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- W2118601935 endingPage "375" @default.
- W2118601935 startingPage "359" @default.
- W2118601935 abstract "Chronic hepatitis C remains a significant medical and economic burden in Canada, affecting nearly 1% of the population. Since the last consensus conference on the management of chronic hepatitis C, major advances have warranted a review of recommended management approaches for these patients. Specifically, direct-acting antiviral agents with dramatically improved rates of virological clearance compared with standard therapy have been developed, and several single nucleotide polymorphisms associated with an increased probability of spontaneous and treatment-induced viral clearance have been identified. In light of this new evidence, a consensus development conference was held in November 2011; the present document highlights the results of the presentations and discussions surrounding these issues. It reviews the epidemiology of hepatitis C in Canada, preferred diagnostic testing approaches and recommendations for the treatment of chronically infected patients with the newly approved protease inhibitors (boceprevir and telaprevir), including those who have previously failed pegylated interferon and ribavirin therapy. In addition, recommendations are made regarding approaches to reducing the burden of hepatitis C in Canada." @default.
- W2118601935 created "2016-06-24" @default.
- W2118601935 creator A5013219986 @default.
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- W2118601935 creator A5025087427 @default.
- W2118601935 creator A5048201114 @default.
- W2118601935 creator A5049864482 @default.
- W2118601935 date "2012-01-01" @default.
- W2118601935 modified "2023-10-12" @default.
- W2118601935 title "An Update on the Management of Chronic Hepatitis C: Consensus Guidelines from the Canadian Association for the Study of the Liver" @default.
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