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• W2118499275 abstract "OBJECTIVE- to conduct a cultural adaptation and test the psychometric properties of the MSTCQ © (“ MS Treatment Concerns Questionnaire ”) Spanish language version. This tool evaluates atisfaction with the injection device (DI) for the treatment of Multiple Sclerosis (MS) in 4 dimensions: Injection system(A), Side-effects(B) (flu-like symptoms, reactions, and satisfaction), Treatment experience(C) and Benefits(D).BACKGROUND- Albeit effectiveness of injected treatments for MS, adverse reactions and pain may involve continuity and Satisfaction problems. We carried out this study in order to meet the need for specific instruments in measuring patient satisfaction with treatment MS in spanish language.DESIGN/METHODS-Two stages: 1)Cultural adaptation: Forward-backward translation, translation panels, and expert (n=6) and patient (n=27) panels; 2)Validation: Observational, cross-sectional, multicenter study, , 7-month long study. Adult patients suffering from MS and using an injection device were evaluated in a single visit (n=143). Questionnaires: MSTCQ © , Patient-Reported Indices for MS (PRIMUS © ), Treatment Satisfaction Questionnaire for Medication( TSQM © ). Psychometric properties: Feasibility (% valid cases and ground/ceiling effects); Reliability (Cronbach α) and test-retest (41 patients, Intraclass Correlation Coefficient, ICC); as well as construct (Factorial analysis of dimensions A and B, FA) and convergent (Spearman MSTCQ vs. TSQM) validity.RESULTS- Mean age(SD) in cases was 41.94(10.47) years, 63%female, 88.11% suffering from Relapsing-Remitting MS, EDSS mean(SD) was 2.68(1.82). MSTCQ feasibility was adequate (missing 0%-2.80%). High internal consistency, total score (A+B) α =0.89, by dimensions α (A, B and C): 0.76, 0.89 and 0.92, respectively. Very good accordance was found between total (ICC= 0.98) and by dimensions ICC (A, B and C) scores: 0.82, 0.97 and 0.89, respectively. The FA confirms dimensions A and B from the original questionnaire. Lastly, the association between total and by dimensions scores, from MSTCQ and TSQM was,overall, moderately strong (Rho 0.74-0.42) and significant (p<0.05; p<0.01).CONCLUSIONS-The Spanish version of the MSTCQ questionnaire observes adequate psychometric properties (feasibility, reliability, construct and criterion validity).Supported by: Novartis Espana Disclosure: Dr. Munteis has received personal compensation for activities with Teva Neuroscience, Sanofi-Aventis Pharmaceuticals Inc., Merck Serono, Bayer Pharmaceuticals Inc., Biogen Idec and Novartis. Dr. Guillermo has nothing to disclose. Dr. Meca La Llana has received personal compensation for activities with Teva Neuroscience, as well as other pharmaceutical companies. Dr. Maestre Martinez has nothing to disclose. Dr. Sempere has received personal compensation for activities with Biogen Idec, Bayer Schering, Merck Serono, Novartis, Sanofi-Aventis Pharmaceuticals Inc., and Teva Neuroscience. Dr. Gracia has nothing to disclose. Dr. Pato has nothing to disclose." @default.
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• W2118499275 date "2014-04-08" @default.
• W2118499275 modified "2023-10-01" @default.
• W2118499275 title "Cultural Adaptation and Evaluation of the Psychometric Properties of the MSTCQ© “MS Treatment Concerns Questionnaire” Spanish Language Version (P3.141)" @default.
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