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- W2118429304 abstract "Aim : To explore the association between NAFLD and MetS, and to clarify the difference of glucose metabolism between MetS with and without NAFLD. Methods : In this paper, we explore the association between NAFLD and MetS from the viewpoint of clinical characters and discuss the difference of abnormal glucose metabolism in the etiology of NAFLD and MetS, which based on metabolic profiling of urinary carbohydrates using gas chromatography/mass spectrometry (GC/MS) and multivariate statistical analysis with Model Population Analysis (MPA) based Support Vector Machines (SVMs). Results : The BMI, waist circumference, hip circumference, WHR and diastolic blood pressure in MetS patients with NAFLD were significantly higher than patients without NAFLD ( P 0.05). Consequently, two potential biomarkers, Glucose and Inositol A, were discovered in the two groups using MPA/SVM and kruskal-Wallis test. Conclusion : This research shows the incidence of abdominal obese and hyperlipidemia to be significantly higher in MetS patients with NAFLD than that observed in those without NAFLD. Moreover, the higher glycated hemoglobin in MetS patients with NAFLD suggests the poorer abnormal glucose metabolism. Furthermore, according the GC/MS combined with MPA/SVM, the two groups could be separated apparently from the glucose data, and two differential metabolites including Glucose and Inositol A are found." @default.
- W2118429304 created "2016-06-24" @default.
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- W2118429304 date "2014-01-01" @default.
- W2118429304 modified "2023-09-22" @default.
- W2118429304 title "The Glucose Metabolism in Metabolic Syndrome Patients with Non-Alcoholic Fatty Liver Disease" @default.
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- W2118429304 doi "https://doi.org/10.12970/2308-6483.2014.02.01.4" @default.
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