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- W2118572012 abstract "Parameters of cell-mediated and humoral immunity were examined in 8 patients with clinically inactive SLE undergoing levamisole treatment. Lymphocyte transformation with PHA and PMW was temporarily increased in the first month of therapy; at the same time absolute numbers of peripheral blood lymphocytes, T cells and B cells increased slightly. However, these differences were not significant statistically. In 1 patient with a diminished percentage of T cells and an increased percentage of B cells, levamisole induced normalization. Antibodies to DNA decreased in 6 patients, while litres of ANA decreased only in one patient. Serum levels of Clq and C3 increased in 7 and 3 patients, respectively. Four patients were treated with levamisole for 12 months, during which time there was neither clinical exacerbation nor deterioration of renal function and the concomitant corticosteroid therapy could be reduced." @default.
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- W2118572012 date "1980-01-01" @default.
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- W2118572012 title "Effect of Levamisole on Immunological Parameters in Patients with Systemic Lupus Erythematosus" @default.
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- W2118572012 doi "https://doi.org/10.3109/03009748009098138" @default.
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