Matches in SemOpenAlex for { <https://semopenalex.org/work/W2118865293> ?p ?o ?g. }
- W2118865293 abstract "A comparative treatment planning study was undertaken between proton beam therapy (PBT) and intensity-modulated x-ray therapy (IMXT) for patients with recurrent nasopharyngeal carcinoma (NPC), to assess the potential benefits and limitations of the two treatment modalities.We retrospectively analyzed seven patients with recurrent NPC treated at our proton center with PBT from 2004 to 2007. Eclipse proton treatment planning system and Eclipse inverse treatment planning system for IMXT were employed. For each patient, the IMXT plan was optimized with nine evenly spaced coplanar fields. Three coplanar beams and passive scattering mode were used for PBT. The dose prescription in cobalt Gray equivalent (CGE) for gross tumor volume (GTV) was 66CGE and for planning target volume (PTV), 62.7CGE. Dose-volume histograms (DVH) were used to evaluate the difference in dosimetric distributions for the target volume and the organs at risk (OARs).Optimal target volume coverage and similar target conformation were achieved in both PBT and IMXT. Median conformity index was 0.72 and 0.75 (p=0.15) and median inhomogeneity coefficient was 0.14 and 0.10 (p=0.08) for PBT and IMXT, respectively. Dose to OARs was significantly lower in PBT plans than IMXT. Median maximal dose to the brainstem was 27.89CGE(cobalt Gray equivalent) and 42.45Gy (p< 0.01), and the dose to 5% of the brainstem(D5) was 12.83CGE and 19.47Gy (p< 0.001 ), for PBT and IMXT, respectively. Median maximal dose to the spinal cord was 8.38CGE and 22.91Gy (p< 0.004), and the dose to 5% of the spinal cord was 2.18CGE and 13.62Gy (p< 0.001), for PBT and IMXT, respectively.The use of PBT, when compared with IMXT, resulted in similar levels of tumor conformation. PBT, however, exposed the OARs to a significantly lower dose, effectively sparing the brainstem, spinal cord, optic nerve and chiasm, temporal lobes and parotid glands. The superior dose distributions possible with PBT should translate into reduced morbidity and improved quality of life." @default.
- W2118865293 created "2016-06-24" @default.
- W2118865293 creator A5001305139 @default.
- W2118865293 creator A5008781374 @default.
- W2118865293 creator A5018159613 @default.
- W2118865293 creator A5026020866 @default.
- W2118865293 creator A5057123461 @default.
- W2118865293 creator A5059154435 @default.
- W2118865293 creator A5061979026 @default.
- W2118865293 creator A5062281397 @default.
- W2118865293 creator A5067889161 @default.
- W2118865293 creator A5072925954 @default.
- W2118865293 date "2010-01-01" @default.
- W2118865293 modified "2023-09-26" @default.
- W2118865293 title "A treatment planning comparison between proton beam therapy and intensity-modulated x-ray therapy for recurrent nasopharyngeal carcinoma" @default.
- W2118865293 cites W1965619896 @default.
- W2118865293 cites W1967967795 @default.
- W2118865293 cites W1968218090 @default.
- W2118865293 cites W1977499984 @default.
- W2118865293 cites W1983805637 @default.
- W2118865293 cites W1985829063 @default.
- W2118865293 cites W1991968799 @default.
- W2118865293 cites W1997391888 @default.
- W2118865293 cites W2010145019 @default.
- W2118865293 cites W2011506165 @default.
- W2118865293 cites W2019859736 @default.
- W2118865293 cites W2033028851 @default.
- W2118865293 cites W2040145532 @default.
- W2118865293 cites W2040960631 @default.
- W2118865293 cites W2047408264 @default.
- W2118865293 cites W2059775855 @default.
- W2118865293 cites W2063124234 @default.
- W2118865293 cites W2071155486 @default.
- W2118865293 cites W2079281690 @default.
- W2118865293 cites W2115936968 @default.
- W2118865293 cites W2129121210 @default.
