FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118515054> ?p ?o ?g. }

• W2118515054 endingPage "72" @default.
• W2118515054 startingPage "664" @default.
• W2118515054 abstract "PHILIP C. MERKER AND GEORGE W. WOOLLEY (Division of Human Tumor Experimental Chemotherapy, Sloan-Kettering Institute for Cancer Research, and Sloan-Kettering Division, CorneU University Medical College, New York, N.Y.) A recent review of heterologous transplantation of cancer (1) emphasizes the growing importance of this field to cancer research. Heterologous trans- plant systems with human tumors have been only developed recently to evaluate the potential anti- cancer activity of various agents. The embryo- nated chicken egg (10-12, 22, 23), x-radiated and cortisone-treated rat (3, 34, 35, 43, 44, 45, 49), cortisone-treated hamster (21), guinea pig (31), and hatched chick (40) bearing human tumors have been used in various studies. However, mice transplanted with human cancerous tissue have not been used for chemotherapy investigations, although human tumor transplants have been grown m this species. Iversen (25, 26), Ageenko (2), Lumb (33), Chesterman (9), Green and Whiteley (17), Herbut and Kraemer (24), and Krementz and Kohame (31) have used condi- tioned mice to grow human neoplastic tissue with variable degrees of success. Handler (20) used mice bearing ACTH-secreting pituitary tumors to grow human tumors. Greene (18, 19) has grown human cancers in the eye and brain of uncondi- tioned mice, and it has been reported that human cancerous tissue has been grown successfully in un- conditioned mice in sites other than the eye and brain after passage of the tissue through several generations of pregnant mice (27, 38). Toolan (46, 47) and Gallily and Woolley (15) have reported that H.Ep. #3, a human epidermoid carcinoma, readily grows in conditioned Swiss mice. In view of the availability of H.Ep. #3 tumor at Sloan- Kettering Institute and the background of ira- *This study was supported in part by a research grant CY-3784 from the National Cancer Institute, National In- stitutes of Health, U.S. Public Health Service, Bethesda, Md. ; in part by a contract SA-43-ph-1953 from the Cancer Chemo- therapy Service Center, Bethesda, Md.; and in part by a grant 1-47 from the American Cancer Society. Received for publication February 9, 1959. munological (28-30, 49, 50), biochemical (5-8, 14), chromosomal (32), and transplantation (37, 40) in- formation reported for this tumor, Swiss mice transplanted with H.Ep. #3 were chosen as an experimental model to investigate the applicabil- ity of the conditioned mouse, bearing human tumor transplants, to experimental chemotherapy studies. MATERIALS AND METHODS Female Swiss Webster mice (Taconie Farms) weighing 15-22 gin. were used as hosts. Since three tumors, each having a minimum weight of 2.0 gm., were required for setting up chemotherapy and other experimental groups, and because of the difficulty in maintaining a continuous transplant line in Swiss mice" @default.
• W2118515054 created "2016-06-24" @default.
• W2118515054 creator A5015277076 @default.
• W2118515054 creator A5018892213 @default.
• W2118515054 date "1959-07-01" @default.
• W2118515054 modified "2023-09-23" @default.
• W2118515054 title "A study of human epidermoid carcinoma (H.Ep.#3) growing in conditioned Swiss mice. I. Applicability to chemotherapy studies." @default.
• W2118515054 cites W1495659222 @default.
• W2118515054 cites W1531260154 @default.
• W2118515054 cites W1533562323 @default.
• W2118515054 cites W1551904537 @default.
• W2118515054 cites W1552301765 @default.
• W2118515054 cites W1563616622 @default.
• W2118515054 cites W1579642535 @default.
• W2118515054 cites W1594075697 @default.
• W2118515054 cites W1773303630 @default.
• W2118515054 cites W1977584773 @default.
• W2118515054 cites W1994120165 @default.
• W2118515054 cites W2009693695 @default.
