Matches in SemOpenAlex for { <https://semopenalex.org/work/W2119080044> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2119080044 endingPage "3490" @default.
- W2119080044 startingPage "3484" @default.
- W2119080044 abstract "Capnocytophaga canimorsus is a gram-negative rod that causes opportunistic infections resulting in bacteremia, septicemia, meningitis, and death in immunocompromised, splenectomized, and alcoholic individuals. Infections caused by a related species, Capnocytophaga cynodegmi, remain localized at the site of the wound where the organism is introduced. Both organisms are part of the normal canine oral flora and are introduced through puncture wounds via dog bites. We found that both C. canimorsus and C. cynodegmi attach, are phagocytized, and multiply intracellularly in J774 mouse macrophage cells. After 48 h of infection by C. canimorsus, large sections of the macrophage cell layer were observed to detach and lyse, while the monolayer infected with C. cynodegmi demonstrated no cytotoxic effects. Tissue culture supernatants from the C. canimorsus-infected J774 cells filtered through a 0.22-micron-pore membrane produced a similar effect on fresh monolayers, while filtrates from C. cynodegmi and uninfected controls produced no effect. No endotoxin release was observed in these supernatants. We conclude that the cytotoxic phenotype of C. canimorsus is the likely result of a toxin produced by this organism." @default.
- W2119080044 created "2016-06-24" @default.
- W2119080044 creator A5007081465 @default.
- W2119080044 creator A5009089009 @default.
- W2119080044 creator A5014960053 @default.
- W2119080044 creator A5066244237 @default.
- W2119080044 date "1995-09-01" @default.
- W2119080044 modified "2023-10-12" @default.
- W2119080044 title "Intracellular multiplication and toxic destruction of cultured macrophages by Capnocytophaga canimorsus" @default.
- W2119080044 cites W122676255 @default.
- W2119080044 cites W1506087988 @default.
- W2119080044 cites W1543955252 @default.
- W2119080044 cites W1596742772 @default.
- W2119080044 cites W1664304737 @default.
- W2119080044 cites W1966037435 @default.
- W2119080044 cites W1978144395 @default.
- W2119080044 cites W2010571324 @default.
- W2119080044 cites W2012337474 @default.
- W2119080044 cites W2016545287 @default.
- W2119080044 cites W2030397074 @default.
- W2119080044 cites W2031473411 @default.
- W2119080044 cites W2061427784 @default.
- W2119080044 cites W2066408540 @default.
- W2119080044 cites W2095892237 @default.
- W2119080044 cites W2099144632 @default.
- W2119080044 cites W2117524750 @default.
- W2119080044 cites W2155307333 @default.
- W2119080044 cites W2168211151 @default.
- W2119080044 cites W2259956260 @default.
- W2119080044 cites W2345544016 @default.
- W2119080044 cites W2462730741 @default.
- W2119080044 cites W2466619828 @default.
- W2119080044 cites W2467225728 @default.
- W2119080044 doi "https://doi.org/10.1128/iai.63.9.3484-3490.1995" @default.
- W2119080044 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/173481" @default.
- W2119080044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7642281" @default.
- W2119080044 hasPublicationYear "1995" @default.
- W2119080044 type Work @default.
- W2119080044 sameAs 2119080044 @default.
- W2119080044 citedByCount "31" @default.
- W2119080044 countsByYear W21190800442012 @default.
- W2119080044 countsByYear W21190800442013 @default.
- W2119080044 countsByYear W21190800442015 @default.
- W2119080044 countsByYear W21190800442022 @default.
- W2119080044 crossrefType "journal-article" @default.
- W2119080044 hasAuthorship W2119080044A5007081465 @default.
- W2119080044 hasAuthorship W2119080044A5009089009 @default.
- W2119080044 hasAuthorship W2119080044A5014960053 @default.
- W2119080044 hasAuthorship W2119080044A5066244237 @default.
- W2119080044 hasBestOaLocation W21190800441 @default.
- W2119080044 hasConcept C109316439 @default.
- W2119080044 hasConcept C154317977 @default.
- W2119080044 hasConcept C202751555 @default.
- W2119080044 hasConcept C2777367657 @default.
- W2119080044 hasConcept C2778576240 @default.
- W2119080044 hasConcept C2779244956 @default.
- W2119080044 hasConcept C2779443120 @default.
- W2119080044 hasConcept C501593827 @default.
- W2119080044 hasConcept C523546767 @default.
- W2119080044 hasConcept C54355233 @default.
- W2119080044 hasConcept C55493867 @default.
- W2119080044 hasConcept C86803240 @default.
- W2119080044 hasConcept C89423630 @default.
- W2119080044 hasConceptScore W2119080044C109316439 @default.
- W2119080044 hasConceptScore W2119080044C154317977 @default.
- W2119080044 hasConceptScore W2119080044C202751555 @default.
- W2119080044 hasConceptScore W2119080044C2777367657 @default.
- W2119080044 hasConceptScore W2119080044C2778576240 @default.
- W2119080044 hasConceptScore W2119080044C2779244956 @default.
- W2119080044 hasConceptScore W2119080044C2779443120 @default.
- W2119080044 hasConceptScore W2119080044C501593827 @default.
- W2119080044 hasConceptScore W2119080044C523546767 @default.
- W2119080044 hasConceptScore W2119080044C54355233 @default.
- W2119080044 hasConceptScore W2119080044C55493867 @default.
- W2119080044 hasConceptScore W2119080044C86803240 @default.
- W2119080044 hasConceptScore W2119080044C89423630 @default.
- W2119080044 hasIssue "9" @default.
- W2119080044 hasLocation W21190800441 @default.
- W2119080044 hasLocation W21190800442 @default.
- W2119080044 hasLocation W21190800443 @default.
- W2119080044 hasOpenAccess W2119080044 @default.
- W2119080044 hasPrimaryLocation W21190800441 @default.
- W2119080044 hasRelatedWork W1963891627 @default.
- W2119080044 hasRelatedWork W2045299745 @default.
- W2119080044 hasRelatedWork W2051018641 @default.
- W2119080044 hasRelatedWork W2366562690 @default.
- W2119080044 hasRelatedWork W2395219877 @default.
- W2119080044 hasRelatedWork W2411369229 @default.
- W2119080044 hasRelatedWork W2796949944 @default.
- W2119080044 hasRelatedWork W3167838867 @default.
- W2119080044 hasRelatedWork W4301072685 @default.
- W2119080044 hasRelatedWork W1986075224 @default.
- W2119080044 hasVolume "63" @default.
- W2119080044 isParatext "false" @default.
- W2119080044 isRetracted "false" @default.
- W2119080044 magId "2119080044" @default.
- W2119080044 workType "article" @default.