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- W2119048297 abstract "Noroviruses are an important cause of acute gastroenteritis. Increasing data showed that the GII-4 strains are predominant worldwide and new GII-4 variants emerge every 1–2 years causing major epidemics. Surveillance of gastroenteritis in hospitalized children under 5 years of age in China is described. Among 1,110 specimens, 114 (10.3%) were positive for noroviruses, which was higher than adenoviruses (7.6%), astroviruses (3.5%), and sapoviruses (0.9%) and only lower than group A rotaviruses (40.6%). Thirty-eight of the 114 positive norovirus cases were co-infected with other enteric viruses. Five norovirus genotypes (GI-2, GI-4, GII-3, GII-4, and GII-14) were detected, with GII-4/2006b the most predominant type (64.9%). The reported recombinant of GII-3 capsid and GII-4 polymerase described previously was also detected frequently and a recombinant of GII-14 capsid and GII-6 polymerase was found for the first time. This study suggests that continual surveillance focusing on strain variation and dynamic change is important for understanding the epidemiology and development of a strategy for disease control and prevention. J. Med. Virol. 80:1997–2004, 2008. © 2008 Wiley-Liss, Inc." @default.
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- W2119048297 date "2008-11-01" @default.
- W2119048297 modified "2023-10-18" @default.
- W2119048297 title "Emergence of the GII4/2006b variant and recombinant noroviruses in China" @default.
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- W2119048297 doi "https://doi.org/10.1002/jmv.21308" @default.
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