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• W2118329596 abstract "The concept that the brain can control the peripheral responses of the body was first suggested by Oliver Wendell Holmes who stated, “It has often been found that the same wound received in battle will do well in the soldiers that have beaten, that would prove fatal in those that have just been defeated.” The first experimental evidence was produced by Matalnikov and Chorine at the Pasteur Institute in Paris. When using Pavlovian techniques in dogs, he showed that classical conditioning modulates immunity. 1 Matalnikov S. Chorine V. Classical conditioning modulates immunity. Ann Inst Pasteur. 1926; 11: 1-8 Google Scholar In 1975, Ader and Cohen 2 Ader R. Cohen N. Behaviorally conditioned immunosuppression. Psychosom Med. 1975; 37: 333-340 Crossref PubMed Scopus (643) Google Scholar showed that pairing saccharin with cyclophosphamide not only resulted in taste aversion but that future exposures to saccharin led to immunosuppression on subsequent exposure to saccharin. Before this, Moos and Solomon 3 Moos R.H. Solomon G.F. Personality correlates of the rapidity of progression of rheumatoid arthritis. Ann Rheum Dis. 1964; 23: 145-151 Crossref PubMed Scopus (30) Google Scholar had demonstrated that personality determines the progress of rheumatoid arthritis. They suggested that this new field should be termed, “psychoimmunology” and was deserving of intensive study. George Valiant, in his pioneering studies, showed that 2 major components of aging successfully were coping skills (the ability to manage stress well) and the importance of enjoying a stable relationship. 4 Vaillant G.E. Triumphs of Experience: The Men of the Harvard Grant Study. Harvard University Press, Cambridge, MA2012 Crossref Google Scholar" @default.
• W2118329596 created "2016-06-24" @default.
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• W2118329596 date "2015-11-01" @default.
• W2118329596 modified "2023-09-25" @default.
• W2118329596 title "Psychoimmunology and Aging: A Tribute to George Freeman Solomon" @default.
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• W2118329596 doi "https://doi.org/10.1016/j.jamda.2015.08.024" @default.
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