Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118790147> ?p ?o ?g. }
- W2118790147 endingPage "1792" @default.
- W2118790147 startingPage "1787" @default.
- W2118790147 abstract "BK virus (BKV) infection is an established cause of allograft dysfunction in renal transplant recipients. The relationship between BKV infection and chronic kidney disease (CKD) post–orthotopic liver transplantation (OLT) is not well understood. This study aimed to determine the prevalence of BKV infection, its relationship to CKD and renal function loss over time in patients receiving OLT. Prevalence of BK viruria and viremia were studied in 41 post-OLT patients after a mean 6.5 ± 4.7 years posttransplantation. Renal function was assessed using estimated glomerular filtration rate (eGFR) calculated from the yearly serum creatinine levels using the Modification of Diet in Renal Disease (MDRD) formula. Polymerase chain reaction (PCR) was performed for detection of BKV DNA in urine and plasma. BK viruria was present in 24.2% of patients, but none of these OLT recipients had detectable BK viremia. Decoy cells in the urine were found in 9.7% patients, although none of these patients had BK viruria. CKD, defined as eGFR <60 mL/minute/1.73 m2, was found in 83% of OLT recipients. The yearly decline in eGFR was −6.9 ± 17 and −9.2 ± 18 mL/minute/year in BK viruria–positive and BK viruria–negative patients, respectively (P = 0.39). There was no relationship between the presence or absence of BK viruria and either current eGFR, yearly decline in eGFR, number and type of immunosuppressive agents, or etiology of liver failure. In OLT recipients, BK viruria is not associated with BK viremia or native kidney dysfunction. It appears that the most probable pathway for the development of BKV nephropathy requires a second hit, such as kidney inflammation, kidney ischemia, or donor-recipient human leukocyte antigen mismatch. Liver Transpl 14:1787–1792, 2008. © 2008 AASLD." @default.
- W2118790147 created "2016-06-24" @default.
- W2118790147 creator A5039979198 @default.
- W2118790147 creator A5054580308 @default.
- W2118790147 creator A5058313936 @default.
- W2118790147 creator A5067719448 @default.
- W2118790147 creator A5073382962 @default.
- W2118790147 date "2008-11-24" @default.
- W2118790147 modified "2023-10-10" @default.
- W2118790147 title "Decline in native kidney function in liver transplant recipients is not associated with BK virus infection" @default.
- W2118790147 cites W152368894 @default.
- W2118790147 cites W1964003283 @default.
- W2118790147 cites W1978112619 @default.
- W2118790147 cites W1989209244 @default.
- W2118790147 cites W1996130769 @default.
- W2118790147 cites W2000516190 @default.
- W2118790147 cites W2008211463 @default.
- W2118790147 cites W2008849494 @default.
- W2118790147 cites W2014119693 @default.
- W2118790147 cites W2020307907 @default.
- W2118790147 cites W2026399575 @default.
- W2118790147 cites W2035597292 @default.
- W2118790147 cites W2036939431 @default.
- W2118790147 cites W2038801091 @default.
- W2118790147 cites W2047305338 @default.
- W2118790147 cites W2055864845 @default.
- W2118790147 cites W2067222383 @default.
- W2118790147 cites W2067953279 @default.
- W2118790147 cites W2088168913 @default.
- W2118790147 cites W2097389207 @default.
- W2118790147 cites W2105823869 @default.
- W2118790147 cites W2115280883 @default.
- W2118790147 cites W2118181878 @default.
- W2118790147 cites W2134672034 @default.
- W2118790147 cites W2146284689 @default.
- W2118790147 cites W2160426645 @default.
- W2118790147 cites W2168268474 @default.
- W2118790147 cites W4211003049 @default.
- W2118790147 doi "https://doi.org/10.1002/lt.21627" @default.
- W2118790147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19025923" @default.
- W2118790147 hasPublicationYear "2008" @default.
- W2118790147 type Work @default.
- W2118790147 sameAs 2118790147 @default.
- W2118790147 citedByCount "18" @default.
- W2118790147 countsByYear W21187901472012 @default.
- W2118790147 countsByYear W21187901472014 @default.
- W2118790147 countsByYear W21187901472015 @default.
- W2118790147 countsByYear W21187901472016 @default.
- W2118790147 countsByYear W21187901472018 @default.
- W2118790147 countsByYear W21187901472020 @default.
- W2118790147 countsByYear W21187901472021 @default.
- W2118790147 crossrefType "journal-article" @default.
- W2118790147 hasAuthorship W2118790147A5039979198 @default.
- W2118790147 hasAuthorship W2118790147A5054580308 @default.
- W2118790147 hasAuthorship W2118790147A5058313936 @default.
- W2118790147 hasAuthorship W2118790147A5067719448 @default.
- W2118790147 hasAuthorship W2118790147A5073382962 @default.
- W2118790147 hasBestOaLocation W21187901471 @default.
- W2118790147 hasConcept C126322002 @default.
- W2118790147 hasConcept C126894567 @default.
- W2118790147 hasConcept C159641895 @default.
- W2118790147 hasConcept C203014093 @default.
- W2118790147 hasConcept C2522874641 @default.
- W2118790147 hasConcept C2776185481 @default.
- W2118790147 hasConcept C2778199330 @default.
- W2118790147 hasConcept C2778653478 @default.
- W2118790147 hasConcept C2779609443 @default.
- W2118790147 hasConcept C2780303639 @default.
- W2118790147 hasConcept C2780306776 @default.
- W2118790147 hasConcept C2911091166 @default.
- W2118790147 hasConcept C71924100 @default.
- W2118790147 hasConcept C90924648 @default.
- W2118790147 hasConceptScore W2118790147C126322002 @default.
- W2118790147 hasConceptScore W2118790147C126894567 @default.
- W2118790147 hasConceptScore W2118790147C159641895 @default.
- W2118790147 hasConceptScore W2118790147C203014093 @default.
- W2118790147 hasConceptScore W2118790147C2522874641 @default.
- W2118790147 hasConceptScore W2118790147C2776185481 @default.
- W2118790147 hasConceptScore W2118790147C2778199330 @default.
- W2118790147 hasConceptScore W2118790147C2778653478 @default.
- W2118790147 hasConceptScore W2118790147C2779609443 @default.
- W2118790147 hasConceptScore W2118790147C2780303639 @default.
- W2118790147 hasConceptScore W2118790147C2780306776 @default.
- W2118790147 hasConceptScore W2118790147C2911091166 @default.
- W2118790147 hasConceptScore W2118790147C71924100 @default.
- W2118790147 hasConceptScore W2118790147C90924648 @default.
- W2118790147 hasIssue "12" @default.
- W2118790147 hasLocation W21187901471 @default.
- W2118790147 hasLocation W21187901472 @default.
- W2118790147 hasOpenAccess W2118790147 @default.
- W2118790147 hasPrimaryLocation W21187901471 @default.
- W2118790147 hasRelatedWork W1486584413 @default.
- W2118790147 hasRelatedWork W1970866382 @default.
- W2118790147 hasRelatedWork W1984379637 @default.
- W2118790147 hasRelatedWork W2042710484 @default.
- W2118790147 hasRelatedWork W2052365623 @default.
- W2118790147 hasRelatedWork W2064425530 @default.
- W2118790147 hasRelatedWork W2087086071 @default.