRelatedWork W2078978316 @default.
- W2118158396 hasRelatedWork W2087090518 @default.
- W2118158396 hasRelatedWork W2098742882 @default.
- W2118158396 hasRelatedWork W2368731425 @default.
- W2118158396 hasRelatedWork W2380423849 @default.
- W2118158396 hasRelatedWork W2389467880 @default.
- W2118158396 hasRelatedWork W2396486584 @default.
- W2118158396 hasRelatedWork W2747054008 @default.
- W2118158396 hasRelatedWork W4236502113 @default.
- W2118158396 hasVolume "53" @default.
- W2118158396 isParatext "false" @default.
- W2118158396 isRetracted "false" @default.
- W2118158396 magId "2118158396" @default.
- W2118158396 workType "article" @default.