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- W2118501188 abstract "<h3>OBJECTIVE</h3> To determine the value of surgical closure of atrial septal defects in patients over 40 years of age. <h3>METHODS</h3> Retrospective analysis of 76 patients (63 women, 13 men), age range 40–62 years (mean (SD) 45.8 (5.1) years), who underwent surgical repair of atrial septal defect. Pre- and postoperative clinical status (New York Heart Association (NYHA) functional class) was assessed, and ECG,<i>x</i> ray, and echocardiographic investigations performed. Follow up was between 1 and 17 years. <h3>RESULTS</h3> One operative and one late death occurred during the study period. Before operation, 47 patients (61.8%) were in NYHA functional classes III and IV. After operation, 61 patients (82.4%) were in classes I and II. Four patients had atrial fibrillation before surgery versus nine after surgery. Before operation, 52 patients had intensified pulmonary vascularity compared with only seven after operation. Echocardiographic examination showed a significant reduction in right ventricular dimension (4.10 (0.91)<i>v</i> 2.95 (0.36) cm, p < 0.001). No residual intracardiac shunts were identified on echocardiographic follow up. <h3>CONCLUSIONS</h3> Surgical closure of atrial septal defects in patients over 40 years old can improve their clinical status and prevent right ventricular dilatation and insufficiency." @default.
- W2118501188 created "2016-06-24" @default.
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- W2118501188 date "2001-03-01" @default.
- W2118501188 modified "2023-09-25" @default.
- W2118501188 title "Do patients over 40 years of age benefit from surgical closure of atrial septal defects?" @default.
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- W2118501188 doi "https://doi.org/10.1136/heart.85.3.300" @default.
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