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- W211830781 abstract "Behavioral study of pro-opiomelanocortin products indicates that beta-endorphin and corticotrophin-like peptides have antagonistic effects. However, these peptides have similar actions on the rat vas deferens. beta-endorphin, alpha-MSH and ACTH each inhibit electrically evoked contraction of the duct, but the corticotrophin derived peptides are tenfold more potent on a molar basis (ED50 = 9 nM). Pharmacological analysis shows that the action of corticotrophin-derived peptides does not involve an opiate receptor mechanism. The results are discussed in terms of the central action of the peptides." @default.
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- W211830781 date "1986-11-01" @default.
- W211830781 modified "2023-09-26" @default.
- W211830781 title "Action of pro-opiomelanocortin products on the rat" @default.
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- W211830781 doi "https://doi.org/10.1016/0024-3205(86)90162-1" @default.
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