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• W2118761991 abstract "Carotid-femoral pulse wave velocity (PWV) is considered the gold-standard measurement of arterial stiffness. Obesity, however, can render inaccurate the measurement of PWV by external noninvasive devices. Phase-contrast MRI allows the determination of aortic PWV in multiple aortic locations with intra-arterial distance measurements, as well as the assessment of aortic mechanical properties. The purpose of this study was to assess the reliability of external carotid-femoral PWV values measured by well-validated external devices in comparison with MRI acquisitions of PWV and aortic mechanical properties in a population of obese subjects. PWV was measured with PulsePen and Complior II devices in 32 volunteers (18 men and 14 women), aged 46 to 65 years (mean: 55.7±5.1 years), presenting with isolated abdominal obesity, with a waist circumference >102 cm for men and >88 cm for women, and a body mass index between 27 and 35. These results were then compared with MRI PWV values and cross-sectional MRI thoracic aorta distensibility values. MRI PWV values were positively correlated with PWV measured by both PulsePen ( r =0.47; P =0.005) and Complior ( r =0.43; P =0.01). Aortic cross-sectional stiffness was positively correlated with PulsePen PWV ( r =0.42; P =0.02). The same trend was also observed with Complior PWV ( r =0.33; P =0.06). This is the first study comparing transcutaneous PWV measurements with MRI aortic elastic properties in obese subjects. Our results indicate that, for body mass index values ≤35 kg m −2 , PWV measured externally with Complior or PulsePen validly reflect values obtained directly in the thoracic aorta through MRI." @default.
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• W2118761991 date "2009-08-01" @default.
• W2118761991 modified "2023-10-16" @default.
• W2118761991 title "Pulse Wave Velocity Assessment by External Noninvasive Devices and Phase-Contrast Magnetic Resonance Imaging in the Obese" @default.
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• W2118761991 doi "https://doi.org/10.1161/hypertensionaha.109.133645" @default.
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