- W2118865293 cites W2136931271 @default.
- W2118865293 cites W2160266968 @default.
- W2118865293 cites W2160657334 @default.
- W2118865293 cites W2170317803 @default.
- W2118865293 cites W2332303338 @default.
- W2118865293 doi "https://doi.org/10.3233/xst-2010-0265" @default.
- W2118865293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21045280" @default.
- W2118865293 hasPublicationYear "2010" @default.
- W2118865293 type Work @default.
- W2118865293 sameAs 2118865293 @default.
- W2118865293 citedByCount "10" @default.
- W2118865293 countsByYear W21188652932015 @default.
- W2118865293 countsByYear W21188652932016 @default.
- W2118865293 countsByYear W21188652932021 @default.
- W2118865293 countsByYear W21188652932022 @default.
- W2118865293 crossrefType "journal-article" @default.
- W2118865293 hasAuthorship W2118865293A5001305139 @default.
- W2118865293 hasAuthorship W2118865293A5008781374 @default.
- W2118865293 hasAuthorship W2118865293A5018159613 @default.
- W2118865293 hasAuthorship W2118865293A5026020866 @default.
- W2118865293 hasAuthorship W2118865293A5057123461 @default.
- W2118865293 hasAuthorship W2118865293A5059154435 @default.
- W2118865293 hasAuthorship W2118865293A5061979026 @default.
- W2118865293 hasAuthorship W2118865293A5062281397 @default.
- W2118865293 hasAuthorship W2118865293A5067889161 @default.
- W2118865293 hasAuthorship W2118865293A5072925954 @default.
- W2118865293 hasConcept C126838900 @default.
- W2118865293 hasConcept C201645570 @default.
- W2118865293 hasConcept C2778997737 @default.
- W2118865293 hasConcept C2779244869 @default.
- W2118865293 hasConcept C2989005 @default.
- W2118865293 hasConcept C509974204 @default.
- W2118865293 hasConcept C71924100 @default.
- W2118865293 hasConceptScore W2118865293C126838900 @default.
- W2118865293 hasConceptScore W2118865293C201645570 @default.
- W2118865293 hasConceptScore W2118865293C2778997737 @default.
- W2118865293 hasConceptScore W2118865293C2779244869 @default.
- W2118865293 hasConceptScore W2118865293C2989005 @default.
- W2118865293 hasConceptScore W2118865293C509974204 @default.
- W2118865293 hasConceptScore W2118865293C71924100 @default.
- W2118865293 hasLocation W21188652931 @default.
- W2118865293 hasLocation W21188652932 @default.
- W2118865293 hasOpenAccess W2118865293 @default.
- W2118865293 hasPrimaryLocation W21188652931 @default.
- W2118865293 hasRelatedWork W1000041689 @default.
- W2118865293 hasRelatedWork W1512800867 @default.
- W2118865293 hasRelatedWork W1772828230 @default.
- W2118865293 hasRelatedWork W1968218090 @default.
- W2118865293 hasRelatedWork W1979045673 @default.
- W2118865293 hasRelatedWork W1985740492 @default.
- W2118865293 hasRelatedWork W1999416550 @default.
- W2118865293 hasRelatedWork W2034015350 @default.
- W2118865293 hasRelatedWork W2127494183 @default.
- W2118865293 hasRelatedWork W2129121210 @default.
- W2118865293 hasRelatedWork W2131065973 @default.
- W2118865293 hasRelatedWork W2145944546 @default.
- W2118865293 hasRelatedWork W2160657334 @default.
- W2118865293 hasRelatedWork W2359472163 @default.
- W2118865293 hasRelatedWork W2368280054 @default.
- W2118865293 hasRelatedWork W2408091808 @default.
- W2118865293 hasRelatedWork W2968210883 @default.
- W2118865293 hasRelatedWork W3031381920 @default.
- W2118865293 hasRelatedWork W30869299 @default.
- W2118865293 hasRelatedWork W3112413869 @default.