• W2118515054 cites W2015977539 @default.
• W2118515054 cites W2023143648 @default.
• W2118515054 cites W2058499942 @default.
• W2118515054 cites W2089045926 @default.
• W2118515054 cites W2096266700 @default.
• W2118515054 cites W2104666455 @default.
• W2118515054 cites W2106192732 @default.
• W2118515054 cites W2121852654 @default.
• W2118515054 cites W2315913278 @default.
• W2118515054 cites W2317593560 @default.
• W2118515054 cites W2399576853 @default.
• W2118515054 cites W2416445943 @default.
• W2118515054 cites W2425037246 @default.
• W2118515054 cites W2440095077 @default.
• W2118515054 cites W2626162448 @default.
• W2118515054 cites W606392921 @default.
• W2118515054 cites W78662259 @default.
• W2118515054 cites W1545042102 @default.
• W2118515054 cites W1609362914 @default.
• W2118515054 cites W1828608695 @default.
• W2118515054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13671429" @default.
• W2118515054 hasPublicationYear "1959" @default.
• W2118515054 type Work @default.
• W2118515054 sameAs 2118515054 @default.
• W2118515054 citedByCount "4" @default.
• W2118515054 crossrefType "journal-article" @default.
• W2118515054 hasAuthorship W2118515054A5015277076 @default.
• W2118515054 hasAuthorship W2118515054A5018892213 @default.
• W2118515054 hasConcept C104317684 @default.
• W2118515054 hasConcept C121608353 @default.
• W2118515054 hasConcept C126322002 @default.
• W2118515054 hasConcept C142724271 @default.
• W2118515054 hasConcept C2776694085 @default.
• W2118515054 hasConcept C2780115692 @default.
• W2118515054 hasConcept C2911091166 @default.
• W2118515054 hasConcept C502942594 @default.
• W2118515054 hasConcept C54355233 @default.
• W2118515054 hasConcept C71924100 @default.
• W2118515054 hasConcept C86803240 @default.
• W2118515054 hasConceptScore W2118515054C104317684 @default.
• W2118515054 hasConceptScore W2118515054C121608353 @default.
• W2118515054 hasConceptScore W2118515054C126322002 @default.
• W2118515054 hasConceptScore W2118515054C142724271 @default.
• W2118515054 hasConceptScore W2118515054C2776694085 @default.
• W2118515054 hasConceptScore W2118515054C2780115692 @default.
• W2118515054 hasConceptScore W2118515054C2911091166 @default.
• W2118515054 hasConceptScore W2118515054C502942594 @default.
• W2118515054 hasConceptScore W2118515054C54355233 @default.
• W2118515054 hasConceptScore W2118515054C71924100 @default.
• W2118515054 hasConceptScore W2118515054C86803240 @default.
• W2118515054 hasIssue "6, Part 1" @default.
• W2118515054 hasLocation W21185150541 @default.
• W2118515054 hasOpenAccess W2118515054 @default.
• W2118515054 hasPrimaryLocation W21185150541 @default.
• W2118515054 hasRelatedWork W1966540572 @default.
• W2118515054 hasRelatedWork W216643347 @default.
• W2118515054 hasRelatedWork W2296094089 @default.
• W2118515054 hasRelatedWork W2365364931 @default.
• W2118515054 hasRelatedWork W2366500105 @default.
• W2118515054 hasRelatedWork W2371666691 @default.
• W2118515054 hasRelatedWork W2378355431 @default.
• W2118515054 hasRelatedWork W2396099507 @default.
• W2118515054 hasRelatedWork W4232637051 @default.
• W2118515054 hasRelatedWork W2092874662 @default.
• W2118515054 hasVolume "19" @default.
• W2118515054 isParatext "false" @default.
• W2118515054 isRetracted "false" @default.
• W2118515054 magId "2118515054" @default.
• W2118515054 workType "article" @default.