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• W2118610143 abstract "Restricted accessMoreSectionsView PDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InRedditEmail Cite this article Pybus Oliver G. and Harvey Paul H. 2000Testing macro–evolutionary models using incomplete molecular phylogeniesProc. R. Soc. Lond. B.2672267–2272http://doi.org/10.1098/rspb.2000.1278SectionRestricted accessTesting macro–evolutionary models using incomplete molecular phylogenies Oliver G. Pybus Oliver G. Pybus Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK [email protected] Google Scholar Find this author on PubMed Search for more papers by this author and Paul H. Harvey Paul H. Harvey Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK Google Scholar Find this author on PubMed Search for more papers by this author Oliver G. Pybus Oliver G. Pybus Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK [email protected] Google Scholar Find this author on PubMed Search for more papers by this author and Paul H. Harvey Paul H. Harvey Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK Google Scholar Find this author on PubMed Search for more papers by this author Published:22 November 2000https://doi.org/10.1098/rspb.2000.1278AbstractPhylogenies reconstructed from gene sequences can be used to investigate the tempo and mode of species diversification. Here we develop and use new statistical methods to infer past patterns of speciation and extinction from molecular phylogenies. Specifically, we test the null hypothesis that per–lineage speciation and extinction rates have remained constant through time. Rejection of this hypothesis may provide evidence for evolutionary events such as adaptive radiations or key adaptations. In contrast to previous approaches, our methods are robust to incomplete taxon sampling and are conservative with respect to extinction. Using simulation we investigate, first, the adverse effects of failing to take incomplete sampling into account and, second, the power and reliability of our tests. When applied to published phylogenies our tests suggest that, in some cases, speciation rates have decreased through time. Previous ArticleNext Article VIEW FULL TEXT DOWNLOAD PDF FiguresRelatedReferencesDetailsCited by López-Córdova D, Avaria-Llautureo J, Ulloa P, Braid H, Revell L, Fuchs D and Ibáñez C (2022) Mesozoic origin of coleoid cephalopods and their abrupt shifts of diversification patterns, Molecular Phylogenetics and Evolution, 10.1016/j.ympev.2021.107331, 166, (107331), Online publication date: 1-Jan-2022. 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