Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118226504> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2118226504 endingPage "140" @default.
- W2118226504 startingPage "133" @default.
- W2118226504 abstract "Theophylline was administered in a three-way crossover design study to six cats intravenously (Aminophylline USP, Invenex Laboratories, Chagrin Falls, OH) and orally as two sustained-release formulations (Slo-bid Gyrocaps® (SB), William H. Rorer, Inc., Fort Washington, PA; Theo-Dur® Tablets (TD), Key Pharmaceuticals, Miami, FL). Values were determined for mean residence time (SB = 19.4 ± 3.2 h; TD = 15.8 ± 4.8 h), mean absorption time (SB = 8.0 ± 2.3 h; TD = 4.8 ± 2.3 h), absolute bioavailability (SB = 82 ± 27%; TD = 76 ± 38%), and time to peak plasma concentrations (SB = 8 h; TD = 8 h). After normalization to a dose of 25 mg/kg, the average peak plasma concentrations were also predicted (SB = 10.5 ± 3.4 μg/ml; TD = 14.3 ± 6.7 μg/ml). Slo-bid® was predicted to provide the least peak: trough fluctuation in theophylline concentrations. Slo-bid® and Theo-Dur® appear to have pharmacokinetic characteristics which, if given once-daily, would maintain plasma theophylline concentrations of 5–20 μg/ml in the cat." @default.
- W2118226504 created "2016-06-24" @default.
- W2118226504 creator A5029771480 @default.
- W2118226504 creator A5045098848 @default.
- W2118226504 creator A5045301240 @default.
- W2118226504 creator A5050717124 @default.
- W2118226504 creator A5074768914 @default.
- W2118226504 date "1989-06-01" @default.
- W2118226504 modified "2023-09-27" @default.
- W2118226504 title "Sustained-release theophylline pharmacokinetics in the cat" @default.
- W2118226504 cites W1975240382 @default.
- W2118226504 cites W1999495842 @default.
- W2118226504 cites W2006296595 @default.
- W2118226504 cites W2045211098 @default.
- W2118226504 cites W2059371695 @default.
- W2118226504 cites W2085840021 @default.
- W2118226504 cites W2127831740 @default.
- W2118226504 cites W2150379145 @default.
- W2118226504 cites W2164828180 @default.
- W2118226504 cites W2336612646 @default.
- W2118226504 cites W4249845327 @default.
- W2118226504 doi "https://doi.org/10.1111/j.1365-2885.1989.tb00654.x" @default.
- W2118226504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2746720" @default.
- W2118226504 hasPublicationYear "1989" @default.
- W2118226504 type Work @default.
- W2118226504 sameAs 2118226504 @default.
- W2118226504 citedByCount "11" @default.
- W2118226504 countsByYear W21182265042012 @default.
- W2118226504 countsByYear W21182265042013 @default.
- W2118226504 crossrefType "journal-article" @default.
- W2118226504 hasAuthorship W2118226504A5029771480 @default.
- W2118226504 hasAuthorship W2118226504A5045098848 @default.
- W2118226504 hasAuthorship W2118226504A5045301240 @default.
- W2118226504 hasAuthorship W2118226504A5050717124 @default.
- W2118226504 hasAuthorship W2118226504A5074768914 @default.
- W2118226504 hasConcept C112705442 @default.
- W2118226504 hasConcept C125287762 @default.
- W2118226504 hasConcept C126322002 @default.
- W2118226504 hasConcept C142724271 @default.
- W2118226504 hasConcept C159985019 @default.
- W2118226504 hasConcept C181389837 @default.
- W2118226504 hasConcept C185592680 @default.
- W2118226504 hasConcept C192562407 @default.
- W2118226504 hasConcept C204787440 @default.
- W2118226504 hasConcept C27081682 @default.
- W2118226504 hasConcept C2776042228 @default.
- W2118226504 hasConcept C2776202631 @default.
- W2118226504 hasConcept C2778095195 @default.
- W2118226504 hasConcept C2781018748 @default.
- W2118226504 hasConcept C3020079912 @default.
- W2118226504 hasConcept C55493867 @default.
- W2118226504 hasConcept C71924100 @default.
- W2118226504 hasConcept C87813604 @default.
- W2118226504 hasConcept C98274493 @default.
- W2118226504 hasConceptScore W2118226504C112705442 @default.
- W2118226504 hasConceptScore W2118226504C125287762 @default.
- W2118226504 hasConceptScore W2118226504C126322002 @default.
- W2118226504 hasConceptScore W2118226504C142724271 @default.
- W2118226504 hasConceptScore W2118226504C159985019 @default.
- W2118226504 hasConceptScore W2118226504C181389837 @default.
- W2118226504 hasConceptScore W2118226504C185592680 @default.
- W2118226504 hasConceptScore W2118226504C192562407 @default.
- W2118226504 hasConceptScore W2118226504C204787440 @default.
- W2118226504 hasConceptScore W2118226504C27081682 @default.
- W2118226504 hasConceptScore W2118226504C2776042228 @default.
- W2118226504 hasConceptScore W2118226504C2776202631 @default.
- W2118226504 hasConceptScore W2118226504C2778095195 @default.
- W2118226504 hasConceptScore W2118226504C2781018748 @default.
- W2118226504 hasConceptScore W2118226504C3020079912 @default.
- W2118226504 hasConceptScore W2118226504C55493867 @default.
- W2118226504 hasConceptScore W2118226504C71924100 @default.
- W2118226504 hasConceptScore W2118226504C87813604 @default.
- W2118226504 hasConceptScore W2118226504C98274493 @default.
- W2118226504 hasIssue "2" @default.
- W2118226504 hasLocation W21182265041 @default.
- W2118226504 hasLocation W21182265042 @default.
- W2118226504 hasOpenAccess W2118226504 @default.
- W2118226504 hasPrimaryLocation W21182265041 @default.
- W2118226504 hasRelatedWork W1970536119 @default.
- W2118226504 hasRelatedWork W1986197070 @default.
- W2118226504 hasRelatedWork W2020713464 @default.
- W2118226504 hasRelatedWork W2083610014 @default.
- W2118226504 hasRelatedWork W2084824126 @default.
- W2118226504 hasRelatedWork W2390358224 @default.
- W2118226504 hasRelatedWork W2399112385 @default.
- W2118226504 hasRelatedWork W2399240216 @default.
- W2118226504 hasRelatedWork W2419272372 @default.
- W2118226504 hasRelatedWork W2462873895 @default.
- W2118226504 hasVolume "12" @default.
- W2118226504 isParatext "false" @default.
- W2118226504 isRetracted "false" @default.
- W2118226504 magId "2118226504" @default.
- W2118226504 workType "article" @default.