FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2119318194> ?p ?o ?g. }

• W2119318194 abstract "Despite Helicobacter pylori eradication, gastric inflammation persists for months or years. Preliminary results have indicated that an increase in gastric permeability could be one reason. Our aim was to evaluate the effect of a mucosal protective drug, rebamipide, on gastric permeability in a model of H. felis-infected mice.Thirty-three C57/BL6 mice were inoculated with H. felis, and seven controls were kept non-inoculated. After 2 months 20 infected mice were treated with omeprazole, amoxicillin, and clarithromycin for 1 week and then for 4 weeks with either rebamipide (n = 9) or placebo (n = 11). The 13 remaining mice were kept untreated. After cessation of treatment, a fragment of antrum obtained from each mouse was mounted in a small Ussing chamber to study the electric resistance of the tissue (R) and antral permeability.No modification of the paracellular permeability (R, JNa, JMan) was observed in either group. However, the transcellular permeability to horseradish peroxidase (HRP) was significantly increased in H. felis-infected non-treated mice (1131 +/- 463, 948 +/- 339, and 182 +/- 312 ng/h x cm2) as compared with non-infected controls (469 +/- 262, 458 +/- 261, and 10 +/- 6 ng/ h x cm2, for J3H-HRP, JD, and JHRPi, respectively) (P < 0.003). Eradication of the bacteria by antibiotics without subsequent treatment with rebamipide led to a non-significant decrease in the HRP fluxes. However, when rebamipide was used after the antibiotic treatment, a significant (P < 0.01) decrease in HRP fluxes as compared with non-treated mice was observed.These results confirm that gastric permeability to macromolecules remains increased despite H. felis eradication and show that rebamipide can facilitate the normalization of gastric permeability to macromolecules after bacterial eradication." @default.
• W2119318194 created "2016-06-24" @default.
• W2119318194 creator A5050209583 @default.
• W2119318194 creator A5055607557 @default.
• W2119318194 creator A5065206007 @default.
• W2119318194 creator A5071800605 @default.
• W2119318194 creator A5072576853 @default.
• W2119318194 creator A5083476802 @default.
• W2119318194 date "2000-01-01" @default.
• W2119318194 modified "2023-10-18" @default.
• W2119318194 title "Positive Effect of Rebamipide on Gastric Permeability in Mice after Eradication of Helicobacter felis" @default.
• W2119318194 cites W1542736379 @default.
• W2119318194 cites W1996625135 @default.
• W2119318194 cites W2004088421 @default.
• W2119318194 cites W2007051027 @default.
• W2119318194 cites W2012038965 @default.
• W2119318194 cites W2019925655 @default.
• W2119318194 cites W2025454607 @default.
• W2119318194 cites W2038213196 @default.
• W2119318194 cites W2042607741 @default.
• W2119318194 cites W2087893483 @default.
• W2119318194 cites W2094989423 @default.
• W2119318194 cites W2165350984 @default.
• W2119318194 cites W23949651 @default.
• W2119318194 cites W98217889 @default.
• W2119318194 doi "https://doi.org/10.1080/003655200750023714" @default.
• W2119318194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10868448" @default.
• W2119318194 hasPublicationYear "2000" @default.
• W2119318194 type Work @default.
• W2119318194 sameAs 2119318194 @default.
• W2119318194 citedByCount "15" @default.
• W2119318194 countsByYear W21193181942012 @default.
• W2119318194 countsByYear W21193181942013 @default.
• W2119318194 countsByYear W21193181942018 @default.
• W2119318194 crossrefType "journal-article" @default.
• W2119318194 hasAuthorship W2119318194A5050209583 @default.
• W2119318194 hasAuthorship W2119318194A5055607557 @default.
• W2119318194 hasAuthorship W2119318194A5065206007 @default.
• W2119318194 hasAuthorship W2119318194A5071800605 @default.
• W2119318194 hasAuthorship W2119318194A5072576853 @default.
• W2119318194 hasAuthorship W2119318194A5083476802 @default.
• W2119318194 hasConcept C120882062 @default.
• W2119318194 hasConcept C126322002 @default.
• W2119318194 hasConcept C185592680 @default.
• W2119318194 hasConcept C203014093 @default.
• W2119318194 hasConcept C2776409635 @default.
• W2119318194 hasConcept C2776962512 @default.
• W2119318194 hasConcept C2777367493 @default.
• W2119318194 hasConcept C2777498785 @default.
• W2119318194 hasConcept C2779422922 @default.
• W2119318194 hasConcept C2779708577 @default.
• W2119318194 hasConcept C2779790080 @default.
• W2119318194 hasConcept C2780832600 @default.
• W2119318194 hasConcept C41625074 @default.
• W2119318194 hasConcept C501593827 @default.
• W2119318194 hasConcept C55493867 @default.
• W2119318194 hasConcept C60903277 @default.
• W2119318194 hasConcept C71924100 @default.
• W2119318194 hasConcept C86803240 @default.
• W2119318194 hasConcept C89423630 @default.
• W2119318194 hasConcept C90924648 @default.
• W2119318194 hasConcept C98274493 @default.
• W2119318194 hasConceptScore W2119318194C120882062 @default.
• W2119318194 hasConceptScore W2119318194C126322002 @default.
• W2119318194 hasConceptScore W2119318194C185592680 @default.
• W2119318194 hasConceptScore W2119318194C203014093 @default.
• W2119318194 hasConceptScore W2119318194C2776409635 @default.
• W2119318194 hasConceptScore W2119318194C2776962512 @default.
• W2119318194 hasConceptScore W2119318194C2777367493 @default.
• W2119318194 hasConceptScore W2119318194C2777498785 @default.
• W2119318194 hasConceptScore W2119318194C2779422922 @default.
• W2119318194 hasConceptScore W2119318194C2779708577 @default.
• W2119318194 hasConceptScore W2119318194C2779790080 @default.
• W2119318194 hasConceptScore W2119318194C2780832600 @default.
• W2119318194 hasConceptScore W2119318194C41625074 @default.
• W2119318194 hasConceptScore W2119318194C501593827 @default.
• W2119318194 hasConceptScore W2119318194C55493867 @default.
• W2119318194 hasConceptScore W2119318194C60903277 @default.
• W2119318194 hasConceptScore W2119318194C71924100 @default.
• W2119318194 hasConceptScore W2119318194C86803240 @default.
• W2119318194 hasConceptScore W2119318194C89423630 @default.
• W2119318194 hasConceptScore W2119318194C90924648 @default.
• W2119318194 hasConceptScore W2119318194C98274493 @default.
• W2119318194 hasLocation W21193181941 @default.
• W2119318194 hasLocation W21193181942 @default.
• W2119318194 hasOpenAccess W2119318194 @default.
• W2119318194 hasPrimaryLocation W21193181941 @default.
• W2119318194 hasRelatedWork W1528908055 @default.
• W2119318194 hasRelatedWork W1582240196 @default.
• W2119318194 hasRelatedWork W17083376 @default.
• W2119318194 hasRelatedWork W1963523625 @default.
• W2119318194 hasRelatedWork W2004088421 @default.
• W2119318194 hasRelatedWork W2010241782 @default.
• W2119318194 hasRelatedWork W2013569894 @default.
• W2119318194 hasRelatedWork W2081419858 @default.
• W2119318194 hasRelatedWork W2114202872 @default.
• W2119318194 hasRelatedWork W2164764264 @default.
• W2119318194 hasRelatedWork W2352066551 @default.
• W2119318194 hasRelatedWork W2354999377 @default.
• W2119318194 hasRelatedWork W2370207596 @default.

• next