FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118611544> ?p ?o ?g. }

• W2118611544 endingPage "361" @default.
• W2118611544 startingPage "361" @default.
• W2118611544 abstract "To validate pharmacologically the feline model of steroid-induced ocular hypertension.Serial studies were conducted in domesticated adult female cats trained to accept topical ocular drug administration and pneumotonometry. To establish intraocular pressure (IOP) values for each study, measurements were performed at the same time of day for 6 consecutive days. Beginning on day 7, cats received either steroid or vehicle administered topically to both eyes three times a day for approximately 28 days. The IOP measurements were performed daily.After 5 to 7 days of treatment with 0.1% dexamethasone or 1.0% prednisolone acetate, IOP began to increase, reaching peak values within 2 weeks. These values were sustained throughout dosing but declined rapidly to baseline upon cessation of treatment. Maximum IOPs for the dexamethasone- and prednisolone-treated groups averaged 4.5 +/- 0.3 mm Hg (n = 12) greater than the mean IOP value obtained in vehicle-treated cats. Cats treated with 0.25% fluorometholone, 1.0% loteprednol etabonate, and 1.0% rimexolone exhibited increases of 0.6, 1.2, and 1.7 mm Hg, respectively. These values were significantly lower than those observed following treatment with dexamethasone or prednisolone.The ocular hypertensive effects of selected anti-inflammatory topical ocular steroids in this model are consistent with clinical findings.This feline model is a useful tool for assessing the potential IOP liability of novel anti-inflammatory steroids." @default.
• W2118611544 created "2016-06-24" @default.
• W2118611544 creator A5018395306 @default.
• W2118611544 creator A5027226654 @default.
• W2118611544 creator A5028252169 @default.
• W2118611544 creator A5053138647 @default.
• W2118611544 creator A5063244514 @default.
• W2118611544 date "1999-03-01" @default.
• W2118611544 modified "2023-10-14" @default.
• W2118611544 title "Pharmacological Validation of a Feline Model of Steroid-Induced Ocular Hypertension" @default.
• W2118611544 cites W17419255 @default.
• W2118611544 cites W1982215405 @default.
• W2118611544 cites W2007070378 @default.
• W2118611544 cites W2015820640 @default.
• W2118611544 cites W2016317689 @default.
• W2118611544 cites W2017038346 @default.
• W2118611544 cites W2023036475 @default.
• W2118611544 cites W2040915940 @default.
• W2118611544 cites W2051279485 @default.
• W2118611544 cites W2056182686 @default.
• W2118611544 cites W2060996384 @default.
• W2118611544 cites W2087202735 @default.
• W2118611544 cites W2092901752 @default.
• W2118611544 cites W2140554119 @default.
• W2118611544 cites W2141969663 @default.
• W2118611544 cites W2469898569 @default.
• W2118611544 cites W96503828 @default.
• W2118611544 cites W1597473244 @default.
• W2118611544 cites W1979552814 @default.
• W2118611544 doi "https://doi.org/10.1001/archopht.117.3.361" @default.
• W2118611544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10088814" @default.
• W2118611544 hasPublicationYear "1999" @default.
• W2118611544 type Work @default.
• W2118611544 sameAs 2118611544 @default.
• W2118611544 citedByCount "37" @default.
• W2118611544 countsByYear W21186115442013 @default.
• W2118611544 countsByYear W21186115442014 @default.
• W2118611544 countsByYear W21186115442015 @default.
• W2118611544 countsByYear W21186115442016 @default.
• W2118611544 countsByYear W21186115442017 @default.
• W2118611544 countsByYear W21186115442019 @default.
• W2118611544 countsByYear W21186115442021 @default.
• W2118611544 countsByYear W21186115442022 @default.
• W2118611544 crossrefType "journal-article" @default.
• W2118611544 hasAuthorship W2118611544A5018395306 @default.
• W2118611544 hasAuthorship W2118611544A5027226654 @default.
• W2118611544 hasAuthorship W2118611544A5028252169 @default.
• W2118611544 hasAuthorship W2118611544A5053138647 @default.
• W2118611544 hasAuthorship W2118611544A5063244514 @default.
• W2118611544 hasConcept C118487528 @default.
• W2118611544 hasConcept C126322002 @default.
• W2118611544 hasConcept C141071460 @default.
• W2118611544 hasConcept C2776521421 @default.
• W2118611544 hasConcept C2776715498 @default.
• W2118611544 hasConcept C2776804153 @default.
• W2118611544 hasConcept C2777288759 @default.
• W2118611544 hasConcept C2777520566 @default.
• W2118611544 hasConcept C2779904517 @default.
• W2118611544 hasConcept C2780401358 @default.
• W2118611544 hasConcept C2780841215 @default.
• W2118611544 hasConcept C2780902042 @default.
• W2118611544 hasConcept C2781092963 @default.
• W2118611544 hasConcept C42219234 @default.
• W2118611544 hasConcept C71315377 @default.
• W2118611544 hasConcept C71924100 @default.
• W2118611544 hasConceptScore W2118611544C118487528 @default.
• W2118611544 hasConceptScore W2118611544C126322002 @default.
• W2118611544 hasConceptScore W2118611544C141071460 @default.
• W2118611544 hasConceptScore W2118611544C2776521421 @default.
• W2118611544 hasConceptScore W2118611544C2776715498 @default.
• W2118611544 hasConceptScore W2118611544C2776804153 @default.
• W2118611544 hasConceptScore W2118611544C2777288759 @default.
• W2118611544 hasConceptScore W2118611544C2777520566 @default.
• W2118611544 hasConceptScore W2118611544C2779904517 @default.
• W2118611544 hasConceptScore W2118611544C2780401358 @default.
• W2118611544 hasConceptScore W2118611544C2780841215 @default.
• W2118611544 hasConceptScore W2118611544C2780902042 @default.
• W2118611544 hasConceptScore W2118611544C2781092963 @default.
• W2118611544 hasConceptScore W2118611544C42219234 @default.
• W2118611544 hasConceptScore W2118611544C71315377 @default.
• W2118611544 hasConceptScore W2118611544C71924100 @default.
• W2118611544 hasIssue "3" @default.
• W2118611544 hasLocation W21186115441 @default.
• W2118611544 hasLocation W21186115442 @default.
• W2118611544 hasOpenAccess W2118611544 @default.
• W2118611544 hasPrimaryLocation W21186115441 @default.
• W2118611544 hasRelatedWork W2007070378 @default.
• W2118611544 hasRelatedWork W2016317689 @default.
• W2118611544 hasRelatedWork W2031691405 @default.
• W2118611544 hasRelatedWork W2095161323 @default.
• W2118611544 hasRelatedWork W2116550005 @default.
• W2118611544 hasRelatedWork W2118611544 @default.
• W2118611544 hasRelatedWork W2196877140 @default.
• W2118611544 hasRelatedWork W2319040444 @default.
• W2118611544 hasRelatedWork W2418848219 @default.
• W2118611544 hasRelatedWork W2739584381 @default.
• W2118611544 hasVolume "117" @default.
• W2118611544 isParatext "false" @default.

• next