FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2119152348> ?p ?o ?g. }

• W2119152348 endingPage "680" @default.
• W2119152348 startingPage "671" @default.
• W2119152348 abstract "Thymus-derived (T) cells obtained from three categories of in vitro antigen-induced proliferative responses were assayed as sources of helper T cells. These categories are exemplified by (a) direct stimulation of keyhole limpet hemocyanin (KLH)-primed cell with KLH, which results in high indexes of proliferation; (b) direct stimulation of apoferritin-primed cells with apoferritin, which does not result in indexes of proliferation above background levels; (c) trans-stimulation of unprimed cells with X-irradiated KLH-primed cells which results in indexes of proliferation comparable to category (a). Our results indicate that levels of [3H]thymidine incorporation by proliferating populations are not an accurate reflection of helper T cell generation. Directly stimulated KLH and apoferritin-primed cells give rise to highly enriched populations of antigen-specific helper T cells which support both IgM and IgG antibody responses in vitro. Moreover, these specific helper T cells are functionally restricted by products encoded by the I region of the major histocompatibility complex (MHC). Helper T cells generated in KLH-trans-stimulated cultures are not KLH-specific in that comparable levels of helper activity are expressed using either KLH or apoferritin as carriers. These non-KLH-specific helper T cells only support the production of IgM antibody in vitro and they are not functionally restricted by MHC products." @default.
• W2119152348 created "2016-06-24" @default.
• W2119152348 creator A5043645134 @default.
• W2119152348 creator A5087421876 @default.
• W2119152348 date "1979-09-01" @default.
• W2119152348 modified "2023-09-23" @default.
• W2119152348 title "Helper activity of T cells stimulated in long-term culture" @default.
• W2119152348 cites W1554123276 @default.
• W2119152348 cites W159354068 @default.
• W2119152348 cites W1601479557 @default.
• W2119152348 cites W1964532737 @default.
• W2119152348 cites W1968367408 @default.
• W2119152348 cites W1969138884 @default.
• W2119152348 cites W1971235188 @default.
• W2119152348 cites W1975649472 @default.
• W2119152348 cites W1988244726 @default.
• W2119152348 cites W1988953076 @default.
• W2119152348 cites W2010164441 @default.
• W2119152348 cites W2022743246 @default.
• W2119152348 cites W2027540416 @default.
• W2119152348 cites W2027771189 @default.
• W2119152348 cites W2029986007 @default.
• W2119152348 cites W2031948257 @default.
• W2119152348 cites W2054633517 @default.
• W2119152348 cites W2057863810 @default.
• W2119152348 cites W2060800940 @default.
• W2119152348 cites W2066562659 @default.
• W2119152348 cites W2067919447 @default.
• W2119152348 cites W2080909530 @default.
• W2119152348 cites W2084093106 @default.
• W2119152348 cites W2103320120 @default.
• W2119152348 cites W2120370266 @default.
• W2119152348 cites W2124140989 @default.
• W2119152348 cites W2134192381 @default.
• W2119152348 cites W2141155302 @default.
• W2119152348 cites W2152214043 @default.
• W2119152348 cites W2157626085 @default.
• W2119152348 cites W2164712805 @default.
• W2119152348 cites W2287324627 @default.
• W2119152348 cites W4313309117 @default.
• W2119152348 cites W4313309946 @default.
• W2119152348 cites W4313310673 @default.
• W2119152348 cites W4313310687 @default.
• W2119152348 cites W4313310712 @default.
• W2119152348 cites W4313315209 @default.
• W2119152348 cites W4313316558 @default.
• W2119152348 cites W4313338247 @default.
• W2119152348 doi "https://doi.org/10.1002/eji.1830090904" @default.
• W2119152348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/92411" @default.
• W2119152348 hasPublicationYear "1979" @default.
• W2119152348 type Work @default.
• W2119152348 sameAs 2119152348 @default.
• W2119152348 citedByCount "39" @default.
• W2119152348 crossrefType "journal-article" @default.
• W2119152348 hasAuthorship W2119152348A5043645134 @default.
• W2119152348 hasAuthorship W2119152348A5087421876 @default.
• W2119152348 hasConcept C129374314 @default.
• W2119152348 hasConcept C147483822 @default.
• W2119152348 hasConcept C153911025 @default.
• W2119152348 hasConcept C154317977 @default.
• W2119152348 hasConcept C202751555 @default.
• W2119152348 hasConcept C203014093 @default.
• W2119152348 hasConcept C207936829 @default.
• W2119152348 hasConcept C2776090121 @default.
• W2119152348 hasConcept C2776727803 @default.
• W2119152348 hasConcept C2781136212 @default.
• W2119152348 hasConcept C39347974 @default.
• W2119152348 hasConcept C54355233 @default.
• W2119152348 hasConcept C67662055 @default.
• W2119152348 hasConcept C86803240 @default.
• W2119152348 hasConcept C8891405 @default.
• W2119152348 hasConcept C95444343 @default.
• W2119152348 hasConceptScore W2119152348C129374314 @default.
• W2119152348 hasConceptScore W2119152348C147483822 @default.
• W2119152348 hasConceptScore W2119152348C153911025 @default.
• W2119152348 hasConceptScore W2119152348C154317977 @default.
• W2119152348 hasConceptScore W2119152348C202751555 @default.
• W2119152348 hasConceptScore W2119152348C203014093 @default.
• W2119152348 hasConceptScore W2119152348C207936829 @default.
• W2119152348 hasConceptScore W2119152348C2776090121 @default.
• W2119152348 hasConceptScore W2119152348C2776727803 @default.
• W2119152348 hasConceptScore W2119152348C2781136212 @default.
• W2119152348 hasConceptScore W2119152348C39347974 @default.
• W2119152348 hasConceptScore W2119152348C54355233 @default.
• W2119152348 hasConceptScore W2119152348C67662055 @default.
• W2119152348 hasConceptScore W2119152348C86803240 @default.
• W2119152348 hasConceptScore W2119152348C8891405 @default.
• W2119152348 hasConceptScore W2119152348C95444343 @default.
• W2119152348 hasIssue "9" @default.
• W2119152348 hasLocation W21191523481 @default.
• W2119152348 hasLocation W21191523482 @default.
• W2119152348 hasOpenAccess W2119152348 @default.
• W2119152348 hasPrimaryLocation W21191523481 @default.
• W2119152348 hasRelatedWork W1810861369 @default.
• W2119152348 hasRelatedWork W2002809032 @default.
• W2119152348 hasRelatedWork W2082657282 @default.
• W2119152348 hasRelatedWork W2086033359 @default.
• W2119152348 hasRelatedWork W2139860153 @default.

• next