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- W2118938224 abstract "Lactobacillus plantarum is part of the natural microbiota of many food fermentations as well as the human gastro-intestinal tract. The cytosolic fraction of the proteome of L. plantarum WCFS1, whose genome has been sequenced, was studied. 2-DE was used to investigate the proteins from the cytosolic fraction isolated from mid- and late-log, early- and late-stationary phase cells to generate reference maps of different growth conditions offering more knowledge of the metabolic behavior of this bacterium. From this fraction, a total of 200 protein spots were identified by MALDI-MS and a proteome production map was constructed to facilitate further studies such as detection of suitable biomarkers for specific growth conditions. More than half (57%) of the identified proteins were predicted to be involved in metabolic pathways of the bacterium. The protein profile changed during the growth of the bacteria such that 29% of the identified proteins involved in anabolic pathways were at least twofold up-regulated throughout the mid- and late-exponential and early-stationary phases. In the late-stationary phase, six proteins involved in stress or with a potential role for survival during starvation were up-regulated significantly." @default.
- W2118938224 created "2016-06-24" @default.
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- W2118938224 date "2006-12-01" @default.
- W2118938224 modified "2023-09-23" @default.
- W2118938224 title "Proteomic analysis of log to stationary growth phaseLactobacillus plantarum cells and a 2-DE database" @default.
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- W2118938224 doi "https://doi.org/10.1002/pmic.200600361" @default.
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