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• W2119259626 abstract "Lack of human exposure data is frequently reported as a critical gap in risk assessments of environmental pollutants, especially regarding “new” pollutants. The objectives of this study were to assess serum levels of the persistent 2,2‘,4,4‘,5,5‘-hexachlorobiphenyl (CB-153), hydroxylated polychlorinated biphenyl metabolites (OH-PCBs), polybrominated diphenyl ethers (PBDEs), and hexabromocyclododecanes (HBCDDs) in a group of Swedish middle-aged and elderly women expected to be relatively highly exposed, and to evaluate the impact of potential determinants (e.g., fish intake, age) for the inter-individual variation, as well as to investigate the association between these pollutants and bone density. No associations were found between bone mineral density or biochemical markers of bone metabolism and the analyzed environmental pollutants. Relatively high levels of CB-153 (median 260 ng/g fat) and Σ3OH-PCBs (median 1.7 ng/mL serum), and low concentrations of Σ6PBDEs (median 3.6 ng/g fat) were determined. Total level of HBCDDs in serum was quantified by gas chromatography with mass spectrometric detection (median 0.5 ng/g fat). HBCDD diastereomeric and enantiomeric patterns were determined by liquid chromatography with mass spectrometric detection. The dominating stereoisomer was (−)α-HBCDD, but 1−3% of γ-HBCDD was also detected in the serum samples." @default.
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• W2119259626 date "2006-09-09" @default.
• W2119259626 modified "2023-10-16" @default.
• W2119259626 title "Hydroxy-PCBs, PBDEs, and HBCDDs in Serum from an Elderly Population of Swedish Fishermen's Wives and Associations with Bone Density" @default.
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• W2119259626 doi "https://doi.org/10.1021/es0610941" @default.
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